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Understanding
the Cell
I am interested in how the cell targets
and utilizes resources, in developing effective methods
to teach the theories and techniques of Cell Biology
and in promoting science literacy. Just as the cell uses
different reactions and interactions to function correctly,
I am involved in collaborative efforts in my research.
Current projects involve collaboration with members of
the Chemistry and Physics Departments
and the Oral Communication Center.
Research
Directions Include:
- Using
optical tweezers to study flagellar regeneration
dynamics . (Biology/Physics) The
flagella of the algae Chlamydomonas
reinhardtii are
dynamic structures used as a model system
to study processes of protein trafficking
(IFT in particular), cytoskeletal dynamics
and force generation. In collaboration
with Dr. J. Yukich (Davidson Physics Department)
we use a laser- based optical trap ('optical
tweezers') to study the pattern of force
generation during flagella regeneration
and to determine the cellular mechanisms
that affect it. (See McCord,
Yukich and Bernd, 2005)
- When
Lungs Breathe: Studying the effects of ozone
on alveolar cells. (Environmental Cell
Biolology). Lung epithelial cells are our first
line of defense against pollutants. We use
a lung cell culture model to explore the relationship
between cell function
and exposure to environmentally relevant levels
of ozone and cell . Projects include testing
effects of ozone levels determined in a local
monitoring project (collaboration with Dr.
Cindy Hauser, Davidson Chemistry Department)
, examining the protective role of surfactant
and the effect of additional cellular stressors
such as increased metabolism (to investigate
exercise induced asthma) or alcohol (to investigate
acute respiratory distress syndrome).
I
have also advised a number of non-laboratory
independent research projects that included topics
in forensics, genetic counseling and bioethics.
You
can see the titles of all
past independent research projects on Dr.
Bernd's C.V. or contact her by email |
