Reading2011

Bio111: Molecules Genes and Cells, Prof Bernd
Reading Assignments Spring 2011
Assigned pages are Study Guide pages and include the reading and study questions that are to be prepared before that day's class.
Readings will be adjusted if needed (written assignment due days and times will not change, only content covered in those assignments).

UNIT I

Date	Topic	Study Guide pgs
Jan 10: M	Introduction to course: What is a Cell? The Inner Life of a Cell (Lab begins this week. The Lab manual is 'behind' the study guide.)	n/a
W	Unit 1: Stress Response and Sugar release (Cellular Communication) additional animated resources Intro to polymers and basic molecule types (carbohydrates, amino acids, lipids)	1-7
F	Sugar release: Second messengers and signaling cascades. New molecule type--nucleic acids Stopping the cascade: reversing and removing to get back to 'normal'	7-12
Jan17:M	No class: Participate in King Day activities
W	Using the sugar Your heart pounds-- Channels, Pumps and Muscle contractions part I	12-20
F	Using the sugar Your heart pounds-- Muscle contractions part II Myosin heads are dancin' song: http://www.biosongs.com/br3lyrics/6.html	continue
Jan 24:M	Legs don't fail me now-- synapses, membrane potentials and action potentials	20-25
W	Legs don't fail me now-- from action potentials to chemical signals and back. Synaptic Vesicle release	25- 29
F	-- from action potentials to chemical signals and back. Synaptic Vesicle release	continue
Jan31: M	How does an egg know when it is fertilized? Another way of using 2nd messengers Fast and slow blocks--what are they and why do we need them?	29-35
W	Fast and slow blocks--what are they and why do we need them?	continue
F	Other signaling pathways. Review1 will be emailed to you by 1pm today and will cover pages 1-38 of Study Guide and first 4 weeks of Lab. It is DUE in my office by 9:20 Monday. See syllabus for details of late policy.	35-38

UNIT II

Date	Topic	S G pgs
Feb 7 M	Review 1 Due before 9:20am. Graphical analysis: prepping for your lab article. See Lab manual exercises Unit II Genetics Inherited diseases: Sickle Cell, Cystic Fibrosis, Huntingtons, Introduced	39-42
W	Unit II Genetics Inherited diseases: Sickle Cell, Cystic Fibrosis Huntingtons, Mitosis and Meiosis Review making and interpreting pedigrees, Meiosis all rapped up http://www.biosongs.com/11.htm	continued
F	No class (out of town on NSF panel)
Feb 14 M	Inherited diseases: How do we talk about them?Traits vs alleles, genotypes vs. phenotypes, learning the terms and how to use them	42-45
W	Inherited diseases: DNA and an overview of gene expression (transcription and translation) Cell cycle rap http://www.biosongs.com/10.htm	45-50 1st set of questions
F	Inherited diseases: The SRY example and the importance of mutations in evolution and the prevalence of silent mutation. Inherited diseases: Gene expression and revising the common definition of mutation Sickle Cell-- differences in gene leading to differences in protein folding Mitosis/meoisis/pedigree quiz available at the end of class (On Blackboard). Covers through pg 48	50-54
Feb 21 M	Inherited diseases: Gene expression and revising the common definition of mutation Sickle Cell-- differences in gene leading to differences in protein folding	54-58
W	Inherited Diseases: Intro to Cystic Fibrosis How do you begin searching when there is no 'obvious' protein? ReIntroduction to Mendel's Laws	58-62
F	Inherited diseases: Cystic Fibrosis: How to we find a gene in all that DNA: 'Classic' Linkage analysis / RFLPs and VNTRs Mitosis/meoisis quiz due before 9:20am	62-67
Feb 28	Spring Break
Mar 7M	Inherited diseases: Cystic Fibrosis continues
W	Inherited diseases: Cystic Fibrosis -- A chromosome is 'big'. How do we get closer: recombination	67-74
F	Inherited diseases: Cystic Fibrosis-- Positional Cloning and Genomic approaches Do, and check, questions found at this link http://bio.davidson.edu/Courses/Bio111/campbell/CF_RFLP/RFLP_CF.html	74-77
Mar 14M	Inherited diseases: Cystic Fibrosis-- What is the CF mutation?	77-80
W	Inherited diseases: Cystic Fibrosis-- What is the problem and how can we tell?Review 2 will be emailed to you today, covers pages SG 39-83 and LM55-75	80-83
F	Class: Wrap up and Q&A. (optional) Come with questions

UNIT III

Date	Topic	Study Guide pgs
Mar 21 M	Review 2 DUE Before 9:20 Unit III: Bioenergetics: Poison Pot and an Introduction to energy	89-93
W	Poison Pot: Light, Pigments and Energy How and where do molecules store energy? Listen to the kinetic and potential energy song http://www.acme.com/jef/science_songs/kinetic_potential-32.mp3	93-98
F	Poison Pot: The Light Reactions and harvesting energy from photons	98-99
Mar 28M	Poison Pot: Calvin-Benson Cycle and making food Lab	99-103
W	Cyanide and poison grapes: Only plants photosynthesize-- all cells metabolize glucose, how does that work? Cellular respiration (glycolysis/ Citric Acid Cycle and Oxidative Phosphorylation) webquiz available through Blackboard	103-107
F	Pull together	continue
Apr 4 M	Cyanide and poison grapes: Citric Acid Cycle and Oxidative Phosphorylation	107-112
W	Cyanide and poison grapes: Citric Acid Cycle and Oxidative Phosphorylation	continue
F	Why health officials require vaccinations during floods and	112-115
Apr 11M	Carbon is not enough-- need nitrogen, but how? Amino Acid/ Peptide webquiz due by 5pm Friday	115-117
W	Carbon is not enough-- need nitrogen, but how?	continue
F	Wrap up and Question/Answer session . Review 3 emailed to you today covers pages SG 88-117 and LM76-84 DUE before 9:20am on Monday April 18
Apr 18 M	Unit IV: Other Interesting Topics:Epidemiology, Communicable diseases including HIV (note we are skipping a topic)	131-136

UNIT IV

Date	Topic	Study Guide pgs
F	A brief recap of human anatomy
April 18 M	Review 3 due before 9:20am HIV/AIDs: retroviruses Final exam pre-questions emailed to you today.	136-140
W	Bring lab article drafts: group-work time
F	HIV/AIDs: Treatment approaches Final Exam will be emailed to you by Wed am	140-147
Apr 25 M	Easter Break
W	HIV/AIDs: methods of detection/ diagnosis Wrap up	147-151
F	Available in office for questions
	Final Exam Due Friday May 6th before Noon (Turn in at my office)