LOCUS CFU25183
2773 bp mRNA
MAM 15-AUG-1996
DEFINITION Canis familiaris muscle type phosphofructokinase (M-PFK)
mRNA,
complete cds.
ACCESSION U25183
NID g818846
KEYWORDS .
SOURCE dog.
ORGANISM Canis familiaris
Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
Vertebrata; Eutheria; Carnivora; Fissipedia; Canidae; Canis.
REFERENCE 1 (bases 1 to 2773)
AUTHORS Smith,B.F., Stedman,H., Rajpurohit,Y., Henthorn,P.S.,
Wolfe,J.H.,
Patterson,D.F. and Giger,U.
TITLE Molecular basis of canine muscle
type phosphofructokinase
deficiency
JOURNAL J. Biol. Chem. 271 (33), 20070-20074 (1996)
MEDLINE 96355316
REFERENCE 2 (bases 1 to 2773)
AUTHORS Smith,B.F., Henthorn,P., Rajpurohit,Y.,
Stedman,H., Wolfe,J.H.,
Patterson,D.F. and Giger,U.
TITLE Direct Submission
JOURNAL Submitted (18-APR-1995) Bruce F. Smith,
Scott-Ritchey Research
Center, Auburn University, College of Veterinary Medicine, Auburn,
AL 36849, USA
FEATURES
Location/Qualifiers
source
1..2773
/organism="Canis familiaris"
/db_xref="taxon:9615"
/tissue_type="skeletal muscle"
gene
23..2371
/gene="M-PFK"
CDS
23..2371
/gene="M-PFK"
/EC_number="2.7.1.11"
/codon_start=1
/product="muscle type phosphofructokinase"
/db_xref="PID:g818847"
/translation="MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFT
GARVFFVHEGYQGLVDGGDHIREATWESVSMMLQLGGTVIGSARCKDFREREGRLRAA
HNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITAEEATKSSYLNIVG
LVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITTTAQSHQRTFVLEVMGRHCGYLALV
TSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITS
EEIKELVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPAC
VVSLSGNQAVRLPLMECVQVTKDVTKAMNDRKFDEAMKLRGRSFMNNWEVYKLLAHIR
PPVSKTSATMHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQI
EEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANITKFNIQGLIIIGGFEAYTGGL
ELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTICTTCDRIKQSAAGTK
RRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANVEHLVQKMKTTVKR
GLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFDRNFATKMG
AKAMNWMSGKIKESYRNGRIFANTPDSGCVLGMRKRALVFQPVTELKDQTDFDHRIPK
EQWWLKLRPILKILAKYEIDLDTTEHAHLEHISRKRSGETSI"
BASE COUNT 648 a 675
c 815 g 635 t
ORIGIN
1 gctaagacta aaagagtgga
tcatgaccca tgaagagcac catgcagcca aaaccctggg
61 gatcggcaaa gccatcgccg tgttaacctc
tggtggagat gcccaaggta tgaatgctgc
121 tgtcagggct gtggttcgag tgggtatctt
tactggtgcc cgtgtcttct ttgtccatga
181 gggttaccaa ggcctggtgg atggtggaga
tcacatcagg gaagccacct gggagagcgt
241 ttcgatgatg cttcagctgg gtggcacagt
cattggaagt gcccggtgta aggattttcg
301 ggaacgagag gggcgacttc gagctgccca
caacctagtg aaacgtggga tcaccaatct
361 gtgtgtcatc gggggtgatg gcagcctcac
tggggcggac accttccgtt ctgagtggag
421 tgacttgctg agtgacctcc agaaagcggg
taagatcaca gcggaggagg ctacgaagtc
