Class Reading Assignments Fall 2008
Bio111: Molecules Genes and Cells,
Prof Bernd


Assigned pages are Study Guide pages and include the reading and study questions that are to be prepared before that day's class.
Readings will be adjusted if needed (written assignment due days and times will not change, only content covered in those assignments).
Check here for updates:

UNIT I

Date Topic Study Guide pgs
Aug 25 :M Introduction to course: What is a Cell? The Inner Life of a Cell
(Lab begins this week. The Lab manual is 'behind' the study guide.)
n/a
W

Unit 1: Stress Response and Sugar release (Cellular Communication)
additional animated resources
Intro to polymers and basic molecule types (carbohydrates, amino acids, lipids)

1-7

F

Sugar release: Second messengers and signaling cascades. New molecule type--nucleic acids

Stopping the cascade: reversing and removing to get back to 'normal'

7-12

Sep 1:M

Using the sugar
Your heart pounds-- Channels, Pumps and Muscle contractions part I

12-20
W Using the sugar
Your heart pounds-- Muscle contractions part II
Myosin heads are dancin' song: http://www.biosongs.com/br3lyrics/6.html
continue/catch up
F

Legs don't fail me now-- synapses, membrane potentials and action potentials

20-25
Sep 8:M

Legs don't fail me now-- from action potentials to chemical signals and back. Synaptic Vesicle release

25- 29
W -- from action potentials to chemical signals and back. Synaptic Vesicle release
 

F

How does an egg know when it is fertilized? Another way of using 2nd messengers Fast and slow blocks--what are they and why do we need them?

Assignment: Complete review 1 from 2007 turn in to Blackboard Dropbox before 11:59pm Monday. Unique Filename= yourinitialsR1.doc (make sure saved as .doc, need to use unique filename so you don't overwrite someone else's work) if Blackboard down-- email file to me
The rules: may (should) work in groups (up to 5 canturn in one copy with all names on it) open book, open notes,
The reason: Your Review is due a week from Monday. Working in groups lets you learn from each other. Doing it now gives you time to improve and decreases cramming/ increases sleep
The payoff: Tuesday 12:30am sample answers will appear on Blackboard so you can compare your responses right away. On Friday we will have a Q and A session and everyone will have prepped

29-35

 

<<- see assignment

Sep 15:M

Fast and slow blocks--what are they and why do we need them?


 

 

W

Other signaling pathways.

35-38

F

Q and A wrap up session.

Review1 will be emailed to you by 1pm today and will cover pages 1-38 of Study Guide and first 4 weeks of Lab. Due before 9:30am Monday the 22nd It can be signed in at my office before 9:20am but must be in my possession by 11:30. See syllabus for details of late policy.

 

UNIT II

Date Topic S G pgs
Sep 22 M Unit II: Genetics    Inherited diseases: Sickle Cell, Cystic Fibrosis, Huntingtons
Mitosis and Meiosis review and compare the stages; Making and interpreting pedigrees,
Meiosis all rapped up http://www.biosongs.com/11.htm
39-42
W

Inherited diseases: How do we talk about them?Traits vs alleles, genotypes vs. phenotypes, learning the terms and how to use them

42-45
F Inherited diseases: DNA and an overview of gene expression (transcription and translation)
Cell cycle rap http://www.biosongs.com/10.htm
45-50
1st set of questions

Sep 29 M

Inherited diseases: The SRY example and the importance of mutations in evolution and the prevalence of silent mutation.
Oral presentations in Lab
Mitosis/meoisis/pedigree quiz available at the end of class. Covers through pg 48

50-54
W

Inherited diseases: Gene expression and revising the common definition of mutation Sickle Cell --the molecular (protein) and genetic (DNA) differences between wildtype and SC hemoglobin. Difference in a gene leading to different protein folding. Mitosis/meoisis due before beginning of class.

54-57
F

Inherited diseases: Intro to Cystic Fibrosis How do you begin searching when there is no 'obvious' protein? ReIntroduction to Mendels Laws

58-62
Oct 6 Inherited diseases: Cystic Fibrosis: How to we find a gene in all that DNA:
'Classic' Linkage analysis / RFLPs and VNTRs

62-67
W Inherited diseases: Cystic Fibrosis -- A chromosome is 'big'. How do we get closer: recombination
67-74

F

Inherited diseases: Cystic Fibrosis-- Positional Cloning and Genomic approaches

Do, and check, questions found at this link
http://www.bio.davidson.edu/Courses/Bio111/campbell/CF_RFLP/RFLP_CF.html
74-77
Oct 13 : Fall Break  

W

Inherited diseases: Cystic Fibrosis-- What is the CF mutation? 77-80
F Inherited diseases: Cystic Fibrosis-- What is the problem and how can we tell? 80-83

Oct 20 M

-- What is the problem and how can we tell?  
W Class: Wrap up and Q&A. (optional)
Come with questions Review 2 will be emailed to you by 8:30am today and will cover pages SG 39-83 and LM55-75

 
F Review 2 DUE in my possession Before 10am on Friday
 

UNIT III

Date Topic Study Guide pgs
Oct 27 Unit III: Bioenergetics: Poison Pot and an Introduction to energy 89-92
W Poison Pot: Light, Pigments and Energy
How and where do molecules store energy?
Listen to the kinetic and potential energy song http://www.acme.com/jef/science_songs/kinetic_potential-32.mp3
92-98
F Poison Pot: The Light Reactions and harvesting energy from photons
98-99
Nov 3 Poison Pot: Calvin-Benson Cycle and making food
99-103

W

Cyanide and poison grapes: Only plants photosynthesize-- all cells metabolize glucose, how does that work? Cellular respiration (glycolysis/ Citric Acid Cycle and Oxidative Phosphorylation)
103-107
F Catch up/ pull together
Written and oral presentations in Lab

no new reading

Nov 10 Cyanide and poison grapes: Citric Acid Cycle and Oxidative Phosphorylation
webquiz available
through Blackboard

107-109
W Cyanide and poison grapes: Citric Acid Cycle and Oxidative Phosphorylation
Amino Acid/ Peptide webquiz due by 5pm Friday April 11th

109-112

F

Why health officials require vaccinations during floods and Carbon is not enough-- need nitrogen, but how? 112-116
Nov 17 Wrap up and Question/Answer session .
Review 3 will be emailed to you by 1pm today and will cover pages SG 88-116 and LM76-84
 
W Review 3 DUE At my OFFICE Before 5pm on Friday  

UNIT IV

Date Topic Study Guide pgs
F Unit IV: Other Interesting Topics:Epidemiology, Communicable diseases including HIV  (note we are skipping a topic) 132-136

Nov 24

HIV/AIDs: retroviruses
136-140

W&F

Thanksgiving break LAB Written Assignments due Tuesday
Final exam prep question available today

 

Dec 1

HIV/AIDs: attempts at treatment

140-148
W
HIV/AIDs: methods of detection/ diagnosis

148-152

F Wrap up
Final Exam will be emailed to you by Monday am
 


Final Exam Due Monday Dec 15th before Noon (Turn in at my office)