LOCUS HUMLIGAA 3083 bp mRNA PRI 07-JAN-1995

DEFINITION Human DNA ligase I mRNA, complete cds.

ACCESSION M36067 NID g187142

KEYWORDS DNA ligase I.

SOURCE Human T lymphoblast cell line Jurkat, cDNA to mRNA.

ORGANISM Homo sapiens Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata; Vertebrata; Eutheria; Primates; Catarrhini; Hominidae; Homo.

REFERENCE 1 (bases 1 to 3083)

AUTHORS Barnes,D.E., Johnston,L.H., Kodama,K., Tomkinson,A.E., Lasko,D.D. and Lindahl,T.

TITLE Human DNA ligase I cDNA: cloning and functional expression in Saccharomyces cerevisiae

JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87 (17), 6679-6683 (1990) MEDLINE 90370849 COMMENT Draft entry and computer-readable sequence for [1] kindly submitted by D.E.Barnes, 03-JUL-1990.

FEATURES Location/Qualifiers source 1..3083 /organism="Homo sapiens" /db_xref="taxon:9606" /map="19q13.3" mRNA <1..3083 /note="DNA ligase I" gene 121..2880 /gene="LIG1" CDS 121..2880 /gene="LIG1" /note="DNA ligase I" /codon_start=1 /db_xref="GDB:G00-127-274" /db_xref="PID:g187143"

translation="MQRSIMSFFHPKKEGKAKKPEKEASNSSRETEPPPKAALKEWNG VVSESDSPVKRPGRKAARVLGSEGEEEDEALSPAKGQKPALDCSQVSPPRPATSPENN ASLSDTSPMDSSPSGIPKRRTARKQLPKRTIQEVLEEQSEDEDREAKRKKEEEEEETP KESLTEAEVATEKEGEDGDQPTTPPKPLKTSKAETPTESVSEPEVATKQELQEEEEQT KPPRRAPKTLSSFFTPRKPAVKKEVKEEEPGAPGKEGAAEGPLDPSGYNPAKNNYHPV EDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLS LNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRL MLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRL RLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFC EVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCE YKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVA WDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLL RENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSH NWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGT GFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYP AARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSD PEDTY"

