NM_012734 . Rattus norvegicus ...[gi:6981021]
PubMed, Protein, LinkOut
LOCUS NM_012734 3653
bp mRNA
ROD 12-FEB-2000
DEFINITION Rattus norvegicus Hexokinase 1 (Hk1), mRNA.
ACCESSION NM_012734
VERSION NM_012734.1 GI:6981021
KEYWORDS .
SOURCE Norway rat.
ORGANISM Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia;
Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Rattus.
REFERENCE 1 (sites)
AUTHORS Schwab,D.A. and Wilson,J.E.
TITLE The complete amino acid sequence of the catalytic
domain of rat
brain hexokinase, deduced from the cloned cDNA
JOURNAL J. Biol. Chem. 263 (7), 3220-3224 (1988)
MEDLINE 88139392
REFERENCE 2 (bases 1 to 3653)
AUTHORS Schwab,D.A. and Wilson,J.E.
TITLE Complete amino acid sequence of rat brain
hexokinase, deduced from
the cloned cDNA, and proposed structure of a mammalian hexokinase
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86 (8), 2563-2567 (1989)
MEDLINE 89202369
COMMENT REFSEQ: This reference sequence was derived
from J04526.1.
PROVISIONAL RefSeq: This is a provisional reference sequence record
that has not yet been subject to human review. The final curated
reference sequence record may be somewhat different from this one.
FEATURES
Location/Qualifiers
source 1..3653
/organism="Rattus norvegicus"
/db_xref="taxon:10116"
/chromosome="20"
/map="20q11"
/tissue_type="brain"
/dev_stage="adult"
gene
1..3653
/gene="Hk1"
/note="RATHEXOKIN"
/db_xref="LocusID:25058"
/db_xref="RATMAP:36618"
CDS
92..2848
/gene="Hk1"
/EC_number="2.7.1.1"
/codon_start=1
/product="hexokinase 1"
/protein_id="NP_036866.1"
/db_xref="GI:6981022"
TRANSLATION: "MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDEILIDILTRFK
KEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKN
QNVSMESEIYDTPENIVHGSGTQLFDHVADCLGDFMEKKKIKDKKLPVGFTFSFPCRQ
SKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCG
YDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTE
FDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKEGLLFEGRITPELLTRGKF
NTSDVSAIEKDKEGIQNAKEILTRLGVEPSDVDCVSVQHICTIVSFRSANLVAATLGA
ILNRLRDNKGTPRLRTTVGVDGSLYKMHPQYSRRFHKTLRRLVPDSDVRFLLSESGTG
KGAAMVTAVAYRLAEQHRQIEETLAHFRLSKQTLMEVKKRLRTEMEMGLRKETNSKAT
VKMLPSFVRSIPDGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYSIPLEI
MQGTGDELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCHQTNLDCGILISWTKGFK
ATDCEGHDVASLLRDAVKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEIGLIVGTGT
NACYMEEMKNVEMVEGNQGQMCINMEWGAFGDNGCLDDIRTDFDKVVDEYSLNSGKQR
FEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQIESDRLALL
QVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAAVVEKIRENRGLDHLNV
TVGVDGTLYKLHPHFSRIMHQTVKELSPKCTVSFLLSEDGSGKGAALITAVGVRLRGD
PSIA"
polyA_signal 3634..3639
polyA_site 3653
BASE COUNT 864 a 982 c
1043 g 764 t
ORIGIN
1 cgccgatctg ccgctggagg accactgctc accagggcta ctgaggagcc actggcccca
61 cacctgcttt tccgcatccc ccaccgtcag catgatcgcc gcgcaactac tggcctatta
121 cttcaccgag ctgaaggatg accaagtcaa aaagattgac aagtatctgt acgccatgcg
181 gctctctgat gagattctga tagatatcct gacacgattc aagaaagaga tgaagaatgg
241 cctctcccgg gattataatc caacagcctc cgtcaagatg ctgcccacct tcgtccggtc
301 cattccggac ggctcagaaa agggggattt cattgccctg gatctcggcg ggtcttcctt
361 tcgaatcctg cgggtgcagg tgaaccacga gaagaaccag aacgtcagca tggagtctga
421 gatctacgac accccagaga acatcgtgca tggcagtgga acccagcttt tcgatcatgt
481 cgctgactgc ctgggagact tcatggagaa aaagaagatc aaggacaaga agttacccgt
541 gggattcaca ttttccttcc cctgccgaca atccaagata gatgaggctg tactgatcac
601 gtggacaaag cggttcaaag ccagtggcgt ggaaggagcg gatgtggtca agttgctgaa
661 taaagccatt aagaagcgag gggactatga tgctaacatt gtcgccgtgg tgaatgacac
721 agtagggacc atgatgacct gcggttatga tgaccaacag tgtgaagtcg gcctgatcat
