Alcohol Dehydrogenase

    Alcohol Dehydrogenase (ADH) is a protein in the oxidoreductase class of enzymes.  ADH is capable of interconverting ethanol and acetaldehyde in the presence of NADH as shown below.

It is ADH that allows yeast to produce many of the alcoholic beverages that people over 21 enjoy.  It is also the enzyme responsible for the oxidization of this alcohol in the liver.

    View the RasMol image of Alcohol Dehydrogenase (If you can't view the ADH image you need RasMol)

    Alcohol Dehydrogenase has been sequenced in many different species.  Listed below are sequences from GenBank searching.

    Homo sapiens                   amino acid sequence, mRNA sequence
    Mus musculus                   amino acid sequence, mRNA sequence
    Drosophila melanogaster    amino acid sequence, gene sequence
    Caenorhabditis elegans      amino acid sequence, mRNA sequence
    Arabidopsis thaliana          amino acid sequence, mRNA sequence

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