Educational Goals and Learning Outcomes

Cloning Disease Genes

Educational Goals:

Understand how to isolate disease-causing alleles and their wild-type counterparts.
Learn to manipulate genomic databases.
Apply molecular information to explain genetic diseases.

Learning Outcomes - Students will:

explain why a particular mutation is dominant or recessive
interpret RFLP data to identify DNA fragments containing disease alleles
design experiments to determine which step in protein production may be at fault for a particular disease.
describe the molecular causes for CF and HD
mine genomic databases for detailed information about any given gene/protein