Genomics @ Davidson

Home

In 1953, two young scientists published the structure of DNA, a Nobel Prize winning discovery that gave birth to the interdisciplinary field of genomics. Beginning in 1990, scientists around the world embarked upon the Human Genome Project, with the goal of determining the composition of the entire human genome. The project is now complete, but there is so much more to learn from the genome: how our bodies function, how to prevent diseases, what makes different species unique, and even how life evolved on earth.

To ensure that future scientists, physicians and policymakers are prepared to take full advantage of the genomic revolution, the National Research Council issued a report (Bio 2010) calling upon academic institutions to alter the way undergraduates prepare for post-baccalaureate education. Davidson College has responded to the call with Genomics and Bioinformatics courses, an interdisciplinary concentration, and interdisciplinary research opportunities for undergraduates.

Courses

BIO 309
Genomics with Lab

BIO / CSC 310
Bioinformatics

Concentration

The genomics concentration fulfills National Research Council recommendations to provide undergraduates with a strong foundation in biological, mathematical, physical and information sciences. The diverse academic background provided by this concentration in the context of a liberal arts education will help prepare students of all majors for exciting fields such as drug discovery, pharmaceutical industry, biomedical sciences, patent law, and ethics.

Requirements

The genomics concentration requires six courses (only five courses if Bio309 is offered with a lab) that meet the criteria below, with no more than two courses "double counting" for the concentration and a student's major. No more than three of these courses may be listed under any single department or prefix (i.e. CSC). No more than one of these courses can be taken pass/fail. A maximum of one transfer credit can be applied towards the concentration if approved by the advisors.

1) Three required courses: Bioinformatics (CSC310); Genomics, Proteomics and Systems Biology (Bio309); and Laboratory Methods in Genomics (Bio343). If a student successfully completed Bio309 with a lab, then Bio343 is not required.

2) Three courses from the list below. However, no more than two of these three courses can come from a single prefix (Department or CSC). The purpose of this requirement is to foster additional diversity in a student's curriculum. Because of their similarity, either CSC121 or Phy200 can be applied towards the concentration, but not both.

Application Procedure

Students interested in pursuing a genomics concentration should contact one of the two primary advisors (Drs. Malcolm Campbell and Laurie Heyer) as early as possible to discuss curriculum options. Those who decide to pursue the concentration must meet with the genomics advisors no later than the last day of the spring term in their junior year. Certification of completion of all requirements for the concentration is made by the registrar upon the recommendation of the genomics advisory committee.

Course Numbers and Titles

Biology

  • 301 Genetics
  • 302 Microbiology
  • 303 Biochemistry
  • 304 Molecular Biology
  • 306 Developmental Biology
  • 308 Cell Biology
  • 351 or 352 approved sections of Group Investigation
  • 371, 372, or 373 approved sections of Independent Study

Chemistry

  • 303 Bioorganic Chemistry
  • 306 Biophysical Chemistry
  • 309 Medicinal Chemistry
  • 371 Instrumental Analysis
  • 450 Advanced Biochemistry

Computer Science

  • 121 Programming and Problem Solving
  • 231 Data Structures or *321 Data Structures and Algorithms
  • 323 Object-oriented Programming or *223 Introduction to Object-oriented Programming
  • 331 Design and Analysis of Algorithms
  • 395 or 396 approved sections of Independent Study
    *These courses are no longer offered but are acceptable substitutions.

Mathematics

  • 210 Mathematical Modeling
  • 235 Differential Equations and Infinite Series
  • 340 Probability
  • 341 Mathematical Statistics
  • 360 Introduction to Topology
  • 391 or 392 or 491 or 492 approved sections of Independent Study

Physics

  • 200 Computational Physics
  • 201 Mathematical Methods for Scientists
  • 310 Electronics and Instrumentation
  • 397 Independent Study in Advanced Software Development in Science

Psychology

  • 276 Cognitive Psychology
  • 282 Learning or 305 Psychological Research – Learning
  • 284 Drugs and Behavior
  • 301 Psychological Research – Perception and Attention
  • 302 Psychological Research – Behavioral Pharmacology
  • 303 Psychological Research – Behavioral Neuroscience
  • 304 Psychological Research – Memory
  • 310 Psychological Research – Design and Analysis
  • 324 Advanced Neuroscience

 

Research

Students can pursue independent or group research projects. Group projects typically involve both biology majors and math majors. Independent projects are tailored to the student's interests, and may emphasize biological, mathematical and/or computational methods.

Research topics fall into one of the following areas:

Synthetic Biology

Synthetic biology is a new area of genomics that blends molecular biology with mathematics, computer science, and engineering. The goals of synthetic biology are to design and construct new biological parts, devices and systems for useful purposes. Davidson College undergraduate teams regularly compete in the international Genetically Engineered Machines (iGEM) jamboree.

News & Notes

DNA Microarrays

The DNA microarray is a high-throughput genomics method for measuring the expression levels of all genes in an organism simultaneously. Watch this animation to see how they work. Students design and build their own "teaching chips" in the Genomics Lab course, and several students have used microarrays in their independent studies or honors thesis projects. Other students have written software, called MAGIC Tool, to analyze gene expression data.

News & Notes