LOCUS MMCRKING
7854 bp DNA
ROD 06-NOV-1997
DEFINITION M.musculus gene for mitochondrial creatine kinase.
ACCESSION Z13969
NID g634057
KEYWORDS creatine kinase.
SOURCE house mouse.
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria;
Rodentia; Sciurognathi; Muridae; Murinae; Mus.
REFERENCE 1 (bases 1 to 6031)
AUTHORS Steeghs,K., Peters,W., Bruckwilder,M., Croes,H.,
Van Alewijk,D. and
Wieringa,B.
TITLE Mouse ubiquitous mitochondrial
creatine kinase: gene organization
and consequences from inactivation in mouse embryonic stem cells
JOURNAL DNA Cell Biol. 14 (6), 539-553 (1995)
MEDLINE 95322032
REFERENCE 2 (bases 1 to 7854)
AUTHORS Wieringa,B.
TITLE Direct Submission
JOURNAL Submitted (20-MAR-1992) Wieringa B., University
of Nijmegen,
Adelbertusplein 1, Nijmegen, The Netherlands
COMMENT On Jan 25, 1995 this sequence version
replaced gi:50559.
FEATURES
Location/Qualifiers
source
1..7854
/organism="Mus musculus"
/strain="F1 C57Bl6 x CBA"
/db_xref="taxon:10090"
/tissue_type="Spleen"
mRNA
join(<2363..2723,3308..3506,3674..3769,4265..4486,
4611..4696,4815..4938,6218..6352,6518..6643,7038..7276)
/product="creatine kinase isoenzyme, ubiquitous"
exon
<2363..2723
/number=1
5'UTR
<2363..2571
sig_peptide 2572..2688
CDS
join(2572..2723,3308..3506,3674..3769,4265..4486,
4611..4696,4815..4938,6218..6352,6518..6643,7038..7154)
/EC_number="2.7.3.2"
/function="Creatine phosphate energy shunt"
/codon_start=1
/product="creatine kinase isoenzyme, ubiquitous"
/db_xref="PID:e1172459"
/db_xref="PID:g663017"
/db_xref="MGD:MGI:99441"
/db_xref="SWISS-PROT:P30275"
/translation="MAGPFSRLLSARPGLRLLALAGAGSLTAGILLRPESVGAAAAER
RRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPF
IKTVGMVAGDEETYEVFAELFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYV
LSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQ
QQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEK
GGNMKRVFERFCRGLKEVEKLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLP
LLSKDNRFPKILENLRLQKRGTGGVDTAATGSVFDISNLDRLGKSEVELVQLVIDGVN
YLIDCERRLERGQDIRIPPPLVHSKH"
mat_peptide join(2689..2723,3308..3506,3674..3769,4265..4486,
4611..4696,4815..4938,6218..6352,6518..6643,7038..7151)
/product="creatine kinase isoenzyme, ubiquitous"
exon
3308..3506
/number=2
exon
3674..3769
/number=3
exon
4265..4486
/number=4
exon
4611..4696
/number=5
exon
4815..4938
/number=6
exon
6218..6352
/number=7
exon
6518..6643
/number=8
exon
7038..7276
/number=9
3'UTR
7155..7276
polyA_signal 7253..7258
polyA_site 7277
BASE COUNT 2094 a 1839 c
1862 g 2050 t 9 others
ORIGIN
1 gaattcatca agggataaat
ccattaatta gagtagagcc cttttgagct ttttgcaata
61 gctggtaatt aaccaaaccc caatacatga
gccagtaaag aacatttctt atcgaaaaag
121 aattgatgat actgatgata tgaaagctta
tttacgcata tgttactgtt gaccttgaat
181 cttcatttag gagtttgagt gcccccattt
gttctctata attttgggaa cctaggaatt
241 gtcctagtta gatgcctcat cttactgaaa
cctctgcccc aggcttcctg aattgataga
301 gatagattct aagagcagaa tctacaaaga
atcagtgata gttagggctc agactcattc
