Gene Networks Database
Strongylocentrotus purpuratus Genes in Development:
myb family of transcription factors
SpMyb encodes a transcription factor, which is a member of Myb family.
It is a single copy gene.
SpMyb acts as intramodular negative spatial regulator of the CyIIIa actin gene
(Coffman et al., 1997).
SpMyb is an approximately 77 kDa protein (Boyle et al., 1986).
The SpMyb DNA-binding
three tandem repeats that form the multiple helix-turn-helix
(Aziz et al., 1995; Miglarese et al., 1996).
(Coffman et al., 1997)
SpMyb protein is expressed in blastula-stage embryos.
Whole mount in situ hybridization was employed to vizualize the distribution of SpMyb transcripts
in prism-stage embryos.
At this stage SpMyb transcripts appear to be largely localized to the
oral ectoderm, mesenchyme and endoderm.
SpMyb is therefore present in regions where it is required
to repress CyIIIa transcription (oral ectoderm and mesenchyme),
and in other regions as well (endoderm) (Coffman et al., 1997).
- Gallus gallus A-Myb
- Gallus gallus B-Myb
- Gallus gallus c-Myb
- Drosophila melanogaster Myb
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