SOURCE      house mouse.
  ORGANISM  Mus musculus
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae;
            Murinae; Mus

LOCUS       MUSHEXOKB    3071 bp    mRNA            ROD       16-JUL-1997
DEFINITION  Mus musculus hexokinase (Hk-1) mRNA, complete cds.
ACCESSION   L16949
NID         g309292
KEYWORDS    hexokinase.
SOURCE      house mouse.
  ORGANISM  Mus musculus
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae;
            Murinae; Mus.
REFERENCE   1  (bases 1 to 3071)
  AUTHORS   Mori,C., Welch,J.E., Fulcher,K.D., O'Brien,D.A. and Eddy,E.M.
  TITLE     Unique hexokinase messenger ribonucleic acids lacking the
            porin-binding domain are developmentally expressed in mouse
            spermatogenic cells
  JOURNAL   Biol. Reprod. 49 (2), 191-203 (1993)
  MEDLINE   93385326
COMMENT     *Reference [1] reports bases 1 through 286;  updated sequence to
            concur with publication, NCBI: 25-FEB-1997.
FEATURES             Location/Qualifiers
     source          1..3071
                     /organism="Mus musculus"
                     /strain="CD-1"
                     /db_xref="taxon:10090"
                     /clone="Hk1-sb"
                     /cell_type="germ cell"
                     /dev_stage="gamete"
                     /tissue_type="testis"
     mRNA            1..3071
                     /gene="Hk-1"
                     /evidence=experimental
     5'UTR           <1..187
                     /gene="Hk-1"
     gene            1..3071
                     /gene="Hk-1"
     misc_feature    1..117
                     /gene="Hk-1"
                     /note="unique region"
                     /evidence=experimental
     misc_feature    118..257
                     /gene="Hk-1"
                     /note="region shared with L16948 and L16950"
                     /evidence=experimental
     CDS             188..3025
                     /gene="Hk-1"
                     /EC_number="2.7.1.1"
                     /codon_start=1
                     /evidence=experimental
                     /product="hexokinase"
                     /db_xref="PID:g1850140"
 translation="MGQNCQRGQAVDVEPKIRPPLTEEKIDKYLYAMRLSDEILIDIL
                     TRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVN
                     HEKSQNVSMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSF
                     PCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTM
                     MTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLED
                     IRTEFDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKESLLFEGRITPELLT
                     RGKFTTSDVAAIETGWELSPDRRWYQAYMRCTQDTHRDKEGVQNAKEILTRLGVEPSH
                     DDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKMHPQY
                     SRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLSHFRLSK
                     QALMEVKKKLRSEMEMGLRKETNSRATVKMLPSYVRSIPDGTEHGDFLALDLGGTNFR
                     VLLVKIRSGKKRTVEMHNKIYSIPLEIMQGTGDELFDHIVSCISDFLDYMGIKGPRMP
                     LGFTFSFPCKQTSLDCGILITWTKGFKATDCVGHDVATLLRDAVKRREEFDLDVVAVV
                     NDTVGTMMTCAYEEPSCEIGLIVGTGSNACYMEEMKNVEMVEGNQGQMCINMEWGAFG
                     DNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQ
                     ISEPLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKR
                     AAQLCGAGMAAVVQKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCT
                     VSFLLSEDGSGKGAALITAVGVRLRGDPTNA"
     misc_feature    258..1232
                     /gene="Hk-1"
                     /note="Hk1 sequence"
                     /evidence=experimental
     misc_feature    1233..1301
                     /gene="Hk-1"
                     /note="unique region"
                     /evidence=experimental
     misc_feature    1302..3071
                     /gene="Hk-1"
                     /note="Hk1 sequence"
                     /evidence=experimental
     3'UTR           3026..3071
                     /gene="Hk-1"
