Drosophila melanogaster

LOCUS       DROPLC21B    5750 bp    mRNA            INV       18-JUL-1991
DEFINITION  D.melanogaster phospholipase C (plc-21) mRNA, complete cds.
ACCESSION   M60453
NID         g158132
KEYWORDS    phospholipase C.
SOURCE      D.melanogaster adult head, cDNA to mRNA.
  ORGANISM  Drosophila melanogaster
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Arthropoda;
            Tracheata; Insecta; Pterygota; Diptera; Brachycera; Muscomorpha;
            Ephydroidea; Drosophilidae; Drosophila.
REFERENCE   1  (bases 1 to 5750)
  AUTHORS   Shortridge,R.D., Yoon,J., Lending,C.R., Bloomquist,B.T.,
            Perdew,M.H. and Pak,W.L.
  TITLE     A Drosophila phospholipase C gene that is expressed in the central
            nervous system
  JOURNAL   J. Biol. Chem. 266, 12474-12480 (1991)
  MEDLINE   91286274
FEATURES             Location/Qualifiers
     source          1..5750
                     /organism="Drosophila melanogaster"
                     /db_xref="taxon:7227"
                     /dev_stage="adult"
                     /tissue_type="head"
     mRNA            1..5750
                     /gene="plc-21"
     gene            1..5750
                     /gene="plc-21"
     CDS             562..4500
                     /gene="plc-21"
                     /note="class II --> alternatively-spliced message"
                     /codon_start=1
                     /product="phospholipase C"
                     /db_xref="PID:g158133"
                     /translation="MMSAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVD
                     AKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLGPQDTLEEKTVT
                     VCHGSDFVNMTFVNFCCTRRDIAQLWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQ
                     VDKSGRIPVKNIIKLFAQNKEDRKRVEKALDVTGLPSGKVDSISVSKFQFEDFYNLYK
                     YLTQRSEVERLFDSIVGNSKRKCMSIAQLVEFLNKTQRDPRLNEILYPYANPARAKEL
                     IQQYEPNKFNAQKGQLSLDGFLRYLMGDDNPIMAPSKLDLCDDMDQPMSHYFINSSHN
                     TYLTGHQLTGKSSVEIYRQCLLAGCRCVELDFWNGRTEEPVIVHGYTFVPEIFAKDVL
                     EAIAESAFKTSEYPVILSFENHCNPRQQAKIANYCREIFGDMLLDKPLDSHPLEPNMD
                     LPPPAMLRRKIIIKNKKKHHHHHHHHHHKKPAQVGTPAANNKLTTANSVDAKAAQQVA
                     LSASHEDGGVTRSTANGDVATGTGTGSAAGTAGHAPPLQQIRQSSKDSTGSSDSDSSS
                     EDESLPNTTPNLPSGNEPPPEKAQKETEAGAEISALVNYVQPIHFSSFENAEKKNRCY
                     EMSSFDEKQATTLLKERPIEFVNYNKHQLSRVYPAGTRFDSSNFMPQLFWNAGCQLVA
                     LNFQTLDLAMQLNLGIFEYNARSGYLLKPEFMRRSDRRLDPFAESTVDGIIAGTVSIT
                     VLSGQFLTDKRANTFVEVDMYGLPADTVRKKFRTKTVRDNGMNPLYDEEPFVFKKVVL
                     PELASIRIAAYEEGGKLIGHRVLPVIGLCPGYRHVNLRSEVGQPIALASLFLCVVVKD
                     YVPDDLSNFAEALANPIKYQSELEKRDIQLSVLTDEAEALGSADEDLSKSCGQKKELR
                     PVESLATSPKHRPSISAAAAMSVDVTVDRTDGGRGEDSISIVAPSIQHQHSLDQSVST
                     SIRQVESSQFDVDLVLAEPLEKILDHKSVKEKRLEMEKKLESLRKKHDKEKIKIAGQK
                     SSPLEGKKPKFAITNKLVKRLSNKSLNCLSPHSEPGVEIPACPLDLGDSSEESAAADA
                     GEDLAGGSSSLDGRTQESRLRSACREYTSQYRELQEKYHEAIYSAAEKVLKTSQTGQT
                     KQLKASLDKVTGEVMHQLQEARRNEVKNLATVHRDRDELIRMKREVASSVVERGVAER
                     VRLKQTFDRRTDELQKQHDSVRNALAEHRSKARQILDKEAESRSCVSSNGFLVLFHGP
                     HHHGCTGSGSSALSGNNLTLNLDAGAAGSHSAISPAKSHNSIAAAAEMKT"
     exon            3729..3749
                     /gene="plc-21"
                     /note="alternate"
BASE COUNT     1592 a   1415 c   1416 g   1327 t
ORIGIN      chromosome band location 21C1.
