Gene Networks Database


Lytechinus variegatus Genes in Development: Proto-oncogenes


SU(Lv)-ets-2


Function

SU(Lv)-ets-2 is a member of the ets family of genes. It is the sea urchin gene related to the oncogene v-ets of avian erythroblastosis virus E26.
Southern blot analysis indicated that the SU(Lv)-ets-2 sequences are present in the sea urchin genome only as a single locus (Chen et al., 1988).

Protein

SU(Lv)-ets-2 is the ets-family protein (Chen et al., 1988).
SWISS_PROT: P29773

Subcellular location


Expression Pattern

A single transcript of about 6.8 kb was observed with total RNA from unfertilized eggs and from embryos. Significant levels of SU(Lv)-ets-2 transcript were found from 10 min postfertilization until the blastula stage. After fertilization, expression immediately increases until a maximum level is reached around the 16-cell stage and the morula stage. Thereafter, the level of transcript declines markedly (Chen et al., 1988).

mRNA level

Temporal accumulation

Method 1: Nothern blot analysis
Reference: Chen et al., 1988

Stage
Unfertilized egg
10 min after fertilization
2 cells
4 cells
8 cells
16 cells
32 cells
Morula
Blastula
Gastrula
Pluteus
Level
+ -
+
+
+
+
+ +
+ +
+
+ -
-
-


Sequences

GenBank:

Regulatory Regions


Regulatory Connections

Upstream Genes

SU(Lv)-ets-2

Downstream Genes


Evolutionary Homologues


Links


Bibliography


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