Reading2013

Bio111: Molecules Genes and Cells, Prof Bernd
Reading Assignments FALL 2013
Assigned pages are Study Guide pages and include readings from other sources and study questions that are to be prepared before that day's class.
Readings will be adjusted if needed (written assignment due days and times will not change, only content covered in those assignments).

UNIT I

Date:	Topic	Study Guide pgs
Aug 27: T	There IS lab this week Before class: complete 'for before the first day of class' on Moodle. Introduction to course: What is a Cell? The Inner Life of a CellUnit 1: Stress Response and Sugar release (Cellular Communication) Intro to polymers and basic molecule types (carbohydrates, amino acids, lipids)	1-3
R	Sugar release: Second messengers and signaling cascades. New molecule type--nucleic acids Stopping the cascade: reversing and removing to get back to 'normal'	4-12
Sept 3: T	Using the sugar Your heart pounds-- Channels, Pumps and Muscle contractions part I	12-18
R	Using the sugar Your heart pounds-- Muscle contractions part II Myosin heads are dancin' song: http://www.biosongs.com/br3lyrics/6.html	18-20
Sept 10: T	Legs don't fail me now-- synapses, membrane potentials and action potentials	20-25
R	Legs don't fail me now-- from action potentials to chemical signals and back. Synaptic Vesicle release	25-29
Sept 16: T	How does an egg know when it is fertilized? Another way of using 2nd messengers Fast and slow blocks--what are they and why do we need them?	29-35
R	No Class Meeting Thursday: Review1 will be emailed to you by 1pm Wednesday and will cover pages 1-35 of Study Guide and first 4 weeks of Lab. It is DUE in my office before NOON MONDAY. See syllabus for details of late policy.

UNIT II

Date	Topic	S G pgs
Sept 24: T	Review 1 was Due before Noon Monday Unit II Genetics Inherited diseases: Sickle Cell, Cystic Fibrosis, Huntingtons, Introduced Mitosis and Meiosis Review making and interpreting pedigrees, Meiosis all rapped up http://www.biosongs.com/11.htm	39-42
R	Inherited diseases: How do we talk about them?Traits vs alleles, genotypes vs. phenotypes, learning the terms and how to use them	42-45
Oct 1: T	Inherited diseases: DNA and an overview of gene expression (transcription and translation) Cell cycle rap http://www.biosongs.com/10.htm	45-51
R	Inherited diseases: The SRY example and the importance of mutations in evolution and the prevalence of silent mutation. Inherited diseases: Gene expression and revising the common definition of mutation/ Sickle Cell-- differences in gene leading to differences in protein folding	51-57
Oct 8: T	Inherited Diseases: Intro to Cystic Fibrosis How do you begin searching when there is no 'obvious' protein? ReIntroduction to Mendel's Laws Mitosis/meoisis/pedigree quiz available at the end of class (On Moodle). Covers through pg 48	58-62
R	Inherited diseases: Cystic Fibrosis: How to we find a gene in all that DNA: 'Classic' Linkage analysis / RFLPs and VNTRs Mitosis/meoisis/pedigree quiz DUE before 11:59pm Friday night	62-68
Oct 15: T	Fall breakNo Class or lab today
R	Inherited diseases: Cystic Fibrosis -- A chromosome is 'big'. How do we get closer: recombination Inherited diseases: Cystic Fibrosis-- Positional Cloning and Genomic approaches Do, and check, questions found at this link http://bio.davidson.edu/Courses/Bio111/campbell/CF_RFLP/RFLP_CF.html AND work through the genomic exercise on pg 75	67-76
Oct 22: T	Inherited diseases: Cystic Fibrosis-- What is the CF mutation?	77-80
R	Inherited diseases: Cystic Fibrosis-- What is the problem and how can we tell? Review2 will be emailed to you by 1pm Thursday and will cover pages SG 39-83 and LM55-PCR. It is DUE in my office by Noon Monday. See syllabus for details of late policy	80-83
Oct 29: T	No Class Meeting Tuesday : (there is lab)

UNIT III

Date	Topic	Study Guide pgs
Oct 31: R	Unit III: Bioenergetics: Poison Pot and Light, Pigments and Energy How and where do molecules store energy? Listen to the kinetic and potential energy song http://www.acme.com/jef/science_songs/kinetic_potential-32.mp3	89-97
Nov 5: T	Poison Pot: The Light Reactions and harvesting energy from photons & Calvin-Benson Cycle and making food Amino Acid/Peptide Webquiz available through Moodle	98-103
R	Cyanide and poison grapes: Only plants photosynthesize-- all cells metabolize glucose, how does that work? Cellular respiration (glycolysis/ Citric Acid Cycle and Oxidative Phosphorylation) Amino Acid/ Peptide webquiz due by 5pm FRIDAY	103-110
Nov 12: T	Cyanide and poison grapes: Citric Acid Cycle and Oxidative Phosphorylation Why health officials require vaccinations during floods	110-114
R	Carbon is not enough-- need nitrogen, but how? Review 3 emailed to you by noon Wednesday today covers pages SG 88-117 and Flagella regeneration lab It is DUE in my office by Noon Monday. See syllabus for details of late policy.	115-117
Nov 19: T	No class meeting (there IS lab)

UNIT IV

Date	Topic	Study Guide pgs
Nov 21: R	Unit IV: Other Interesting Topics:Epidemiology, Communicable diseases including HIV (note we are skipping a topic) A brief recap of human anatomy *Final exam 'prep questions' emailed to you today.*	no reading
Nov 26: T	HIV/AIDs history and info & Viruses and retroviruses	131-138
R	Thanksgiving break: No class
Dec 3: T	HIV/AIDs: Treatment approaches	39-147
R	HIV/AIDs: methods of detection/ diagnosis Wrap up Final Exam will be emailed to you	147-151
	Available in office for questions
	Final Exam Due Monday DEC 17th before Noon TURN IN TO MY OFFICE No exam envelope, no exam center--> 'take home' like other reviews