        1 ggaaccctct ccgggtcccc agaatccgta tccgtatctg cagcagccga gtgcgtgtgt
       61 gtttctccgt atctgtgcgt tgtgactaag ccgacagtta aaaactatag ctaaactaaa
      121 ataggagagc gaatccaata aaaaatccca ttaccaccgg agaggttatc ttcgtttgcc
      181 agcgggtgca aaatctgaaa ttgaaatttc gctgcttacg aaatacaaat tccactcaac
      241 gaagttttca tctgaaagtc aaaaactttg gcacagaaaa cagccagaac ttttaatcag
      301 tcccagaatg cagtccaaag agctcgcatg cggtgcaaag tcaataccgc tctaacgtgt
      361 ccaggaccat gtcgatgatt cggataccaa ccaggactat ggcgtcattt gtatgcggtg
      421 tggctattct gcgacaacta agggaaagga aatgaggagc cgcggctaat ccaagaatcg
      481 cacagaaagt aaacagaaag cgttcatcag tgggtcagta gcagcccgta aacgagattt
      541 taaacccaaa aatttgtgag gatgatgagc gccggaggaa cctacatctc caccgccagc
      601 gtggaggtgc cacaagctct gcaagatggc gagaagttca ttcgatggga tgatgactcg
      661 ggcactggaa caccggttac aatgcgcgtc gatgccaagg gcttcttcct ctactgggtc
      721 gaccagaaca acgagctgga tatccttgat atagccacca tacgcgacgt tcgcacagga
      781 cagtacgcta agcgaccaaa ggacaacaag ctgcgccaga ttgtgacgct gggcccccag
      841 gacacgctcg aggagaagac agtgacggta tgccacggct cggacttcgt caacatgacg
      901 ttcgtcaact tctgctgcac ccggcgggac atagcccagc tctggaccga cggactcatc
      961 aagttggcct acagcttggc ccagctcaat ggctcggcga ttatgttcct gcagaaggcc
     1021 cataccaaac tgtgtctcca ggtggacaaa agcggccgca taccagtgaa aaacatcata
     1081 aaactttttg cccaaaacaa ggaggatcgc aaacgtgtcg agaaggcgct ggacgtgacc
     1141 ggtttgccgt cgggaaaggt cgatagcata tcggtgtcca aatttcaatt cgaggacttt
     1201 tacaatttgt acaaatatct cacgcagcgt tcggaggtag aacgcctctt tgacagcatc
     1261 gttggcaact cgaagcgcaa gtgcatgtcc atcgctcaac tggtggagtt cctgaacaag
     1321 acacagcgtg atccccgcct gaacgagatc ctctaccctt atgcgaatcc cgcccgcgcc
     1381 aaggagctca tccagcaata tgagcccaac aagttcaacg cgcaaaaggg ccaactcagc
     1441 ctggatggct ttttgaggta cttaatgggc gacgacaatc ccatcatggc gcccagcaag
     1501 ctcgatctct gcgatgacat ggaccagccg atgtcgcact acttcatcaa ctcctcgcat
     1561 aacacctact tgacgggaca ccagctgacc ggcaagtcgt ccgtcgagat ttacaggcag
     1621 tgtctcctgg cgggatgcag atgcgttgag ctcgacttct ggaacggacg caccgaggag
     1681 ccagtcattg tccacggcta tacgttcgtg cccgagatat ttgccaagga cgtgctggag
     1741 gccatcgcag agagtgcatt taaaacatcc gaataccctg tgatattgag ctttgagaat
     1801 cactgcaacc ctaggcaaca ggcgaaaatt gccaactatt gtcgcgaaat atttggcgat
     1861 atgctgctcg ataagcctct agactctcat ccgctggagc cgaacatgga cttgccaccg
