LOCUS 547967 1829 aa 01-FEB-1996
DEFINITION DILUTE MYOSIN HEAVY CHAIN, ISOFORM I (MYOSIN HEAVY CHAIN P190) (MYOSIN-V).
ACCESSION 547967 PID g547967 DB
SOURCE SWISS-PROT: locus MYSD_CHICK, accession Q02440 class: standard. created: Jun 1, 1994. sequence updated: Jun 1, 1994. annotation updated: Feb 1, 1996. xrefs: gi: 63364, gi: 63365, gi: 63737
KEYWORDS MYOSIN; REPEAT; ATP-BINDING; CALMODULIN-BINDING; ACTIN-BINDING; HEPTAD REPEAT PATTERN; COILED COIL; PHOSPHORYLATION.
SOURCE chicken.
ORGANISM Gallus gallus Eukaryotae; Metazoa; Chordata; Vertebrata; Archosauria; Aves; Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
REFERENCE 1 (residues 1 to 1829)
AUTHORS Sanders,G., Lichte,B., Meyer,H.E. and Kilimann,M.W. TITLE cDNA encoding the chicken ortholog of the mouse dilute gene product. Sequence comparison reveals a myosin I subfamily with conserved C-terminal domains
JOURNAL FEBS Lett. 311 (3), 295-298 (1992)
MEDLINE 93012002
REMARK SEQUENCE FROM N.A. TISSUE=BRAIN REFERENCE 2 (residues 1 to 1829) AUTHORS Espreafico,E.M., Cheney,R.E., Matteoli,M., Nascimento,A.A., De Camilli,P.V., Larson,R.E. and Mooseker,M.S. TITLE Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains
JOURNAL J. Cell Biol. 119 (6), 1541-1557 (1992)
MEDLINE 93107155
REMARK SEQUENCE FROM N.A., AND SEQUENCE OF 1154-1163. TISSUE=BRAIN COMMENT [SUBUNIT] MAY BE A HOMODIMER, WHICH ASSOCIATES WITH MULTIPLE CALMODULIN OR MYOSIN LIGHT CHAINS. [SUBCELLULAR LOCATION] GOLGI-DERIEVED CYTOPLASMIC MEMBRANES (POTENTIAL). [TISSUE SPECIFICITY] NEURONAL AND NONNEURONAL CELLS OF THE BRAIN. [SIMILARITY] BELONGS TO CLASS-5 MYOSINS.
FEATURES Location/Qualifiers source 1..1829 /organism="Gallus gallus" /db_xref="taxon:9031" Region 1..767 /note="HEAD." /region_name="Domain" Protein 1..1829 /product="DILUTE MYOSIN HEAVY CHAIN, ISOFORM I" Site 163..170 /note="ATP." /site_type="np-binding" Region 644..666 /note="ACTIN-BINDING." /region_name="Domain" Region 768..914 /note="NECK." /region_name="Domain" Region 774..788 /note="CALMODULIN-BINDING." /region_name="Domain" Region 797..811 /note="CALMODULIN-BINDING." /region_name="Domain" Region 822..836 /note="CALMODULIN-BINDING." /region_name="Domain" Region 845..863 /note="CALMODULIN-BINDING." /region_name="Domain" Region 870..885 /note="CALMODULIN-BINDING." /region_name="Domain" Region 893..907 /note="CALMODULIN-BINDING." /region_name="Domain" Region 915..1041 /note="COILED COIL." /region_name="Domain" Region 1042..1829 /note="TAIL." /region_name="Domain" Region 1142 /note="E -> EQ (IN REF. 2)." /region_name="Conflict" Site 1734 /site_type="phosphorylation"
ORIGIN 1 maaselytky arvwipdpee vwksaellkd ykpgdkvlql rleegkdley cldpktkelp 61 plrnpdilvg endltalsyl hepavlhnlk vrfidskliy tycgivlvai npyeqlpiyg 121 ediinaysgq nmgdmdphif avaeeaykqm ardernqsii vsgesgagkt vsakyamryf 181 atvsgsasea nveekvlasn pimesignak ttrndnssrf gkyieigfdk ryriiganmr 241 tylleksrvv fqaeeernyh ifyqlcasaa lpefktlrlg nanyfhytkq ggspvidgid 301 dakemvntrq actllgisds yqmgifrila gilhlgnvef asrdsdscai ppkhdpltif 361 cdlmgvdyee mahwlchrkl atatetyikp isklhainar dalakhiyan lfnwivdhvn 421 kalhstvkqh sfigvldiyg fetfeinsfe qfcinyanek lqqqfnmhvf kleqeeymke 481 qipwtlidfy dnqpcinlie akmgvldlld eeckmpkgsd dtwaqklynt hlnkcalfek 541 prlsnkafii khfadkveyq cegfleknkd tvyeeqikvl ksskkfkllp elfqdeekai 601 sptsatpsgr vplsrtpvkp akarpgqtsk ehkktvghqf rnslhllmet lnattphyvr 661 cikpndfkfp ftfdekravq qlracgvlet irisaagfps rwtyqeffsr yrvlmkqkdv 721 lsdrkqtckn vleklildkd kyqfgktkif fragqvayle kiradklraa ciriqktirg 781 wlmrkkymrm rraaitiqry vrghqarcya tflrrtraai iiqkfqrmyv vrkryqcmrd 841 atialqallr gylvrnkyqm mlrehksiii qkhvrgwlar vhyhrtlkai vylqccyrrm 901 makrelkklk iearsveryk klhiglenki mqlqrkideq nkeyksllek mnnleityst 961 eteklrsdve rlrmseeeak natnrvlslq eeiaklrkel hqtqtekkti eewadkykhe 1021 teqlvselke qntllkteke elnrrihdqa keitetmekk lveetkqlel dlnderlryq 1081 nllnefsrle eryddlkdem nlmvsipkpg hkrtdsthss neseytfsse iteaedlplr 1141 meepsekkap ldmslflklq krvteleqek qslqdeldrk eeqalrakak eeerppirga 1201 eleyeslkrq elesenkklk nelnelqkal tetrapevta pgapayrvll dqltsvseel 1261 evrkeevlil rsqlvsqkea iqpkedkntm tdstilledv qkmkdkgeia qayiglketn 1321 rllesqlqsq kksheneles lrgeiqslke ennrqqqlla qnlqlppear ieaslqheit 1381 rltnenldlm eqlekqdktv rklkkqlkvf akkigelevg qmenispgqi idepirpvni 1441 prkekdfqgm leykkedeqk lvknlilelk prgvavnlip glpayilfmc vrhadylndd 1501 qkvrslltst ingikkvlkk rgddfetvsf wlsntcrflh clkqysgeeg fmkhntprqn 1561 ehcltnfdla eyrqvlsdla iqiyqqlvrv lenilqpmiv sgmlehetiq gvsgvkptgl 1621 rkrtssiade gtytldsiir qlnsfhsvmc qhgmdpelik qvvkqmfyii gavtlnnlll 1681 rkdmcswskg mqirynvsql eewlrdknlm nsgaketlep liqaaqllqv kkktdedaea 1741 icsmcnaltt aqivkvlnly tpvnefeerv lvsfirtiql rlrdrkdspq llmdakhifp 1801 vtfpfnpssl aletiqipas lglgfisrv //