BIO 111 - Molecules, Genes, and Cells
Dr. Haynes - Spring 2008

Lecture Schedule

Class meets every Monday, Wednesday and Friday, 9:30 am - 10:20 am
in Chambers, Room 1006

Unit One: Cell Biology

Day Topic Reading Assignment
M, Jan 14 Course Introduction
Link: Complete the VARK Survey
Links: Syllabus and Assignment Help Guide
Link: Can you name any cell parts and processes in this animation?
W, Jan 16 Unit I: Cellular Communication
The Liver Produces Glucose In Response To Stress

Study Guide: 1 - 7 (stop at "We are now ready to put...")
Links: 3-D structures - Carbohydrates, protein alpha helix and beta strand, lipid bilayer, cAMP vs. ATP, G protein w/ GTP, G protein w/ GDP
F, Jan 18 The Liver Produces Glucose In Response To Stress
continued
*Clicker Quiz 1* (moved to Wed.)
Study Guide: 7 - 12 (stop at "How the Heart Pounds...")
M, Jan 21 MLK HOLIDAY (no class) none
W, Jan 23 How The Heart Pounds In Response To Stress
*Clicker Quiz 1*

Study Guide: 12 - 18 (stop at "OK. let's get back to the myocardial cell.")
Links: Ca2+ ion channel, Ca pump in the SR, Ca pump cycle
F, Jan 25 No class (conference out of town)
none
M, Jan 28 How The Heart Pounds In Response To Stress
continued
Study Guide: 18 - 20 (stop at "How Neurons Signal...")
Link: myosin cycle, Ca2+ regulation of myosin binding, muscle contraction
W, Jan 30 How Neurons Signal Muscles to Contract Study Guide: 20 - 25 (stop at "Action potentials are very fast...")
Link: Fun visual metaphor for action potential
Link: Nerve terminus in color
F, Feb 1 How Neurons Signal Muscles to Contract
continued
*Clicker Quiz 2*
Study Guide: 25 - 29 (stop at "How an Egg Learns...")
Link: Can you identify vesicle movement and exocytosis in this animation?
M, Feb 4 How An Egg Learns It Has Been Fertilized Study Guide: 29 (the second p. 29) - 35 (stop at "Other Cellular Communication...")
Link: pronuclei fusing
W, Feb 6 Other Cellular Communication Systems
*Clicker Quiz 3*
Study Guide: 35 - 38
Links: Gel electrophoresis figures and animation, calculating molecular weights, proteins in perspective, antibody structure, immunofluorescence, Western blot method
F, Feb 8 EXAM 1: take home portion
Due Monday Feb 11 in class
Prepare questions for in-class review session
M, Feb 11 EXAM 1: in class portion none

Unit Two: Genetics

Day Topic Reading Assignment
W, Feb 13 Unit II: Genetics
Intro. to three genetic diseases
Study Guide: 39 - 42 (stop at "What can we tell...")
Links: 3-D structures - dsDNA, ATP, DNA polymerase in action
Links: Movies - plant mitosis, animal mitosis, yeast (fungi) mitosis
F, Feb 15 Unit II: Genetics
Classical genetics
*Clicker Quiz 4*
Study Guide: 42 - 46 (stop at "We need to stop and look...")
Links: karyotyping activity
M, Feb 18 Unit II: Genetics
Classical genetics, continued
Study Guide: 46 - 50 (stop at "When we talk about mutations...")
Links: DNA replication animations - front view, back left view, back right view, overhead view
Link: chromosome packing animation
W, Feb 20 Unit II: Genetics
Molecular genetics
Study Guide: 50 - 55 (stop at "While we do not understand...")
Links: genetic code, transcription animation, SRY 3-D structure, translation movie
Link: Can you identify translation in this animation?
F, Feb 22 Unit II: Genetics
Molecular genetics, continued
*Clicker Quiz 5*
Study Guide: 55 - 60 (stop at "Investigators working on specific diseases...")
Link: hemoglobin tetramer
M, Feb 25 Unit II: Genetics
Molecular traits of three genetic diseases
Study Guide: 60 - 66 (stop at "In recent years, DNA fingerprinting...")
W, Feb 27 EXAM 2: take home portion
Due Friday, Feb 29 in class
Prepare questions for in-class review session
F, Feb 29 EXAM 2: in class portion none
M, Mar 3 SPRING BREAK (no class) none
W, Mar 5 SPRING BREAK (no class) none
F, Mar 7 SPRING BREAK (no class) none
M, Mar 10 Unit II: Genetics
Cloning disease genes
Study Guide: 66 - 74 (stop at "The search for the CF gene had been...")
Link: Linkage with RFLP markers and CF alleles
W, Mar 12 Unit II: Genetics
Cloning disease genes, continued
Study Guide: 74 - 77 (stop at "The DNA encoding the wild-type allele at the...")
Links: ddATP structure, dideoxy DNA sequencing, cycle sequencing, reverse transcriptase (stop when dsDNA is completed), Genome Browser exploration for CFTR
F, Mar 14 Unit II: Genetics
Cloning disease genes, continued
*Clicker Quiz 6*
Study Guide: 77 - 80 (stop at "If our initial hypothesis is not...")
M, Mar 17 Unit II: Genetics
Molecular traits of three genetic diseases
Study Guide: 80 - 83 (stop at "Huntingdon's - A Dominant Neurodegenerative Disease")
W, Mar 19 Huntingdon's - A Dominant Neurodegenerative Disease Study Guide: 83 - 86
Links: Hunting for Huntingdon's Disease, HD pedigree
F, Mar 21 Sex-linked Genetic Disorders
*Clicker Quiz 7 (survey)*
Study Guide: 87 - 88
M, Mar 24 EASTER BREAK (no class) none
W, Mar 26 MINI-EXAM: take home portion
Due Friday, Mar 28 in class
Prepare questions for in-class review session
F, Mar 28 MINI-EXAM: in class portion none

