*This web page was produced as an assignment for an undergraduate course at Davidson College.*DNA Polymerase
During DNA replication, DNA polymerase catalyzes the elongation of the new DNA. As replication begins at the origins of replication, new bases align with their complementary bases on the template strand. Using nucleotide triphosphates as a substrate, DNA polymerase polymerizes, or adds, the new bases to the growing 3' end of the new DNA strand.
Figure 1: DNA polymerase adds nucleotides to the new DNA strand.
Click here to view DNA Polymerase III (D subunit) from E. coli
DNA Polymerase is a fundamental component to the replication of DNA, thus it is found in all varieties of species. Using Genbank, the cDNA and translated amino acid sequences for five species are listed below.
Homo
sapiens
Mus
musculus
Schizosaccharomyces
pombe
Drosophila
melanogaster
Mesocricetus
auratus
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