     1921 ccggcgatgc tgcgccgcaa gattataatc aagaacaaga agaagcatca ccaccaccat
     1981 caccatcatc accacaaaaa gccagcgcag gtgggcacgc cggcagccaa caacaaactg
     2041 actacagcga attcagtgga tgccaaggcg gcgcaacaag tcgctttgtc ggcctcgcat
     2101 gaggatgggg gcgtgaccag gagcaccgcc aacggtgacg ttgccactgg aacaggaacc
     2161 ggaagtgctg ctgggacagc aggacacgcg ccgccgttgc aacaaatccg ccaaagctcc
     2221 aaagacagca ctggatcctc cgattcggac agctcttcgg aggatgaatc cctgcctaac
     2281 accacgccca atttgcccag cggcaacgaa cctccgccag aaaaggctca aaaggaaacg
     2341 gaggcgggag cagagatttc agctttggtc aactatgttc agcccatcca ttttagctct
     2401 tttgagaatg cggaaaaaaa gaatcgatgc tacgaaatgt cttcgtttga tgaaaaacag
     2461 gcgacaacat tattgaagga gcgaccgatt gaatttgtga actacaacaa acaccaatta
     2521 tctcgtgtct atccggcggg cactcgcttt gatagctcca actttatgcc gcagttgttc
     2581 tggaatgccg gatgtcagct cgtggcactt aacttccaaa ccctcgatct ggccatgcaa
     2641 ctcaacttgg ggatctttga gtataacgct cggtccggtt atctacttaa gccggagttt
     2701 atgcgccgat cagatcgcag attggatccc ttcgcggaaa gcactgtgga tggcatcata
     2761 gcaggcacag tatcaatcac ggttctatct ggtcagtttc tcacggataa gagggcgaac
     2821 acttttgtgg aagttgatat gtacggtttg ccagcggaca cggtgagaaa gaagtttcgc
     2881 accaagacag tgcgggataa tggaatgaat cccctttatg acgaggagcc gttcgtgttt
     2941 aagaaggtgg ttctccccga gttggcgagc attcgaattg cagcatatga agagggtggc
     3001 aaactcattg gtcaccgcgt tttgcccgta atcggtcttt gccctggtta ccgacatgtg
     3061 aatctccgat ctgaagtggg tcaaccaata gcccttgcct ctcttttcct gtgcgtggtg
     3121 gtcaaggatt atgtacccga tgatctttcc aatttcgcag aggcgctagc taaccctatt
     3181 aaataccaaa gtgagctaga gaagcgcgat attcaactat ctgttttgac cgacgaagcc
     3241 gaagcgctgg gcagtgcgga cgaggatctc tccaagtcgt gtggccaaaa aaaggagctg
     3301 cgtccggttg aatcgcttgc gacttcgccg aagcataggc cgagcatctc ggccgccgca
     3361 gcaatgagtg ttgacgttac cgtggatcgg accgatggcg gaaggggaga agatagcatc
     3421 tctattgtag caccctcaat acagcatcag cactctctag accagtccgt aagcacctcc
     3481 atccgacagg tggagtcctc gcagtttgat gtcgatcttg tgttggcgga gccgctggaa
     3541 aagatattgg atcacaagtc cgtcaaggaa aagcgtctcg agatggaaaa gaagctggag
     3601 tcactgcgaa agaagcatga caaggaaaag attaagatcg ccggccagaa atccagtccg
     3661 ctagagggca agaagccgaa gtttgccatc acgaataagc tggtgaagcg gctaagcaac
     3721 aagagtctta attgtctttc tccgcacagc gagcctggtg tagagatccc cgcctgccct
     3781 ctggatctgg gcgatagcag cgaggagagt gcagccgcgg atgccggtga ggacttagcc