361 ctcttctacc actccaaccc tgggagcgag
taattaccgc agctcccagc tgtaaacagc
421 ctccagcgac cccactggca tactgagcct
cacaaagaat ttaaaaagtg cacaaatcga
481 tgagccctct tggaagagct attgtttccc
ataggaaggc atttnccaaa tttgaatgac
541 ttctctgtac cctggctgcc tttacttctt
ctgttagcct ctcttcccac accccactcc
601 tgaacacctt ctcagccaaa taatagccca
attgctctcg aagactatct cctcctttta
661 tctgggtaaa tatcnccatc ccaagtaatt
atatcactta ctcatacctc nccttacctg
721 gatatgaaca cccacagcac aggtaacatt
ttttttccct ctccaaaaat aaggaagttc
781 caccagtaga tctctatctt ggaaaatgtg
ttatgttacc aagagaagag gcttaagtaa
841 tggagccaaa agtgaaatgg attctttcta
aggatacnca ccaatgagaa aggtcagaaa
901 ggagacatat ggggtgggga cttgagggaa
ataattaatg tatatagttg ggccagtggg
961 gattatgaag ggtaattctt tttcccaagt
actttcttac aacttccaaa tatcttactg
1021 tcttctggaa catcaggaag ctgaaggtag acatattaan
nncaatatgt ctgcttttgc
1081 tttggctggc cctccgcacc caaacctcag gtctctatct
cagcttcagc tttcattccc
1141 cttcccaata tgtctgcttt gctttggctg gccctccgca
cccaaacctc aggtctctat
1201 ctcagcttca gctttcattc cccttcctgc actaataaaa
gtcaagttgc tcctagccca
1261 gcacgtagct gtggaaacaa accctcttga gtctgagtat
gcacttcgca aaagagagag
1321 cggaccagga agaagacaga gactccctga tgaccttatg
cccttggata ctaccagcct
1381 tcacactcca gtttaaactg ccttagcaag ccaagagagg
aagcacgagt ggttcgggag
1441 acctgtgcct gcctgttcca ttccacaccc agtcatctca
ccagaccctc ctcctctctt
1501 tatattcccc ctccagtcct aggaactgcc agctgcagag
aagaaggaag agaaggaaga
1561 agaaactcac cattccctgc ccaaccccag ccccacaccc
agagcaatca acaggtaggc
1621 tttcagacac tactcaggaa gagtccttcg aacagcaaac
agatttaagc ctggaaaaga
1681 agaagagaaa taaaagatca aaggtgaagc aggggttaga
gtagaggaaa aaaagaaaaa
1741 aaaagcaggt ccccaatgag aggcaggaaa tagccaagct
gaagacttgg aggcagtgag
1801 tttgggagac aggattctta agggatcctt tctcgacctt
attaggaaag cataggtgta
1861 gctggagttc cctggtgctt cctggttctt agggaaggtg
acttgaggct gtgctgtctt
1921 tcccctgagc tcgctcagtc ttcctcctct atctgtttat
tctgtggttt tcctgcggct
1981 gactctcctg gggaaaatgg agagatggcg tgcagatcga
attcaattca gaaaagaggc
2041 tgggcaatgt caacctcccc acccccaccc ccaaaaccca
gaaatagacg gattggtttc
2101 agatttaaac agagagggta tgaaagaagg ggggtttcag
gttcgggaat ccccgtggtg
2161 ctgtcctcta cttagtgctg aaatctgaca ccctcatcct
tggtgggcgt ctgtctccag
2221 cctcagggag taaatctcca gtcttcttaa ttacctggct
agtgctaccc aaccccaccc
2281 ccgcacacct agcgcggtgg caggcgggaa ggcggagcct
gagtgagccc cacccctgga
2341 gactgcggct ggggcctccc tctgctctgg ctggctcctt
gcttcgctgc gcttctcctg
2401 cagcctggta ggcaccggct gccacttcag cttcagcctt
catcgtgacc cctattttgg
2461 ctccagtctc cgacccagct ccgtcctctc tctacccggt
tgcatcttcc ctcctagttc
2521 ctgacttgca ccagatcctg ctctgaatct ttgtagccgc
atccccaagc catggctggt
2581 cccttctccc gtctgctgtc tgcccgccct ggactcaggc
tcctggcttt ggctggagct
2641 gggtctctca ccgccgggat tctgctccgc ccggaatctg
taggagctgc cgctgctgaa
2701 cggaggagac tgtatccccc gaggtattag agcctgagat
gcacgaggtg ggggctgggg
2761 gtggtagtgg tggtgatggg aaccgaacag gtagagagga
taacctgagc aaaagatagg
2821 cctcgaagat ggatttcctg tacagtttgg agatcctagc
