Genetically Modified Organisms
Fall 2004 Syllabus



We will be reading journal articles in this seminar. There is no textbook.
Readings will be provided in class, as links from this page/ homepage, or as PDF files on Blackboard

Readings and Assignments
(Note: Many are due outside of our meeting time)

Week of Jan 12
Blackboard Survey DUE by Noon Wednesday Jan14th
Reading for first class: Will Frankenfood Save the Planet? by J. Rauch
The Atlantic Monthly, October 2003 http://www.theatlantic.com/issues/2003/10/rauch.htm
In Class: 1) Introduction to Course and Blackboard uses
2)What is a GMO? Discuss Rauch paper and Background on Breeding vs Transgenics
3) Intro to 'GM people' Biography assignment--
4)Develop Webpage evaluation standard scale. You will use scale we developed to critique one student webpage from this site: http://www.bio.davidson.edu/people/midorcas/animalphysiology/hottopics.htm
Before leaving sign up for webpage you will critique
Week of Jan 19
Webpage critique DUE 10pm Monday Jan 19th : email word document to me
Assignment for class Thursday Jan22:
1) Begin looking for resources for GM people assignment
In Class: MEET IN LITTLE LIBRARY 1-2pm
1) In Little: Search engines and resources (with Frank Molinek, Science librarian)
2) In Wat247: Revise webpage evaluation scale, if necessary
3) Web workshop in Watson 247
Week of Jan 26
'GM people' Web Page Posted by 10pm Monday Jan 26th

Assignment for class Thursday Jan29:
1)Present your biography to class (approx 5min, oral, no computer)
2) 'GMO events' Identify a list of three controversial events as possible project topics: scientific developments, activist actions (on pro or con side), government actions.
List turned in at beginning of class
3) Reading:
Genetically Modified Crops Webpage: P. Lowry and L Powell: http://www.bio.davidson.edu/people/kabernd/seminar/2002/tech/Index.htm
Read Intro page, methods page(+three methods links within this page), Biotech breeding page
Plant Breeding Webpage: Megan Estes
http://www.bio.davidson.edu/people/kabernd/seminar/2002/method/meghan/me.htm

In Class:
1) What is a GMO? Comparison of Traditional and Genetic engineering approaches.
2) GM biography presentations
3) Sign up for GM events topic: you will create a small website that introduces and covers different angles of this topic. (3-4 pages of content plus an additional page for the bibliography)

Week of Feb 2

Three source annotated bibliography on your GM event: DUE midnight Monday Feb2nd: email word document to me.

Assignment for class Thurs Feb 5:
1) Prepare a list of two possible topics for larger project: These should be relatively broad topics that could have at least three different areas to study within them.
Hand in list at beginning of class
2) Readings:
--How to make Transgenic Plants: UNL Department of Agronomy http://www.colostate.edu/programs/lifesciences/TransgenicCrops/animation.html
Click on each step to view six different animations covering the process
-- Getting Started in Plant Tissue Culture by Michael H. Renfroe: http://www.jmu.edu/biology/pctc/tcstart.htm
--Cloning Plants by tissue culture by Michael H. Renfroe http://www.jmu.edu/biology/biofac/facfro/cloning/cloning.htm Read all three parts
--How do we develop transgenic plants: Saskatchewan Agricultural Biotechnology Information Centre
http://www.agwest.sk.ca/sabic_index_tp.shtml

In Class:
1) How do you genetically modify a plant? Transgenics and molecular techniques
2) Adding Agriculturally favorable traits: What traits do farmers want, what are traditional and GM ways of achieving them?
3) Establish groups for projects.
Note: Each group of three will be responsible for presenting background information on that topic, for picking two articles and leading class discussion of them and for preparing a group website on the topic. Each person will then prepare a final paper that covers one aspect of the topic more deeply. Think of your topics with this in mind.

Week of Feb 9
GM event website Posted by midnight Wednesday Feb 11th
No class Thursday Feb 12th
Week of Feb 16
 
Three Annotated references on project topic (from each person) DUE 10pm Monday Feb 16th email document to me.
Assignments for class Thurs Feb 19:
Readings on Blackboard:
A.M. Shelton et al. 2002. Economic, ecological, food safety and social consequences of the deployment of Bt transgenic plants. Annu. Rev. Entomol 47: 845-81

Zhao, J-Z. et al. 2003 Transgenic plants expressing two Bacillus thuringiensis toxins delay insect resistance evolution. Nature Biotechnology 21: 12 1493-1497.
In class:
1) Pesticide resistance through Bt: Discussion of articles
2) Introduction to 'escaping organisms'
Week of Feb 23
 
Three Annotated references on project topic (from each person) DUE 10pm Monday Feb 23th add to previous list and email document to me.

Assignments for class Thurs Feb 26:
1) Readings on Blackboard:
N. V. Federoff. 2003. Prehistoric GM Corn. Science 302: 1158-1159.

Pew Initiative on Food and Biotechnology. Aug. 2003. Have transgenes will travel.
1-15.

