Gene Networks Database

SpF1 - Spec1 interaction

• REGULATOR: SpF1
• TARGET: Spec1
• INTERACTION TYPE: protein-DNA
• INTERACTION RESULT: unknown
• TISSUE: ectoderm
• STAGE: pluteus
• TARGET SITE: CACGTG
• PROOFS: band shift gel assays, DNase I footprinting
• REFERENCES: Tomlinson et al., 1990
• COMMENTS: Changes in the Spec1 gene that remove or modify the SpF1-binding site had no effect on expression when reporter gene fusions containing these mutations were injected into sea urchin eggs and analyzed for expression during embryogenesis.