Karen K. Bernd

Academic Background

2004- present: Associate Professor, Biology Department, Davidson College
1998-2004: Assistant Professor, Biology Department, Davidson College
1996-1998: Research Associate/NIH Postdoctoral Fellow, Developmental, Cell and Molecular Biology Group,  Duke University Bruce Kohorn, advisor

1992; 1996: M.A., and Ph.D. Molecular Biology,  Princeton University, Elizabeth Sztul advisor
1990: B.A., Biology, Franklin and Marshall College
, Carl Pike advisor

Courses
Bio111: Molecules, Genes and Cells (yearly)
Bio308: Cell Biology (yearly)
Bio361: Vesicular Traffic, Dogma or Myth (S '99)
Bio361/362: From Venoms and Toxins to Drugs (S'00 and F'00, '01)
Bio361/362: Genetically Modified Organisms (02, 03, 04)
Bio361: Forensic Serology ('05, 06)
Bio371/372: Independent Research (also see below)
CIS341: Introduction to Forensic Sciences (S '04, '05, '06)
Bio351: Epithelial Cell Biology (group investigation)(F'07)

Selected Publications and Presentations
Research Papers *denotes undergraduates as co-authors
Guilford, W.H., L.E. Aust*, and K.K. Bernd (2006) “Whole-cell flagellum-based motility studied using back focal plane interferometry in a laser trap transducer” Conference Record of the Fortieth Asilomar Conference on Signals, Systems and Computers: 178-82.

McCord, R.P.*, Yukich. J. N.. and Bernd, K.K.. 2005. Analysis of Force Generation during Flagellar Assembly Through Optical Trapping of Free-swimming Chlamydomonas reinhardtii. Cell Motility and the Cytoskeleton 61: 137-144

Bernd, K. K., and Cook, N.*. 2002. Microscale assay monitors algal growth characteristics. Biotechniques 32: 1256-1259. http://www.biotechniques.com/ (subscription free but must register or password then search)

Timm, S., Titus, B., Bernd K., and Barroso, M. (1999) The EF-hand Ca2+-binding Protein p22 Associates with microtubules in an N-myristoylation dependent manner. Molec Bio of the Cell 10: 3473-3488. http://www.molbiolcell.org/cgi/content/full/10/10/3473

Bernd, K.K., and Kohorn, B.D. (1998) Tip loci: Six Chlamydomonas nuclear suppressors that permit the translocation of proteins with mutant thylakoid signal sequences. Genetics 149:1293-1301. http://www.genetics.org/content/vol149/issue3/

Books and Book Chapters
Bernd K.K. 2004 'Biology' In Condense Knowledge Eds W. Pearson, L. Hunt and M. Hattikudur. Harper Collins. http://www.condensedknowledge.com

Bernd, K.K.' User's Guide'. (2002) Supplemental material for instuctors included with Alberts et al. Molecular Biology of the Cell 4th edition. Available in pdf format at http://www.garlandscience.com/MBoC4/supplements.html

Bernd, K.K., Perret, M.C., and Kohorn, B.D. (1998) Chloroplast protein translocation in Chlamydomonas. In Molecular Biology of Chloroplasts and Mitochondria in Chlamydomonas. Eds. J. –D. Rochaix,, M. Goldschmidt-Clermont, and S. Merchant

Books Reviews and Other Articles
TP Msg. 623 “Merging Teaching and Research” a response to ‘Sufficient Time for Research’ Initially posted 2/14/05, ‘Tomorrow's Professor’ faculty development resource sponsored by the Stanford University Center for Teaching and Learning. Posting written at the request of the moderator  Rick Reis. Archived at http://ctl.stanford.edu/Tomprof/index.shtml

Bernd, K.K. and V. Statler* (2004) Customer Focus: Undergraduates Study Gene Expression in S.cerevisiae Using a Student-Optimized Protocol. Epicentre Forum 11; 4

Bernd, K. (2003) Waiting for 4.1: Review of Roche Genetics Education Program CD-rom version4.0. Cell Biology Education 2: 152-155. http://www.cellbioed.org/articles/vol2no3/article.cfm?articleID=66