                     /evidence=experimental
BASE COUNT      783 a    789 c    890 g    609 t

ORIGIN  
        1 ccttaacacc tgggaccatg gagggccccc ctcttctcaa ggcttgctag gttagaccag
       61 taactacatc aaggactcca acccaccagc tagagaccgt tcctcagaca cctgagaagg
      121 atcagaaaac cccgcttctg aggacagaag acctctggaa aaacagtgta gccatcacct
      181 ctacactatg ggacagaact gccagcgagg acaggctgta gatgttgaac caaaaatacg
      241 accccctctc acagaggaaa agattgataa gtatctgtat gccatgcggc tctctgatga
      301 aattctgata gatatcctga cacgcttcaa gaaagagatg aagaatggcc tctcccggga
      361 ttataaccca acggcctccg tcaagatgct gccaaccttt gtccggtcca ttccggacgg
      421 ctcagaaaag ggggatttca ttgcactgga tctcggcggg tcttcctttc gaatcctgcg
      481 ggtgcaggtg aaccacgaga agagtcagaa cgtcagcatg gagtctgagg tctacgacac
      541 cccagagaac atcgtgcacg gcagtggaag ccagcttttt gatcacgtcg ctgaatgcct
      601 cggagacttc atggagaaaa ggaagatcaa ggacaagaaa ttacccgtgg gattcacgtt
      661 ttccttcccg tgccgacaat ccaaaataga cgaggccgta ctgatcacgt ggacaaagcg
      721 gttcaaagcc agtggcgtgg aaggggcgga tgtggtcaag ctgctgaata aagccattaa
      781 gaagcgaggg gactatgacg ctaacattgt agctgtggtg aatgacacag tggggaccat
      841 gatgacctgc ggctacgatg accaacagtg tgaagtcggc ctgatcattg gcactggcac
      901 caatgcttgc tacatggagg aactgcgaca catcgacctg gtggaaggcg atgaggggag
      961 gatgtgtatt aacacggaat ggggagcctt tggggatgat gggtccctgg aagacattcg
     1021 aacagagttt gacagagagt tagaccgggg atccctcaac cctgggaaac agctgttcga
     1081 gaagatggtg agcggcatgt acatggggga gctggtccgg ctgatcctgg tgaagatggc
     1141 caaggaaagc ctcttatttg aagggcgcat tactccagag ctgctcacga ggggcaagtt
     1201 caccactagc gacgtagccg ccattgaaac gggatgggaa ctctcccctg accgcaggtg
     1261 gtaccaggca tatatgaggt gcacacaaga cacccacagg gataaggaag gcgttcaaaa
     1321 tgccaaggaa atcttgaccc gcctgggagt ggagccgtct cacgatgact gcgtatcggt
     1381 ccagcacgta tgcacgatcg tctccttccg atcagccaac ctggtggctg ccacgctcgg
     1441 tgccatcttg aaccgcctgc gggacaataa gggcacgccc aggctgcgga ccacagttgg
     1501 cgtagacggt tctctctaca agatgcaccc acagtattcc cggcggttcc acaagaccct
     1561 gaggcgcctg gtgcctgact cggacgtccg gttcctcctc tcggagagtg gcagtggcaa
     1621 gggagccgcc atggtgaccg ctgtggccta ccgcctggcc gagcagcacc ggcagattga
     1681 ggaaaccctg tcccacttcc gcctcagcaa gcaggcactg atggaggtga agaagaagct
     1741 gcggtcagag atggaaatgg ggctgagaaa ggagaccaac agcagagcta cggtcaaaat
     1801 gctgccttct tatgtgcgga gcatcccaga tgggactgag catggtgact tcctggcctt
     1861 ggatctcgga ggaacgaatt tccgagtcct actggtaaag atccgtagtg ggaaaaagag
     1921 aacagtggag atgcacaaca agatctactc cattcccctg gaaatcatgc agggcaccgg
     1981 ggatgagctg tttgatcaca ttgtctcctg catctccgac ttcctggact acatggggat
     2041 caaaggcccc cggatgcctc tgggcttcac cttctcgttt ccctgcaagc agacgagcct
     2101 agattgcgga atcttgatca cgtggacaaa gggattcaaa gccaccgact gtgtgggtca
     2161 cgatgtagcc actttactga gggatgctgt aaaaaggaga gaggaatttg acctggatgt
     2221 ggtggctgtg gtcaacgaca ccgtgggcac catgatgact tgtgcttatg aagaaccttc
     2281 ttgtgagatt ggactcatcg tggggactgg cagcaatgcc tgctacatgg aggagatgaa
     2341 aaacgtggag atggtggagg ggaaccaggg ccagatgtgc atcaatatgg aatggggtgc
     2401 ctttggtgac aacggctgtc tggacgacat cagaacagac ttcgacaaag tggtggacga
     2461 atattctcta aacagtggga aacaaaggtt tgagaagatg atcagtggaa tgtacctggg
     2521 tgagatcgtc cgtaacatcc tgattgactt caccaagaaa ggcttcctct tccggggaca
     2581 gatctctgag ccactcaaga cccgaggcat cttcgagacc aagtttctct ctcagatcga
     2641 gagtgaccga ttagcgctgc tccaggtgcg ggccatcctt cagcagctgg gtctaaacag
     2701 cacgtgcgac gacagtatcc tggtcaagac cgtgtgtggg gtggtgtcca agcgggcggc
     2761 ccagctgtgt ggtgccggca tggccgccgt ggtgcaaaag atccgagaga acagaggcct
     2821 agaccacctg aatgtaaccg tgggcgtgga cgggacgctc tacaaactcc atccacactt
     2881 ctccagaatc atgcaccaaa cagtgaagga actgtcacca aagtgtaccg tgtccttcct
     2941 cctgtctgaa gacggcagcg gcaagggggc cgcccttatc acagctgtgg gcgtgcggct
     3001 cagaggagac cctacgaacg cctaagagca ggatcctccc agcccccagc ccgccaccct
     3061 tccagcactc c