Unit Three: Bioenergetics

Day Topic Reading Assignment
M, Mar 31 Unit III: Bioenergetics
Question #1: The US Government vs. Mexican Marijuana Farmers
Study Guide: 89 - 95 (stop at "Chlorophyll harvests light energy by passing...")
Link: Chlorophyll structure
W, Apr 2 Harvesting Energy & Generating O2 Study Guide: 95 - 99 (stop at "Synthesizing Food: The Calvin Cycle")
Link: 3-D structures of photosynthesis
F, Apr 4 Synthesizing Food: The Calvin Cycle
*Clicker Quiz 8*

Study Guide: 99 - 103 (stop at "Question #2: Why is Cyanide Poisonous?")
Link: the complete Calvin Cycle (in case you're curious); paraquat structure

M, Apr 7 Question #2: Why is Cyanide Poisonous? Study Guide: 103 - 107 (stop at "Look over the steps in glycolysis...")
W, Apr 9 Question #2: Why is Cyanide Poisonous?
continued
Study Guide: 107 - 109 (stop at "ATP synthesis in photosynthesis and oxidative...")
Link: Glycolysis
F, Apr 11 Question #2: Why is Cyanide Poisonous?
continued
*Clicker Quiz 9*
Study Guide: 109 - 112 (stop at "Question #3: Why Update...")
Link: cyanide structure
M, Apr 14 Question #3: Why Update Your Vaccinations After a Flood?
Question #4: Why Is Tofu A Good Source Of Protein?

EXAM 3: take home portion
Due Wednesday, Apr 16 in class

Study Guide: 112 - 117 (stop at "Two Research Questions...")
Links: Tofu Pups, Rhizobium nodules, Clostridium affects neurotransmitter release
W, Apr 16 EXAM 3: in class portion none

Unit Four: Current Topics: Cancer, HIV/AIDS, & Genetic Engineering

Day Topic Reading Assignment
F, Apr 18 Cancer
*Clicker Quiz 10 (pre-survey)*
Study Guide: 119 - 123 (stop at "What do we know now about cell division that...)
Links: MRI's of tumors, cancer statistics, does smoking cause cancer?
M, Apr 21 Cancer
continued
Study Guide: 123 - 127 (stop at "In order to illustrate some of the normal...")
Links: Animations - Cancer Quest, Inside Cancer
W, Apr 23

Cancer
continued

Study Guide: 127 - 132 (stop at "AIDS & HIV")
Links: ras protein (color figure), practice case studies
F, Apr 25 AIDS & HIV
*Clicker Quiz 11*
Study Guide: 132 - 140 (stop at "Treatments for HIV and AIDS")
Links: WBC phagocytosis, B cell antibody production, antibody structure, HIV life cycle and treatments, Inspi(RED): HIV Positive Davidson student dance by Alana Ford
M, Apr 28 AIDS & HIV
Treatments for HIV and AIDS
Study Guide: 140 - 148 (stop at "Diagnosis of HIV+ Individuals")
Link: HIV treatment and Drug Resistance
Link: The narrated version of this animation explains how a white blood cell targets a site of infection.
W, Apr 30 AIDS & HIV
Diagnosis of HIV+ Individuals
Study Guide: 148 - 152 (stop at "Genetic Engineering")
Links: Baye's Rule for genetic testing, reliability of HIV test results, Western blot method, HIV debate
F, May 2 Genetic Engineering
*Clicker Quiz 12 (post-survey)*
Study Guide: 152 - 156
Links: Somatic Cell Nuclear Transfer in sheep, nonidentical clones?, biopharmaceuticals
M, May 5 Review
Course evaluations
Prepare questions for in-class review session
W, May 7

FINAL EXAM: in class portion
Revised Written Report 3 due

FINAL EXAM: take home portion
Due Monday, May 12 at 12 noon in my office

End of classes for Spring 2008

none
M, May 12 Turn in take home exam before 12 noon
Have a great Summer!

 

Davidson Academic Calendar - http://www3.davidson.edu/cms/x7693.xml