Bernd K.K. (2002) Book Review: Mood Genes: Hunting for the Origins of Mania and Depression. Journal of Undergraduate Neuroscience. 1(1); R1-R2. http://www.funjournal.org/downloads/R1bernd.pdf

Abstracts
*Clodfelter, C.,  *Shaban, M., Yukich, J.,  Bernd, K.K. (submitted) Analysis of Force Generation Patterns During C. reinhardtii Flagella Regeneration. America Society for Cell Biology Annual Meeting, Washington, D.C. Dec 2007

Bernd, K.K.,  DeForest Hauser, C., *Nam, A., *Raver, C., *Weaver, A. (submitted)  An epithelial Type II Cell System to Investigate Links between Environmental Factors and Lung Injury. America Society for Cell Biology Annual Meeting, Washington, D.C. Dec 2007

Yukich, J. *Shaban, M., * Clodfelter, C., Bernd. KK 2007. Measurement of swimming force generation during flagella regeneration in Chlamydomonas reinhardtii. SES Meeting of the American Physical Society.  Nashville, TN. Nov 2007

Yukich, J. *Shaban, M., * Clodfelter, C., Bernd. KK 2007. Measurement of swimming force generation in Chlamydomonas reinhardtii using optical tweezers. Optics in the Southeast Annual Meeting. Clemson University Oct 2007

Guilford W., *Aust,L, Bernd, K.K., (2006) Whole-cell flagellum-based motility studied using back focal plane interferometry in a laser trap transducer. 40th Asilomar Conference on Signals, Systems and Computers. Pacific Grove, California Platform talk. Nov 2006

Shaban, M.*, Bernd, K, and Yukich, J., (2006) Improving Optical Trap Calibration Techniques for Chlamydomonas Cells. NCS-AAPT meeting Elon College. Sept 2006. Mona Shaban presented platform talk.

Yukich, J., Bernd, K.K., and R.P.McCord*. 2005. Biophysical analysis of swimming force by Chlamydomonas flagella. Annual Meeting of the SE section of the American Physical Society. Platform talk.

Newton, K.*, Pickens, A.*, and K.K.Bernd. 2005. Novel organic compounds DRR 3 and DRR 5 affect growth rate differentially in model bacteria Escherichia coli, Salmonella typhimurium, and Staphylococcus simulans. North Carolina Academy of Science Annual Meeting. Meredith College, Raleigh, NC.

McCord, R.P.*, Yukich. J. N., and K.K. Bernd. 2004 Optical Trap Analysis Reveals  Exhibit Complex Patterns of  Swimming Force Increase During Flagella Elongation Chlamydomonas reinhardtii. American Society for Cell Biology annual meeting, Washington, DC.

Bernd, K. K. 2004. Undergraduates Ranking Grant Proposals and Writing a Curriculum Vitae Why and How? American Society for Cell Biology annual meeting, Washington, DC.

McCord, R.P.*, K.K. Bernd and J.N. Yukich. (2004) Using Optical Tweezers to Measure the Force Exerted by Original and Regenerated Flagella of Chlamydomonas reinhardtii. NC Academy of Science Annual meeting, Catawba College, Salsibury, NC. Awarded First place in Oral Presentation Division.

Wilson, A.R.*, J. Neill, E. Stevens, and K.K. Bernd. (2004) Analysis of Purine Derivatives for Antimicrobial Activity. NC Academy of Science Annual meeting, Catawba College, Salisbury, NC. Awarded First place in Undergraduate Poster Division..

Borak, B.*, M. D. Schuh, and K. K. Bernd. 2004. Kinetics of horseradish peroxidase catalyzed reaction of p-cresol in aqueous solution containing trifluoroethanol. NC Academy of Science Annual meeting, Catawba College, Presented March 2004.

McCord, R.P.*, Bernd, K.K., and J.N. Yukich (2004) Optical Tweezers and Biological Forces: Using a laser Trap to Measure the Swimming Force Exerted by the Flagella of Chlamydomonas reinhardtii. Biophysical Society Annual Meeting. Baltimore, MD to be presented February, 2004.

McCord, R.P.*, Bernd, K.K., and J.N. Yukich (2003) The Design and Construction of an Optical Tweezers Laser Apparatus to Measure Piconewton Scale Biological Forces. Annual Meeting of the SE section of the American Physical Society. Wilmington, NC. Awarded Second place in Undergraduate Poster Division.

