LOCUS AF047542
1836 bp mRNA
ROD 10-FEB-1999
DEFINITION Mus musculus cytochrome P450 (Cyp2c37) mRNA, complete
cds.
ACCESSION AF047542
NID g4249588
KEYWORDS .
SOURCE house mouse.
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria;
Rodentia; Sciurognathi; Muridae; Murinae; Mus.
REFERENCE 1 (bases 1 to 1836)
AUTHORS Luo,G., Zeldin,D.C., Blaisdell,J.A., Hodgson,E.
and Goldstein,J.A.
TITLE Cloning and expression of murine
CYP2Cs and their ability to
metabolize arachidonic acid
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1836)
AUTHORS Luo,G. and Goldstein,J.A.
TITLE Direct Submission
JOURNAL Submitted (10-FEB-1998) Laboratory of Pharmacology
and Chemistry,
National Institute of Environmental Health Sciences, PO Box 12233,
111 Alexander Drive, Research Triangle Park, NC 27709, USA
FEATURES
Location/Qualifiers
source
1..1836
/organism="Mus musculus"
/strain="CD-1"
/db_xref="taxon:10090"
/tissue_type="liver"
gene
1..1836
/gene="Cyp2c37"
CDS
1..1473
/gene="Cyp2c37"
/function="metabolizes arachidonic acid"
/note="drug metabolizing enzyme; CYP2C37"
/codon_start=1
/product="cytochrome P450"
/db_xref="PID:g4249589"
/translation="MDPILVLVLTLSCLFLLSLWRQSSERGKLPPGPTPLPIIGNILQ
IDVKDICQSFTNLSKVYGPVYTLYLGRKPTVVLHGYEAVKEALVDHGEEFAGRGRFPV
FDKATNGMGLAFSKGNVWKNTRRFSLMTLRNLGMGKRSIEDRVQEEARCLVEELRKTN
GSPCDPTFILGCAPCNVICSIIFQDRFDYKDRDFLNLMEKLNEITKILSSPWLQICNT
YPALLDYCPGSHKQFFKNYACIKNFLLEKIKEHEESLDVTIPRDFIDYFLINGGQEDG
NQPLQNRLEHLAITVTDLFSAGTETTSTTLRYALLLLLKYPHVTAKVQKEIEHVIGKH
RSPCMQDRSRMPYTDAMIHEVQRFIDLIPNSLPHEVTCDIKFRNYFIPKGTTVITSLS
SVLHDSTEFPNPEVFDPGHFLDGNGKFKKSDYFMPFSTGKRICAGEGLARMELFLFLT
SILQSFNLKPLVHPKDIDVTPMLIGLGSVPPAFQLCFIPS"
polyA_signal 1787..1792
/gene="Cyp2c37"
/note="putative"
polyA_site 1808
/gene="Cyp2c37"
BASE COUNT 532 a 412
c 372 g 520 t
ORIGIN
1 atggatccaa tcctggtcct
ggtgctcact ctctcctgtc tgtttctcct ctcactctgg
61 agacagagct ctgaaagggg gaagctccct
cctggcccca ctcctcttcc aattattgga
121 aacatccttc agatagatgt gaaggacatc
tgccaatcct tcaccaattt atcaaaagtt
181 tatggccctg tgtatactct atatttgggc
aggaagccca ctgtggtgtt gcatggatat
241 gaggcagtga aggaagctct ggttgaccat
ggggaggagt ttgctggaag gggaaggttc
301 ccagtttttg ataaagctac taatggaatg
ggccttgcat ttagtaaagg aaatgtatgg
361 aaaaacacga ggcgtttctc actcatgacg
ctgcggaatt taggcatggg aaaaaggagc
421 attgaggacc gcgttcaaga agaagcacgt
tgccttgtgg aggaacttag gaaaaccaat
481 ggctcaccct gtgatcccac cttcatcctg
ggctgtgctc cctgcaatgt catctgctca
541 attattttcc aggatcgttt tgattataaa
gatcgggatt ttcttaactt gatggaaaaa
601 ctgaatgaaa taacaaagat tctgagcagc
ccttggttgc agatttgcaa tacatatcct
661 gctctgcttg attattgtcc aggaagtcat
aaacaatttt ttaaaaatta tgcttgtatt
721 aaaaatttcc ttttggagaa aataaaagaa
catgaagaat cattggatgt tacaattcct
781 cgtgacttta ttgattattt cctaattaat
ggaggccagg aagacggcaa tcaaccattg
841 caaaataggc ttgaacacct ggcaataaca
gtgactgatc ttttttctgc tgggacagag
901 acaacaagca caacactgag atatgctctc
ctactcctgt tgaagtaccc acatgtcaca
961 gctaaagtcc agaaagaaat tgagcatgtg
atcggcaagc accgaagccc ttgcatgcag
1021 gacaggagcc gcatgcccta tactgatgcc atgattcatg
aggtccagag attcattgac
1081 ctcatcccca acagccttcc ccatgaagtg acctgtgaca
ttaaattcag gaactacttc
1141 atccccaagg gaacaactgt aataacatca ctgtcatcag
tgctgcatga cagcacggag
1201 ttccccaacc cagaagtgtt tgaccctggc cactttctag
atgggaatgg aaagtttaag
1261 aaaagtgact atttcatgcc cttctcaaca gggaaacgga
tatgtgcagg agagggcctg
1321 gcacgcatgg agctgttcct gttcctaacc agcattttac
agagcttcaa cctgaaacct
1381 ctggttcacc caaaggacat agatgtaacc ccaatgctca
ttggattggg ctcagtgcct
1441 cctgctttcc agctctgctt cattccttcc tgaaaatcaa
atgcctggct ccagttggga
1501 catcttctgt gatcaccctg aggctttaat tcactgcttt
ccacactgga cacactgact
1561 tttatccagt tcttttgcct cctcgtaatt tcataaggtt
ctatgaacat acatttacca
1621 atttgcagat cctgcacaaa tatttctgac tggtcctatt
ttctgaaaca ctgttaccat
1681 atgctgtgat gatatggacc tgattccaag ttaaatatac
tctcataaaa ttgaaattac
1741 tattacagga taattcactg tcgcttctct tctgcatttt
cttaataata aattgttttg
1801 gtatacctaa aaaaaaaaaa aaaaaaaaaa aaaaaa