Comparison of ATP and ATP 2'-O-CH3



ATP
ATP-O-CH3

Normal ATP structure (left) is compared to the modified version that added stability to the external guide sequences used to destroy selected mRNAs. The modification added a methyl group in place of the hydrogen normally extending from the 2' carbon of the ribose sugar.


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© Copyright 2001 Department of Biology, Davidson College, Davidson, NC 28036
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