Neill, J.*, Wilson, A.*, Bernd, K.K. and E. Stevens (2003) Synthesis and Biological Activity of 1,2,3-triazoles. American Chemical Society annual meeting. Atlanta, GA, November 2003.

Newton, K.*, Chase, M.*, Toran, P.*, and K.K. Bernd (2003) Characterizing golgin targeting requirements. Poster at North Carolina Academy of Science Meeting, at UNC-Wilmington, Wilmington, NC. Awarded Third Place John Derieux Award for Outstanding Undergradaute Research; Student Poster division.

Statler, V.* and K.K. Bernd (2003) Optimizing Comparative RT-PCR for undergraduate Cell Biology laboratories. Presentation at North Carolina Academy of Science Meeting, at UNC-Wilmington, Wilmington, NC. Awarded Second Place John Derieux Award for Outstanding Undergradaute Research; Science Education division. Presentated by Victoria Statler ('03)

Bernd, K. K. and Cook, N.* 2001. Protein translocation mutants demonstrate altered herbicide resistance in novel microscale assay. Poster at American Society for Cell Biology annual meeting,  Washington, DC.

Larned, C.*, Nugent, E*, McKillop, J. C.*, Bernd, K.K. and D. Wessner. Use of Rapid, Chemiluminescent DNA Sequencing and Phenol-free RNA Isolation Protocols in the Undergraduate Curriculum. ASM Annual Meeting abstract/poster, Orlando, FL

McKillop, J. C. * and K. K. Bernd (2001) Optimizing S. cerevisiae differential gene expression protocols for use in undergraduate laboratories. NC Academy of Science meeting, presentation by J. McKillop (class of '01).

Bernd, K K (2000) Linking the WWWeb and Seminar Courses: Lessons learned from Vesicular Traffic: Dogma or Myth. Invited Speaker American Society for Cell Biology Annual Meeting.

K K Bernd, *C Larned,, *J McKillop, *E Nugent, *S Riedley, and D Wessner (2000). DNA Sequencing and Differential Expression Studies: Non-radioactive, Non-toxic and Accessible. American Society for Cell Biology Annual Meeting. MCB Supplement

Web-based resources
Please also see homepage resources at http://www.bio.davidson.edu/people/kabernd/BerndCV/BerndCV.html

http://biology.ecsu.ctstateu.edu/chlamyteach/microscale.htm “Growing Chlamydomonas in microscale liquid cultures” Guide to help use Chlamydomonas as a teaching tool. Part of Research 2000 Coordinated and Web-mastered by Michael Adams, Eastern Connecticut State University

Presentations
‘Making Labs Engaging’ Guest speaker in Graduate course entitled: Bio390: Seminar in Teaching College Biology. Duke University, Durham, NC. March 4, 2006.

'The Broad Spectrum of Academia: How academic cultures vary across institutions' Panelist with Albert Young, Assistant Professor, Physics, North Carolina State University; and Jeff Rathmell, Assistant Professor, Pharmacology and Cancer Biology, Duke University Medical Center. January 2005. Duke University Postdoctoral Association organized event. Duke University, Durham, NC.

'Integrating Research, Teaching, and Learning' Guest speaker in Graduate course entitled: Seminar in Teaching Biology March 2004. Duke University, Durham, NC.

'Protein Translocation and Herbicide Resistance: How the Summer Sun Causes the Birth of an Assay' Invited speaker Biology Evening Seminar Series March 2003 Franklin and Marshall College, Lancaster, PA

Guest lecturer in Bio334: Biochemistry and Molecular Biology: Metabolism and Information Pathways.March 2003 Franklin and Marshall College, Lancaster, PA

'Information Fluency' Invited PFF program speaker (Preparing Future Faculty) March 2002 Duke University, Durham, NC.

'Integrating Webauthoring into Seminar Courses' Invited PFF program speaker (Preparing Future Faculty) March 2001 Guilford College, Greensboro, NC.

