LOCUS       RRCKUM       1543 bp    mRNA            ROD       21-OCT-1991
DEFINITION  Rat mRNA for ubiquitous mitochondrial creatine kinase.
ACCESSION   X59737
NID         g57538
KEYWORDS    creatine kinase.
SOURCE      black rat.
  ORGANISM  Rattus rattus
            Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria;
            Rodentia; Sciurognathi; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1543)
  AUTHORS   Payne,R.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JUN-1991) R.M. Payne, Washington Univ School of
            Medicine, 400 South Kingshighway Box 8116, Dept of Pediatrics, St
            Louis MO 63110, USA
REFERENCE   2  (bases 1 to 1543)
  AUTHORS   Payne,R.M., Haas,R.C. and Strauss,A.W.
  TITLE     Structural characterization and tissue-specific expression of the
            mRNAs encoding isoenzymes from two rat mitochondrial creatine
            kinase genes
  JOURNAL   Biochim. Biophys. Acta 1089 (3), 352-361 (1991)
  MEDLINE   91316135
FEATURES             Location/Qualifiers
     source          1..1543
                     /organism="Rattus rattus"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10117"
     mRNA            1..1543
                     /note="ubiquitous mitochondrial creatine kinase"
                     /evidence=experimental
     transit_peptide 110..226
                     /product="ubiquitous mitochondrial creatine kinase"
     CDS             110..1366
                     /EC_number="2.7.3.2"
                     /codon_start=1
                     /product="ubiquitous  mitochondrial creatine kinase"
                     /db_xref="PID:g57539"
                     /db_xref="SWISS-PROT:P25809"
                     /translation="MAGPFSRLLSARPGLKLLALAGAGSLAAGILLRPESVRAATGER
                     RRLYPPSAEYPDLRKHNNCMASHLTPAVYARLCDKTTPTGWTLDQCIQTGVDNPGHPF
                     IKTVGMVAGDEETYEVFAELFDPVIQERHNGYDPRTMKHTTDLDASKIRSGYFDERYV
                     LSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQ
                     QQLIDDHFLFDKPVSPLLTAAGMARDWPDARGIWHNNEKSFLIWVNEEDHTRVISMEK
                     GGNMKRVFERFCRGLKKVEKLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVKLP
                     LLSKDSRFPKILENLRLQKRGTGGVDTPATADVFDISNLDRLGKSEVELVQLVIDGVN
                     YLIDCERRLEKGQDIRIPPPLVHGKH"
     mat_peptide     227..1363
                     /product="ubiquitous mitochondrial creatine kinase"
BASE COUNT      397 a    419 c    408 g    319 t
ORIGIN
        1 cgtagaaact caccattccc tgcccaaccc cagccccaca cccagagcaa tcaacagttc
       61 cagatttgcg ccagatcctg ctccaaatcc ggtagccgca tcccaagcca tggctggtcc
      121 cttctcccgt ctgctgtctg cccgccccgg actcaagctc ctggctttgg ctggagctgg
      181 gtctctcgcc gccgggattc tgctccgtcc ggaatctgta cgagcggcca ccggtgaacg
      241 gaggagactg tatcccccga gcgctgagta cccagacctc cgaaagcaca acaactgcat
      301 ggccagtcac ctgaccccag cagtctatgc acggctctgc gacaagacca cacccactgg
      361 ctggacacta gatcagtgca tccagactgg agtggacaac cctggccacc ccttcatcaa
      421 gactgtgggc atggtggctg gagatgagga gacctatgag gtatttgccg aactgtttga
      481 ccctgtgatc caagagcggc ataatggata tgaccctaga acaatgaagc acaccactga
      541 ccttgatgcc agcaaaatcc gttctggcta ctttgatgag aggtacgtat tgtcctcaag
      601 agtcagaact ggccgaagta tcaggggact cagtctccct ccagcctgca ctcgggcaga
      661 gcgacgagag gtggagcgtg ttgtggtgga cgcgctgagt ggcctgaagg gcgacctggc
      721 tggacggtac tacaggctca gtgagatgac agaggctgag cagcagcagc ttattgacga
      781 ccatttcctg tttgataaac ctgtgtcccc attgctgaca gcagcaggca tggctcgaga
      841 ctggccagat gcccgaggaa tctggcacaa caatgagaag agtttcttga tctgggtgaa
      901 tgaggaggac cacacacggg tcatctctat ggagaaaggc ggcaacatga agagagtgtt
      961 tgaaagattc tgccggggcc tcaaaaaggt ggagaagctg atccaggaac gaggctggga
     1021 gttcatgtgg aatgagcgtt taggatacat cttgacctgt ccatctaacc tgggcactgg
     1081 acttcgggca ggagtacacg tcaaactgcc actgctaagc aaagatagcc gcttcccaaa
     1141 gatcctggag aacctaaggc tgcaaaagcg tgggactgga ggagtggaca cgcctgccac
     1201 agcggatgtc tttgacatct ctaatctgga tcgacttggc aagtcagagg tggagctggt
     1261 gcagctggtc atcgatgggg tgaactattt gattgactgt gaacggcgtc tggagaaagg
     1321 acaggatatt cgaatccctc cacctcttgt ccacggcaaa cattaactcc ccgtccccag
     1381 cagctgaatc aagattcccc aggacttctg catatttaac agtggcccat tctacttgcc
     1441 aaggacctgc ctctcaatcc ctgtcctagt aaagactcca cgttctgttg caaaaaaaaa
     1501 aaaaaataaa gttcctattt ctctgcaaaa aaaaaaaaaa aaa
//