A. Malcolm Campbell


Spotted Scanning Standards (S3)

Emily Oldham and Dan Pierce ('03)



Experimental Design


Need Stronger Signal

3DNA Dendrimer Advantage = 300+ dyes per binding


 

 

 


 

DNA Concentrations Printed

 


 

Establish Scanning Parameters

 


 

Concentrations Alters Ratios

 


Sequence-Specific Variations

 


Altered 3DNA Sticky Ends

 


Clean Up Printed DNA: Clone PCR Products

 

 


Plasmids Improve Signal

 


 

Microarrays Underestimate Fold Change

 

 


Biology Department


© Copyright 2004 Department of Biology, Davidson College, Davidson, NC 28036
Send comments, questions, and suggestions to: macampbell@davidson.edu