We can get a better look at the helices and beta sheets. Click
here to see the beta sheets. The YELLOW
sheets are anti-parallel while the
MAGENTA sheets are parallel. To see the helices,
shown in VIOLET, click
here. Within the C domain is a double beta-alpha-beta motif. This is a motif shared with TyrOH,
TrpOH, and phosphoglycerate dehydrogenase, involved in serine biosynthesis
(see previous assignments for more about similar proteins) (Kobe et al. 1999).
Now lets look just at the N regulatory terminus by clicking here. The BLUE N terminus (19-33) region is regulatory region for the C domain active sites. To see the regulatory sequence interact with the C domain active site, click here (Kobe et al. 1999).
Kobe B, et al. 1999 May. Structural basis of autoregulation of phenylalanine hydroxylase. Nature Structural Biology 6; 5: 442-8. Abstract available at <http://www.nature.com/cgi-taf/DynaPage.taf?file=/nsmb/journal/v6/n5/abs/nsb0599_442.html&dynoptions=doi1108519696>. Accessed 2005 Feb 9.
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