     3841 ggtgggagca gcagtctgga tggcagaact caagagtcgc gattacgcag tgcctgccgg
     3901 gagtacactt cccagtaccg tgagctgcag gagaagtacc atgaggcaat ttacagtgca
     3961 gccgagaagg tgctgaagac atcgcaaact gggcaaacaa agcagttaaa agcatctctg
     4021 gacaaggtca ctggagaggt tatgcaccag ctgcaggagg cccgccgcaa cgaggttaag
     4081 aatctggcca ccgtgcaccg ggatcgtgat gagctgatca gaatgaaacg cgaggtggca
     4141 agctccgttg tggaacgtgg cgtagctgaa cgtgtgcggc tgaagcagac ctttgaccgg
     4201 agaacggatg aacttcagaa gcagcacgac tcagtgcgca atgccctggc agagcaccgc
     4261 tccaaggctc gtcaaattct cgacaaggag gcagaatcgc gaagctgtgt atccagcaat
     4321 ggcttcttgg tcctcttcca tggacctcat caccatggct gtacgggctc cggctcgtca
     4381 gccctttcag gcaataatct cactctaaat ctggacgcgg gggctgccgg tagtcattca
     4441 gccatttcgc cggcaaagtc gcacaacagc atcgcagcag cggccgagat gaagacgtaa
     4501 atgggccacg ccgtataggt ttttctcccc gcccaaatta tccctaggat taattgtggt
     4561 tctaaagttg ttagtcttca gtatttacag cagaaacata ggaatgaaaa gtcttcgtag
     4621 tatataagca gtggaggagt agtccctatc ctcccacacc tatttgacgg gaactgacct
     4681 cgattagatc ttaggacctt tgaccctagg cattgtaaat cccactgcta aggggaatcc
     4741 aagcaaacac gttttctaac tgaacaaact agatgtaaat ctatcgcatg tatgatgtac
     4801 ttgtagcgta actgttgacg tatccgtact ttacagtact ttatctgtat actgaacggt
     4861 gtatttctat ggtgttaatg gaggttgatc catcacactc ccgtcaaacc gtacggtttc
     4921 ttcctattcg aacttcgctg aaactctgag tgtctaatta agcaagcaaa tgtaacagaa
     4981 gcagaaaata agtataattt atttgtctat acgaaggaga ctgagtgctc catttgtcta
     5041 atgctaattg tggttgtgtg tattttacat cagttttaat cgatataatt tatacaatta
     5101 gtttaagcct ctcacacaaa ctgtggattg aatctcgtgc gcacacaagg cggatgctag
     5161 agcggatgcc aaagcacaag tctaggccaa caattagtca tttatttctc ggttggttgc
     5221 tatttattct tgatttagtc actattctta cgtttaccta gtcgttacaa agctccaata
     5281 aaattctata cggattgttt ttccccactt atacctacac atattttact ttattcccaa
     5341 tttaattcgg tccaatgcat acacacacac gcacagacgg cgtcgcacat aacctacaac
     5401 accaaaaata acaaaatacg atcggcgatt ttgcagtttg cgggagctaa cataccgatc
     5461 cgggttaccc tgaaattgtc gacttgtgcc acattctcaa gacaatcaaa caataaaata
     5521 tgcaaattta ttgagtgtat ttaacctatg ttgtagacaa gacaccactc cttaggtaat
     5581 caaacaaaaa aaaaaaaatt tacttacatg taggacgagg aatttattac ggttcatata
     5641 aatttactcc aacttgatta attggagtaa ttattttatt tttagtaata ggaacagctt
     5701 ttataggata cgtattacct tgaggacaaa tatcattttg aggagctact