481 cagctacctg aatatcgtgg gcttggtggg
ctcaattgac aatgactttt gcggcactga
541 catgaccatc ggcaccgact ctgccctgca
ccggatcata gagatcgtgg atgccatcac
601 cactactgct cagagccacc agaggacgtt
tgtgttggaa gtgatgggcc ggcactgtgg
661 atacctggcc cttgtcacct ccctctcctg
tggggctgac tgggttttta ttcctgaatg
721 tccgccagat gatgactggg aggaacatct
ttgtcgccgg cttagtgaga caaggacccg
781 gggttctcgt ctcaacatca tcattgtggc
tgagggtgcg attgacaaga atgggaaacc
841 aatcacctca gaagaaatca aggagctggt
ggtaaagcgt ctgggatatg acactcgggt
901 cactgtcttg gggcatgtgc agcggggtgg
gaccccatca gccttcgacc gaatcctggg
961 cagcaggatg ggtgtggaag cagtgatggc
gctcttggag gggaccccgg acaccccggc
1021 ctgcgtggtg agcctctctg gtaaccaggc tgtgcgcctg
cccctcatgg agtgtgtaca
1081 ggtgaccaag gatgtgacca aggccatgaa tgacaggaaa
ttcgatgaag ccatgaagct
1141 gagaggccgg agcttcatga acaactggga ggtgtacaag
cttctggctc acatcagacc
1201 tcccgtctcg aagacatcgg ctaccatgca cacggtggcc
gtgatgaacg tgggtgcccc
1261 agccgcaggc atgaatgctg ccgtccgctc caccgtgaga
attggactca tccagggcaa
1321 ccgggtgctg gttgtgcatg atggcttcga gggcctggcc
aagggtcaga tcgaggaggc
1381 tggctggagc tatgtggggg gctggactgg ccaaggcggt
tccaaacttg ggactaagag
1441 gactctgccc aagaagagct ttgagcagat cagtgccaac
atcactaagt ttaacattca
1501 gggcctgatc atcatcgggg gctttgaggc ttacactggg
ggcctggagc tgatggaggg
1561 caggaagcag tttgatgagc tgtgcatccc gtttgtggtc
atccctgcta cggtgtccaa
1621 caacgtccct ggctcggact tcagcgtggg cgctgacaca
gccctcaaca ctatctgcac
1681 gacctgtgac cgcatcaagc agtcagcagc aggcaccaag
cggcgggtgt tcatcattga
1741 aactatgggt ggctactgcg gctacctggc caccatggca
ggcctggccg ctggggcgga
1801 tgctgcctac atttttgagg agcccttcac cattcgggac
ctgcaggcaa atgttgaaca
1861 tctggtgcaa aagatgaaaa caactgtgaa gaggggcctg
gtgttaagga atgagaagtg
1921 caatgagaac tataccacgg acttcatttt caacctgtac
tctgaggagg ggaagggcat
1981 cttcgacagc aggaagaatg tgctcggcca catgcagcag
ggtgggagcc caactccatt
2041 tgataggaat tttgccacta agatgggcgc caaggctatg
aactggatgt ctgggaaaat
2101 caaagagagt taccgtaatg ggaggatctt tgccaatacg
ccagactcgg gctgtgttct
2161 ggggatgcgt aagagggctc tggtctttca accagtgact
gagctgaagg accagacaga
2221 ttttgatcac cgcatcccca aggaacagtg gtggctgaag
ctgaggccca tcctcaaaat
2281 cctagccaag tacgagattg acttggacac cacagagcac
gcccacctgg agcacatcag
2341 tcggaagcga tctggagaaa cttctatcta accctctttg
gagtgagggt catggattgt
2401 ctgatcatgg tcagctcacc ccctgataga tccaagtcca
tgtatcccca agtattttag
2461 ctcatttttc tttaggtttc cttttattct gcaactgtag
ccatgaccag ctctggccag
2521 ggagctgggg cagcgggcag tgagtagagg ctccttttag
gtggaattta tcaacttcta
2581 ccccagcttc atctgtcaca caagactggg ctcctctagt
gctactgcta gatttcagct
2641 actcggttag aattttcctg aaaataagct ttatttattt
ctttgtgata acaaagtctt
2701 ggttcctcta ttacttttac tgcagtgaca aacaatagct
acactaataa atgccaactg
2761 gtcactgtga aaa
//