Gene Networks Database


Strongylocentrotus purpuratus Genes in Development: Spliceosomal small nuclear RNAs


SpU6


Function

SpU6 gene encodes the spliceosomal small nuclear RNAs and ispresent in tandemly repeated units. Each tandemly repeated unitcontains a single functional U6 gene, whose sequence is the sameas that of the major U6 snRNAs expressed in S.purpuratus eggs andembryos (Li J.-M. et al., 1994).

Protein

Subcellular location

Nuclear

Expression Pattern

The SpU6 gene is expressed in oogenesis and early embryogenesis (Li J.-M. et al., 1994).The snRNA synthesis is activated at about the 32-cell stageand the synthesis continues at a high rate until after hatching.The rate of accumulation declines dramatically between blastula and gastrula and remains at a relatively low rate through the pluteus stage (Stefanovic B. et al., 1991).

mRNA level

Temporal accumulation

Reference 1: Li J.-M. et al., 1994
Reference 1: Stefanovic B. et al., 1991

Stage
Egg
32-cell stage
Hatching blastula
Gastrula
Pluteus
Level
+ -
+
+
+ -
+ -


Sequences


Regulatory Regions


Regulatory Connections

Upstream Genes

SpF1

SpU6

Downstream Genes


Evolutionary homologues


Links


Bibliography


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