781 tggcacaggc accaatgctt gctacatgga ggaactgcga cacatcgacc tggtggaagg
841 cgacgagggg aggatgtgta ttaacacgga atggggagcc tttggggatg atgggtccct
901 ggaagacatc cgaaccgagt ttgacagaga gttagaccgt ggatctctca accctgggaa
961 gcagctgttc gagaagatgg tgagcggcat gtacatgggg gagctggtcc ggctaatcct
1021 ggtgaagatg gccaaggaag gcctcttatt cgaagggcgc atcactccag agctgctcac
1081 gaggggaaag ttcaacacta gtgacgtgtc cgccattgaa aaggataagg aaggcattca
1141 aaatgccaag gaaatcttaa cccgcttggg agtggagccg tctgatgttg actgtgtgtc
1201 ggtccagcac atctgcacga tcgtctcctt ccgatcagcc aacctggtgg ccgccacgct
1261 cggtgccatc ttgaaccgcc tgcgggacaa caagggcaca ccacgcctgc ggaccacggt
1321 tggcgtggac ggttctctct acaagatgca cccacagtac tcccggcggt tccacaagac
1381 cctgaggcgc ctggtgcctg actccgacgt ccgtttcctc ctctcagaga gtggcacggg
1441 caagggggcc gccatggtga cggcagtagc ctaccgcctg gctgagcagc accggcagat
1501 tgaggaaacc ctggcccact tccgcctcag caagcagacg ctgatggagg tgaagaagag
1561 gctacggaca gagatggaaa tggggctgag gaaggagacc aacagcaaag ctactgtcaa
1621 aatgctgcct tcttttgtcc ggagcatccc ggatgggact gaacacggtg acttcctggc
1681 cttggatctt ggaggaacga atttccgggt tctgctggta aagatccgca gtgggaaaaa
1741 gagaacagtg gaaatgcaca acaagatcta ctccattccc ctggaaatca tgcagggcac
1801 cggggatgag ctgtttgacc acatcgtctc ctgcatctct gacttcctgg actacatggg
1861 gatcaaaggc ccccggatgc ctctgggctt caccttctca tttccctgcc atcagacgaa
1921 cctggactgt ggaatcttga tctcatggac aaagggtttc aaagccactg actgtgaggg
1981 ccatgatgta gcctccttac tgagggatgc ggtgaagagg agagaggaat ttgacttgga
2041 tgtggtggct gtggtcaacg acaccgtggg caccatgatg acctgtgcgt atgaagaacc
2101 cacttgcgaa attggactca tcgtggggac gggcaccaat gcctgctaca tggaggagat
2161 gaagaatgtg gagatggtgg aggggaacca gggccagatg tgcatcaaca tggagtgggg
2221 cgccttcggt gacaatgggt gtctggatga catcagaaca gactttgaca aagtggtgga
2281 cgaatattct ctaaactctg ggaaacaaag gtttgagaaa atgatcagtg ggatgtacct
2341 gggtgagatc gtccgtaaca tcctgattga cttcaccaag aaaggcttcc tcttccgggg
2401 acagatctcc gaaccactca agacccgagg catctttgag accaagtttc tctctcagat
2461 tgagagtgac cggttagcgc tgctccaggt gcgggccatc cttcagcagc tgggtttgaa
2521 cagcacgtgt gacgacagta tcctggtcaa gaccgtgtgt ggggtggtgt ccaagagggc
2581 ggctcagctg tgtggtgccg gcatggccgc cgtggtggaa aagatcagag agaacagagg
2641 cctagaccat ctgaatgtaa ctgtgggagt ggatgggacg ctctacaaac ttcatccaca
2701 cttctccaga atcatgcacc aaactgtgaa ggaactgtca ccaaagtgta ccgtgtcctt
2761 cctcctgtct gaagacggca gcggcaaggg ggccgccctt atcacagctg tgggcgtgcg
2821 gctcagagga gacccttcga tcgcctaaaa gccaggatcc tcccagcccc cagcccgcca
2881 cccttccagc actcctctct agaaccgacg accacacccc cgtgttccac ccagcaagcc
2941 ctgggagacc cagccagcgc ccactccgcc gcagcagagg gaggaagggg accgcagtaa
3001 cggagcacca cgtagaatac cacccagagc gcgtgtgctg ttgatctgat ctctcgcctg
3061 gacccctaat ccctgccctg ccactctgca tgattcaagt tcgacctggc catgcattgc
3121 ccatgagtga acgtagcggc accccggtgc gtctactgca gatgtccagc taggaaagag
3181 tcccctctct tggacagtct tctgggccct tccaagccca tccgtggagt cggcctctcc
3241 tcccctctcc cccgtgtgaa gtgtgttatc accagcagac actgccggac tcctgcccac
3301 aggggcgtgg cctgaaggcg gagtgtggac atggcactgc tgttccgttc ccttcccctc
3361 ccagcacccg ccgcagcctg ccatcccgtc tggatgtatc gatgccacag aattgtgaat
3421 tgtgtgtccg tccgtggagc cagtcctagc cacattattg acagtcttgc attttgtttt
3481 gtctcctggt ggtgggggtg gaggtggtag gggtgcgcta aggtgggcag tcctgtggga
3541 gaacatcttg ctagaaggaa ccaacccacg aaacaacacc atcactggaa tttccatcgc
3601 ccgaattctt tagtgagcca ttgttgtacg tctagtaaac tttgtactga ttc
The source for these sequences is GenBank
Return to Protein Page
Return to My Molecular Biology Home Page
This page was produced as an assignment for an undergraduate course
at Davidson College.