Reading2013

Bio111: Molecules Genes and Cells, Prof Bernd
Reading Assignments Spring 2013
Assigned pages are Study Guide pages and include readings from other sources and study questions that are to be prepared before that day's class.
Readings will be adjusted if needed (written assignment due days and times will not change, only content covered in those assignments).

UNIT I

Date	Topic	Study Guide pgs
Jan 14: M	Introduction to course: What is a Cell? The Inner Life of a Cell There IS lab this week	n/a
W	Unit 1: Stress Response and Sugar release (Cellular Communication) Intro to polymers and basic molecule types (carbohydrates, amino acids, lipids)	1-7
F	Sugar release: Second messengers and signaling cascades. New molecule type--nucleic acids Stopping the cascade: reversing and removing to get back to 'normal'	7-12
Jan 21: M	No Class Monday Martin Luther King Jr Day: Participate in King Day activities (NO lab this week)
W	Using the sugar Your heart pounds-- Channels, Pumps and Muscle contractions part I	12-20
F	No Class (I will be in D.C.)
Jan 28: M	Using the sugar Your heart pounds-- Muscle contractions part II Myosin heads are dancin' song: http://www.biosongs.com/br3lyrics/6.html	continue
W	Legs don't fail me now-- synapses, membrane potentials and action potentials	20-25
F	Legs don't fail me now-- from action potentials to chemical signals and back. Synaptic Vesicle release	25- 29
Feb 4: M	-- from action potentials to chemical signals and back. Synaptic Vesicle release	continue
W	How does an egg know when it is fertilized? Another way of using 2nd messengers Fast and slow blocks--what are they and why do we need them?	29-35
F	No Class Meeting Friday (I will be in Princeton) : Review1 will be emailed to you by 1pm Thursday and will cover pages 1-35 of Study Guide and first 4 weeks of Lab. It is DUE in my office by 9:20 Monday. See syllabus for details of late policy.

UNIT II

Date	Topic	S G pgs
Feb 11: M	Review 1 Due before 9:20am. Unit II Genetics Inherited diseases: Sickle Cell, Cystic Fibrosis, Huntingtons, Introduced	39-42
W	Unit II Genetics Inherited diseases: Sickle Cell, Cystic Fibrosis Huntingtons, Mitosis and Meiosis Review making and interpreting pedigrees, Meiosis all rapped up http://www.biosongs.com/11.htm	continued
F	Inherited diseases: How do we talk about them?Traits vs alleles, genotypes vs. phenotypes, learning the terms and how to use them	42-45
Feb 18 M	Inherited diseases: DNA and an overview of gene expression (transcription and translation) Cell cycle rap http://www.biosongs.com/10.htm	45-50 1st set of questions
W	Inherited diseases: The SRY example and the importance of mutations in evolution and the prevalence of silent mutation. Inherited diseases: Gene expression and revising the common definition of mutation Sickle Cell-- differences in gene leading to differences in protein folding Mitosis/meoisis/pedigree quiz available at the end of class (On Blackboard). Covers through pg 48	50-54
F	Inherited diseases: Gene expression and revising the common definition of mutation Sickle Cell-- differences in gene leading to differences in protein folding	54-58
Feb 25 M	Inherited Diseases: Intro to Cystic Fibrosis How do you begin searching when there is no 'obvious' protein? ReIntroduction to Mendel's Laws	58-62
W	Inherited diseases: Cystic Fibrosis: How to we find a gene in all that DNA: 'Classic' Linkage analysis / RFLPs and VNTRs Mitosis/meoisis/pedigree quiz DUE before 11:59pm Wednesday night	62-67
F	Inherited diseases: Cystic fibrosis Continued
Mar 4	Spring Break
Mar 11 M	Inherited diseases: Cystic Fibrosis -- A chromosome is 'big'. How do we get closer: recombination	67-74
W	Inherited diseases: Cystic Fibrosis-- Positional Cloning and Genomic approaches Do, and check, questions found at this link http://www.bio.davidson.edu/Courses/Bio111/campbell/CF_RFLP/RFLP_CF.html	74-77
F	Positional Cloning and Genomic approaches continued	continue
Mar 18 M	Inherited diseases: Cystic Fibrosis-- What is the CF mutation?	77-80
W	Inherited diseases: Cystic Fibrosis-- What is the problem and how can we tell?covers pages SG 39-83 and LM55-75	80-83
F	No Class Meeting Friday : Review2 will be emailed to you by 1pm Thursday and will cover pages SG 39-83 and LM55-PCR. It is DUE in my office by 9:20 Monday. See syllabus for details of late policy.

UNIT III

Date	Topic	Study Guide pgs
Mar 25 M	Review 2 DUE Before 9:20 Unit III: Bioenergetics: Poison Pot and an Introduction to energy (note: starting new unit material but 2nd review still not due until Monday 3/25 to give you fexibiity)	89-93
W	Poison Pot: Light, Pigments and Energy How and where do molecules store energy? Listen to the kinetic and potential energy song http://www.acme.com/jef/science_songs/kinetic_potential-32.mp3	93-98
F	Poison Pot: The Light Reactions and harvesting energy from photons	98-99
Apr 1: M	Easter Break
W	Poison Pot: Calvin-Benson Cycle and making food	99-103
F	Cyanide and poison grapes: Only plants photosynthesize-- all cells metabolize glucose, how does that work? Cellular respiration (glycolysis/ Citric Acid Cycle and Oxidative Phosphorylation) webquiz available through Blackboard	103-107
Apr 8: M	Pull together	continue
W	Cyanide and poison grapes: Citric Acid Cycle and Oxidative Phosphorylation	107-112
F	Cyanide and poison grapes: Citric Acid Cycle and Oxidative PhosphorylationAmino Acid/ Peptide webquiz due by 5pm Friday	continue
Apr 15: M	Why health officials require vaccinations during floods	112-115
W	Carbon is not enough-- need nitrogen, but how?	115-117
F	Carbon is not enough Review 3 emailed to you by 1pm today covers pages SG 88-117 and Flagella regeneration lab It is DUE in my office by 9:20 Wednesday. See syllabus for details of late policy.	continue
Apr 22 M	No class meeting Monday (you have a review to take) Yes there is lab Final exam 'pre-questions' emailed to you today.

UNIT IV

Date	Topic	Study Guide pgs
Apr 24 W	Review 3 due before 9:20am Unit IV: Other Interesting Topics:Epidemiology, Communicable diseases including HIV (note we are skipping a topic) A brief recap of human anatomy	no reading
F	HIV/AIDs history and info	131-136
Apr 29 M	Viruses and retroviruses	136-140
W	HIV/AIDs: Treatment approaches	140-147
F	HIV/AIDs: methods of detection/ diagnosis Wrap up Final Exam will be emailed to you	147-151
	Available in office for questions
	Final Exam Due Monday May 13th before Noon (TURN IN TO MY OFFICE No exam envelope, no exam center--> 'take home' like other reviews