'Linking the WWWeb and Seminar Courses: Lessons learned from Vesicular Traffic: Dogma or Myth'. Invited Speaker American Society for Cell Biology Annual Meeting. (12/2000)


Selected Funding and Awards (five years)

Interdisciplinary Summer Internship Program in Biochemistry (funded by Merck -AAAS) Karen Bernd and Cindy Hauser co-PIs. 3 year grant to support collaborative research in the Chemistry and Biology departments.Each intern is involved in research in biochemistry fields and has advisors in both departments. Grant supports 1) stipend for 4 students per summer; 2) travel and supply money for each student; 3) summer lunch lab group lunches 4) student fieldtrip (per summer) to explore industry 5) fall lecture series inviting Biochemical researchers. $60,000 2007-2009

“Characterization of Functional Flagella with Optical Tweezers’ HHMI Summer Research Program. Student Fellow support. Co-Advisor Karen Bernd and John Yukich  $5700. Summer 2007                                    

Establishing models to study the effects of ozone on surfactant and lung epithelial cells’ Faculty Study and Research Grants Davidson College, Davidson, NC: $3,200 Summer 2007 

“Forensic Serology Seminar: Communicating Scientific Information to Audiences with Different Scientific Backgrounds” Faculty Study and Research: Teaching Improvement Grant, Davidson College, Davidson, NC: $2,600 Summer 2005

"REU Site: Developing Student Scientists: Collaborative Research in the Life Sciences at Davidson College." NSF-REU Site Grant : Co-PI: Michael E. Dorcas, Mark T. Stanback, Karen K. Bernd, $248,101 2002-2006

Interdisciplinary Summer Internship Program in Biochemistry (funded by Merck -AAAS) Karen Bernd and Erland Stevens co-PIs. 3 year grant to support collaborative research in the Chemistry and Biology departments.Each intern is involved in research in biochemistry fields and has advisors in both departments. Grant supports 1) stipend for 4 students per summer; 2) travel and supply money for each student; 3) summer lunch lab group lunches 4) student fieldtrip (per summer) to explore industry 5) fall lecture series inviting Biochemical researchers. $60,000 Summer 2003-2006

"Optimizing Comparative RT-PCR for Cell Biology" Faculty Study and Research Grant Davidson College $2400 Summer 2003

"Building Optical Tweezers" Faculty Study and Research Grant Davidson College $600 Summer 2003

“Providing Connections: Resources for Cell Biology” Mellon Technology Fellow, Associated Colleges of the South $2500 Summer 2002

“Microscale screening: Testing the general applicability of a novel technique” Faculty Study and Research Grant Davidson College, $2750 Summer 2002 Student researcher: Casssandra Sams ('03)

“Characterizing the resistance of Chlamydomonas reinhardtii tip mutants to the herbicide Valor” Faculty Study and Research Grant
Davidson College, $3000 Summer 2001 Student researcher Brian Strife ('02)

“Maximizing Audience and Student-Perceived Relevance: Teaching Information Fluency in Introductory Biology Courses” Information Fluency Grant, Associated Colleges of the South co-Investigators M. Muchane (Center for Instructional Technology), F. Molinek (Library) and V. Statler ('03) $3655 May 2001-April 2002
 

 

Undergraduate Student Research Projects Mentored
pictures

Kelly Carter '00 'Using fluorescence microscopy to study cell signaling: optimizing fus1 and control marker fluorescence in S. cerevisiae'
Tyler Richmond '99 'How little is too little? Determining the levels of fluorescence nucleotides required for Fluor S detection'

Evans Thompson '99 'Seeing' signaling at the transcript level: optimizing RNA isolation and detection methods for undergraduate laboratory use'

Before 1999
Edward Kim: senior thesis 'Cloning of wild type tip1 locus and chloroplastic SRP54 from
Chlamydomonas reinhardtii(Spring 1997-Spring 1998, Duke University)

Elizabeth Wagner: senior thesis 'Are trafficking signals conserved? Expression of mammalian pIgA-R  in  S. cerevisiae (Fall 1995-Spring 1996, Princeton University)

Professional Organizations:

National  
American Association for the Advancement of Science (AAAS)  
American Society for Cell Biology (ASCB):
N.C. Congresional Liason Committee member
 
National Association of Biology Teacher (NABT)  
Phi Beta Kappa (fBK)  
   

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Phone number: (704) 894-2889
Send comments, questions, and suggestions to: kabernd@davidson.edu