polyA_signal 3062..3067 BASE COUNT 716 a 882 c 962 g 523 t ORIGIN Chromosome 19. 1 cagaggcgcg cctggcggat ctgagtgtgt tgcccgggca gcggcgcgcg ggaccaacgc 61 aaggagcagc tgacagacga agaaaagtgc tggacaggaa gggagaattc tgacgccaac 121 atgcagcgaa gtatcatgtc atttttccac cccaagaaag agggtaaagc aaagaagcct 181 gagaaggagg catccaatag cagcagagag acggagcccc ctccaaaggc ggcactgaag 241 gagtggaatg gagtggtgtc cgagagtgac tctccggtga agaggccagg gaggaaggcg 301 gcccgggtcc tgggcagcga aggggaagag gaggatgaag cccttagccc tgctaaaggc 361 cagaagcctg ccctggactg ctcacaggtc tccccgcccc gtcctgccac atctcctgag 421 aacaatgctt ccctctctga cacctctccc atggacagtt ccccatcagg gattccgaag 481 cgtcgcacag ctcggaagca gctcccgaaa cggaccattc aggaagtcct ggaagagcag 541 agtgaggacg aggacagaga agccaagagg aagaaggagg aggaagaaga ggagaccccg 601 aaagaaagcc tcacagaggc tgaagtggca acagagaagg aaggagaaga cggggaccag 661 cccaccacgc ctcccaagcc cctaaagacc tccaaagcag agaccccgac ggaaagcgtt 721 tcagagcctg aggtggccac gaagcaggaa ctgcaggagg aggaagagca gaccaagcct 781 ccccgcagag ctcccaagac gctcagcagc ttcttcaccc cccggaagcc agcagtcaaa 841 aaagaagtga aggaagagga gccaggggct ccaggaaagg agggagctgc tgagggaccc 901 ctggatccat ctggttacaa tcctgccaag aacaactatc atcccgtgga agatgcctgc 961 tggaaaccgg gccagaaggt tccttacctg gctgtggccc ggacgtttga gaagatcgag 1021 gaggtgtctg ctcggctccg gatggtggag acgctgagca acttgctgcg ctccgtggtg 1081 gccctgtcgc ctccagacct cctccctgtc ctctacctca gcctcaacca ccttgggcca 1141 ccccagcagg gcctggagct tggcgtgggt gatggtgtcc ttctcaaggc agtggcccag 1201 gccacaggtc ggcagctgga gtccgtccgg gctgaggcag ccgagaaagg cgacgtgggg 1261 ctggtggccg agaacagccg cagcacccag aggctcatgc tgccaccacc tccgctcact 1321 gcctccgggg tcttcagcaa gttccgcgac atcgccaggc tcactggcag tgcttccaca 1381 gccaagaaga tagacatcat caaaggcctc tttgtggcct gccgccactc agaagcccgg 1441 ttcatcgcta ggtccctgag cggacggctg cgccttgggc tggcagagca gtcggtgctg 1501 gctgccctct cccaggcagt gagcctcacg cccccgggcc aagaattccc accagccatg 1561 gtggatgctg ggaagggcaa gacagcagag gccagaaaga cgtggctgga ggagcaaggc 1621 atgatcctga agcagacgtt ctgcgaggtt cccgacctgg accgaattat ccccgtgctg 1681 ctggagcacg gcctggaacg tctcccggag cactgcaagc tgagcccagg gattcccctg 1741 aaaccaatgt tggcccatcc cacccggggc atcagcgagg tcctgaaacg ctttgaggag 1801 gcagctttca cctgcgaata caaatatgac gggcagaggg cacagatcca cgccctggaa 1861 ggcggggagg tgaagatctt cagcaggaat caggaagaca acactgggaa gtacccggac 1921 atcatcagcc gcatccccaa gattaaactc ccatcggtca catccttcat cctggacacc 1981 gaagccgtgg cttgggaccg ggaaaagaag cagatccagc cattccaagt gctcaccacc 2041 cgcaaacgca aggaggtgga tgcgtctgag atccaggtgc aggtgtgttt gtacgccttc 2101 gacctcatct acctcaatgg agagtccctg gtacgtgagc ccctttcccg gcgccggcag 2161 ctgctccggg agaactttgt ggagacagag ggcgagtttg tcttcgccac ctccctggac 2221 accaaggaca tcgagcagat cgccgagttc ctggagcagt cagtgaaaga ctcctgcgag 2281 gggctgatgg tgaagaccct ggatgttgat gccacctacg agatcgccaa gagatcgcac 2341 aactggctca agctgaagaa ggactacctt gatggcgtgg gtgacaccct ggacctggtg 2401 gtgatcggcg cctacctggg ccgggggaag cgggccggcc ggtacggggg cttcctgctg 2461 gcctcctacg acgaggacag tgaggagctg caggccatat gcaagcttgg aactggcttc 2521 agtgatgagg agctggagga gcatcaccag agcctcaagg cgctggtgct gcccagccca 2581 cgcccttacg tgcggataga tggcgctgtg attcccgacc actggctgga ccccagcgct 2641 gtgtgggagg tgaagtgcgc tgacctctcc ctctctccca tctaccctgc tgcgcggggc 2701 ctggtggata gtgacaaggg catctccctt cgcttccctc ggtttattcg agtccgtgaa 2761 gacaagcagc cggagcaggc caccaccagt gctcaggtgg cctgtttgta ccggaagcaa 2821 agtcagattc agaaccaaca aggcgaggac tcaggctctg accctgaaga tacctactaa 2881 gccctcgccc tcctagggcc tgggtacagg gcatgagttg gacggacccc agggttatta 2941 ttgcctttgc tttttagcaa atctgctgtg gcaggctgtg gattttgaga gtcaggggag 3001 gggtgtgtgt gtgagggggt ggcttactcc ggagtctggg attcatcccg tcatttcttt 3061 caataaataa ttattggata gct //
 

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