cctgtaatgg aagaacatgt
2881 ctaaggacat gtcacccgat gtcactgcct ccacaccagc
tttacctttg caaattctag
2941 gttcacccac tgcccaaatc ctttttggat gactagaagc
tttttttttt tttttttttt
3001 tttaatctcg acctattctc cttgttctcc cgaattctcc
tgagtctctc ccctccccca
3061 tctctaatgt tatgctcact agagaaaagc aactctgtag
acaaggggga attgaggtgt
3121 tagaactatt aggaaagaaa agaccctgga aatccctgaa
gagattatca agatttagcc
3181 tacctctaat tccccctcct tccaataagc aaagccagac
atggctcact ggacagctcc
3241 cagctgacat cagtaggtct aggctcctgt gccctccctc
catggttact gggtaccccc
3301 ttcccagcgc tgagtaccca gacctccgaa agcacaacaa
ctgcatggcc agtcacctga
3361 ccccagcagt ctatgcacgg ctctgcgaca agaccacacc
cactggttgg acactagatc
3421 agtgcatcca gactggagtg gacaaccctg gccacccctt
catcaagact gtgggcatgg
3481 tggctggaga tgaggagacc tatgaggtag ggggcccctc
agaaatccca gttccttcct
3541 cctaaagatc cctcatgtct gttccctcaa gactctggat
tgtctatact caaacgttct
3601 gatccagtga tatcaatcta caactcaagt gtttcttctt
tataatcgcc tcttcctctt
3661 aactcctttt caggtatttg ctgaactgtt tgaccctgtg
atccaagagc ggcataatgg
3721 atatgacccc agaacaatga agcacaccac tgaccttgat
gccagtaaag tgagccaaat
3781 gtgacacttc cgatatgtgc agccttgtgc acaatgttct
gtatctccaa tcattacacc
3841 ttgtttcctg actcagggtt agactgctga gctttgtata
ttgataagag aaagaattgc
3901 atatcttgaa gtatagcaga taggaggacg tagtggataa
gagtctggat aatggagttg
3961 aggagaatct gatcaaagta caaaatggtg aaagaatttt
taagaagtga ctatgtcctg
4021 gctgggtgtg gtggctcaca cctgtaatct cagctctcag
acggctcaga agagcactcc
4081 tccctccacc aaaaaaaaaa aaaaaaaggc tgtacccaaa
gtgagaaatg tggagaaatg
4141 accacagtgt tttcagttag catgcctgtc caatgtgtct
tccttctggc acctgcttta
4201 taatccccaa gagttcccac ctgctgtgtt tctatgattt
atagtcattt ctcttattcc
4261 tcagattcgt tctggctact ttgatgagag gtatgtattg
tcttcaagag tcagaactgg
4321 ccgaagtatc aggggactca gtctccctcc agcctgcact
cgggcagagc gaagagaggt
4381 agaacgtgtt gtggtggatg ctctgagtgg cctgaagggt
gacctggctg gacggtacta
4441 taggctcagt gagatgacgg aggccgaaca gcagcagctt
attgatgtga gggccttgac
4501 agggaacggg attgtggaaa aagaggtgga ggggagagtg
gaccagaaaa ggtagatggc
4561 ctggatggta ctgtgagaat tcttagaccc aatcccttta
ttctcctcag gaccattttc
4621 tgtttgataa acctgtgtcc ccattgctga ctgcagcagg
aatggctcga gactggcctg
4681 atgctcgagg gatctggtat ggagccaaca cacttttttg
gttttttttt tcccccttgt
4741 atgtgcaaag ttttttctcc atctacccca gtgcttgtct
tgcccactga tggctatacc
4801 tatcctgccc tcaggcacaa caatgagaag agtttcttga
tctgggtgaa tgaggaggac
4861 cacacacggg tcatctctat ggagaaaggc ggcaacatga
agagagtgtt tgaaagattc
4921 tgccggggcc tcaaagaggt tggagaaggg tataccaggg
agctagggga gaggaaatga
4981 gaaataccac acagcagcat agctagatcg gctatatcac
ttgtcagtca acccagagta
5041 tttctgatag tagaaagggt cattatcatg ctaggataat
agttacaaac cagggccgtc
5101 cttggnaaac cagggcatat agttactcta aaaatagaaa
gagtgtcagt aacctaagga
5161 aggaaataaa gcataatctt tgccaagtaa tgaaaagaag
gaaccaatga tcagcaagcc
5221 agtgccgggg taggtggtat gaggtagtat gtgcagttaa
ggagaacgtt tgagcctgga
5281 ctgatggaag gcgtgagaga ttggtttgtt catgatacat
caccaagttc tgancaaggc
5341 tcaccttggc tctggagatc tgatccttga tgtattttct
