Chapter 4: Basic Research with DNA Microarrays
Section 4.1 Introduction
- What happened to my home brew?
- What can we learn from stressed out yeast?
- Why are there so many copies of some genes
but not others?
- How well do promoters control gene expression?
- Are promoters able to work in reverse?
4.1 How do you transform the data to
4.2 How do you measure similarity
between expression patterns?
4.3 How do you cluster genes?
Section 4.2 Alternative
Uses of DNA Microarrays
- Why do so many different genes share the
same expression profile?
- Can cells verify their own genes?
4.4 Is it useful to compare the columns
of a gene expression matrix?
Chapter 5: Applied Research with DNA Microarrays
Section 5.1 Cancer and Genomic
- Are there better ways to diagnose cancer?
- Can breast cancer be categorized with microarrays,
- What genomic changes occur in cancer cells?
5.1 What are signature genes, and how
do you use them?
Section 5.2 Improving Healthcare
with DNA Microarrays
- Why is the tuberculosis vaccine is less effective
- How does this drug work?
- Can we predict which drugs will work best
in different cancers?
- What happens when you accumulate fat?
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