C.N. Stewart Jr., et al. 2003. Transgene introgression from genetically modified crops to their wild relatives. Nature Reviews Genetics 4: 806-817

2) Each group brings hard copy of three possible articles for discussion.
3) Each person brings a paragraph describing possibilities for final paper topic

In class:
1) Is lateral gene transfer something new? something to worry about? should we have a blanket policy or case by case review? Discussion of articles
2) Meet with me to discuss final paper topic

Week of Mar 1
  SPRING BREAK
Week of Mar 8
 
Members of Groups 2,3 and 4: Three Annotated references (per person) DUE 10pm Tuesday Mar 9 add to previous list and email document to me.
Assignments for class Thurs Mar 11:
1) Readings on Blackboard:
H. Daniell. 2002. Molecular stategies for containment in transgenic crops. Nature Biotechnology 20: 581-586

Pew Initiative on Food and Biotechnology Dec 2002. Future Fish: Issues in science and regulation of transgenic fish.11-28 and 57-58
In class:
If GM can make them pest resistant/ bigger/ etc can GM contain them? What about organisms that can move?-- GM fish

Group 1 Powerpoint presentation of background information on Medicinal Uses of GMOs
J. Antoon. D.Cheuy, and W. Wood

Week of Mar 15
 
Members of Groups 3 and 4: Three Annotated references (per person) DUE 10pm Monday Mar 15 add to previous list and email document to me.
Assignments for class Thurs Mar 18:
1) Reading: Group 1's papers
Cohen, E. 2001. Genetically modified monkey could be key to curing some diseases. www.cnn.com/2001/Health/01/11/green.monkey.02/index.html

Gott, M. 2002. Ethical Issues relating to transgenic animal production. ANZCCART News 15:1-4.

Larrick, JW, and Thomas, DW. 2001. Producing proteins in transgenic plants and animals. Curr Opin Biotech. 12: 411-418

In Class:
1) Discuss Group 1's papers

Group 2 Powerpoint presentation of background information on Using GM to Increase Crop's Nutritional Value
A. Cain, W. Greendyke and L. Hoskins
Week of Mar 22
 
Members of Groups 1 and 4: Three Annotated references (per person) DUE 10pm Monday Mar 22 add to previous list and email document to me.
Assignments for class Thurs Mar 25:
1) Reading: Group 2's papers
Kishore, G. and Shewmaker, C. 1999. Biotechnology: Improving human nutrition in developing and developed worlds. PNAS 96: 5968-5972.

Chong, M. 2003. Acceptance of Golden Rice in the Phillipine 'Rice Bowl'. Nature Biotech. 21: 971-972

Ania, T. et al. 2003. Improvement of rice (Oryza sativa L.) seed oil quality through introduction of a soybean microsomal omega-3 fatty acid desaturase gene. Plant Cell Rep 21: 988-992
In Class:1) Discuss Group 2's papers
Group 3 Powerpoint presentation of background information on GM Organisms and Their Effect on the Environment
H. Nguyen, K. Saunders, and C.Wrobleski
Week of Mar 29
 
Members of Groups 1 and 2: Three Annotated references (per person) DUE 10pm Monday Mar 29 add to previous list and email document to me.
Assignments for class Thurs Apr1:
1) Reading: Group 3's papers
Martello, Angela.1991 Bioremediation: Cleaning up with Biology and Technology. The Scientist 5[1]:0

Hong-Xia Zhang; Joanna N. Hodson; John P. Williams; Eduardo Blumwald (2001) Engineering Salt-Tolerant Brassica Plants: Characterization of Yield and Seed Oil Quality in Transgenic Plants with Increased Vacuolar Sodium Accumulation. PNAS 98:12832-12836.
In Class:
1) Discuss Group 3's papers
Group 4 Powerpoint presentation of background information on Using GM to Increase Crop Viability: A Farmer's Dream?
N. Hesson, M. Talbert, and S. Parker
Week of Apr 5
 
Members of Groups 1,2 and 3: Three Annotated references (per person) DUE 10pm Tuesday Apr 6 add to previous list and email document to me.
Assignments for class Thurs Apr 8:
1) Reading: Group 4's papers
C.U. Engineers New Rice Strain by Phillip Lane, Cornell Daily Sun, November 26, 2002

Crisis in the Cupboard: Big Threats to the World's Crops. Africa News Service, November 12, 2003
In Class:
1) Discuss Group 4's papers
2) Web workshop for Group website projects.
Week of Apr 12
 
Group Website Posted by Midnight Wednesday Apr 14

In Class:
1) Website Introductions: Each group give a tour of your work.
2) Each person present overview of the of the focus of your final paper and what you have developed thus far.
3) Webwork (explained that day)

Week of Apr 19
 
Hard copy of rough draft or detailed outline of final paper, DUE at beginning of class
Final Discussion and Wrap up
Week of Apr 26
 
FINAL PAPER Posted by Midnight Thursday Apr 29 (link from website)
Be sure it is in traditional term paper format (not a 'bulletted' 'subheadinged' webpage)


© Copyright 2004 Department of Biology, Davidson College, Davidson, NC 28035
Background images are from the Oregon State, and ASPB websites
Send comments, questions, and suggestions to: kabernd@davidson.edu