tgtatctaca gttttatttt
5401 tggacttgta aagaaagggt gcttctcttt tagattctag
ccaggaagct cacactattt
5461 tcggcaagga atggataatg ttctatgagt agcatagaga
aatactcttt aattatatga
5521 ctctgtttat ttgtctataa agttgaggac taaatgaaat
aatgtaggca gaggaattgt
5581 tctataataa gtgttagctt tacgatgtaa aaatctccat
gcttgtgatt ccttctgagt
5641 tacagagcat catctttagg tagtgtggtc tttgtgtcta
ttgctctggc aggcccctgt
5701 ctcttccatc ctaatagtca ttatggtggt caggaaagca
agaacatctc ttgaagtccc
5761 cctcttctca catgtacctg tgaatctggc ttctctgctg
taccttctca tgtctccctg
5821 ctctattatc catgttcctt ttatagctaa gagtaggctc
tcctgcctta gcacctcgtt
5881 tctgtccaaa gggacccttt gtcaaagatg taattgatgc
atgagaactc cctgtcctgt
5941 ttactacttc tattcatttc ccaagtcact cttaatgtat
cattctccaa agcttcttct
6001 acgaacaatc tatctgccac aatcttatca gcatgcatat
aatgcaacat ccaagtgtcc
6061 ttccatgtgc aatgacaata agttttaaca acaacaaaga
gcatgtcatt catcgatcgt
6121 caagtttctc gttgtagaca tagttctaga atgtctgtgg
ggctaagagg gatccctccc
6181 tccctgattt ttcacaacag aacctctgtt gacacaggtg
gagaagctga tccaggaacg
6241 aggctgggag ttcatgtgga atgagcgttt aggctacatc
ttgacctgtc catctaacct
6301 gggcactgga cttcgggcag gagtccacat caaactgcca
ctgctgagca aagtaaagga
6361 tatgtggggc tagagggggt gtaagaaggg ggacttggaa
gggggtggag gagacactct
6421 aaaaagagcc agtcctaagg gcttatggct agtgggccaa
gggtaggagc agtctcagaa
6481 actattgaca tgcccctgat ctttaccttg catctaggat
aaccgcttcc caaagatcct
6541 ggagaaccta agactgcaaa agcgtggaac tggaggagtg
gacactgctg ctacaggcag
6601 cgtctttgac atctctaatt tggatcgact tggcaagtca
gaggtgaggt cttatgaatc
6661 aggttaagag gttgagataa ggcagtgagt gagcctcagg
aacataatag aatctgaagc
6721 aatggtcagg ttgagtgggg tagggaagag aaaacgagtt
ttcagagatg gaagagctaa
6781 agaaactcag gtcaggcaag gtggtctgtg cttttaatac
cagcagaagc aagacagatc
6841 tctgtgagtc tcaggccagc cagggctaca taatgagatc
ctgtcacaaa aactgaaaaa
6901 agaaaaagaa ggaaaagaag gaaggaggga aggaaggaag
ggagagagag agagagggag
6961 ggagagagag gaagagagag agattaagag aagctcgggt
acaccgggaa gcagggatca
7021 aggactgtgt tcttcaggtg gagctggtgc agctcgtcat
cgatggggtg aactatttga
7081 ttgactgtga acggcgtctg gagagaggac aggatattcg
aatccctcca cctcttgtcc
7141 acagcaaaca ttaactcccc atccccagcg gatgagtcaa
gacccccagg acttctgcat
7201 atttaacagt ggcccagtct acttgccctg gacctgcctc
tctccctgtc ctagtaaaga
7261 ctccacatta tgttgcagct gtctgtgtta tttctattgg
tgtggtgagg aggaagtagg
7321 aaatgaaaag aaacagtgag gttattcatg atggcaagag
gcgtatatgc caggagcaca
7381 gttctcaggt gggtggaatg cattggaatt ttacccacaa
tcctcatcca cttactgaga
7441 ataattagta tgcacttcca tttacaagtt gttcagtatg
atgtaaattt tctccctcaa
7501 ctgaaggaac agttatcata ataggtggcc aaaaaaaatg
ctgacggggc aatgccaggg
7561 cccaggaggc ttggaaccag tcgtagagac cccaggctga
gtttcgacct agaatgagac
7621 aaggaatggg aggaaaaaaa atcacagttc cgttccccag
gagcctttga tgtttcaaat
7681 ttagctctgt gtatagatcc ctctactcca gagattctcc
tgtgtggggt ctgaggacca
7741 gacagcacca agttaggact tagatggact ctgggtcaga
tgacagctta tcaaactatg
7801 cagttggtaa cgtacccagc tgctctggga tctccttccc
ttcgtgttgg gccc
//