This page was created for an undergraduate course at Davidson
College.
Ortholog Home Page
(Copy of a NCBI BLAStp Results Page)
BLASTP 2.2.2 [Dec-14-2001]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
RID: 1016205033-22230-5647
Query=
(420 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF
891,607 sequences; 279,182,324 total letters
If you have any problems or questions with the results of this search
please refer to the BLAST FAQs
Taxonomy reports
Sequences producing significant alignments: (bits) Value
gi|6324319|ref|NP_014389.1| (NC_001146) peroxisomal NADP-de... 821 0.0
gi|6323203|ref|NP_013275.1| (NC_001144) concerts isocitrate... 647 0.0
gi|736722|gb|AAA64516.1| (L26312) isocitrate dehydrogenase ... 611 e-174
gi|6320137|ref|NP_010217.1| (NC_001136) Mitochondrial form ... 578 e-164
gi|2541874|dbj|BAA22846.1| (AB007994) NADP-linked isocitrat... 571 e-162
gi|3023996|sp|O13285|IDHP_CANTR ISOCITRATE DEHYDROGENASE [N... 564 e-160
gi|15027826|gb|AAK76730.1| (AY040207) mitochondrial NADP-de... 561 e-159
gi|15027827|gb|AAK76731.1| (AY040207) peroxisomal NADP-depe... 555 e-157
gi|3023999|sp|P79089|IDHP_ASPNG ISOCITRATE DEHYDROGENASE [N... 551 e-156
gi|3747089|gb|AAC64182.1| (AF095445) NADP-dependent isocitr... 535 e-151
gi|17987074|ref|NP_539708.1| (NC_003317) ISOCITRATE DEHYDRO... 535 e-151
gi|2497259|sp|Q40345|IDHP_MEDSA ISOCITRATE DEHYDROGENASE [N... 533 e-151
gi|5007084|gb|AAD37809.1|AF155333_1 (AF155333) NADP-specifi... 533 e-150
gi|169989|gb|AAA33978.1| (L12157) NADPH-specific isocitrate... 531 e-150
gi|479386|pir||S33612 isocitrate dehydrogenase (NADP+) (EC ... 531 e-150
gi|16126761|ref|NP_421325.1| (NC_002696) isocitrate dehydro... 529 e-149
gi|417178|sp|Q04467|IDHP_BOVIN ISOCITRATE DEHYDROGENASE [NA... 528 e-149
gi|1708401|sp|Q06197|IDHC_SOYBN ISOCITRATE DEHYDROGENASE [N... 528 e-149
gi|1750380|gb|AAB39248.1| (U80912) NADP-isocitrate dehydrog... 528 e-149
gi|12003362|gb|AAG43538.1|AF212319_1 (AF212319) NADP+-speci... 527 e-149
gi|7431242|pir||T07402 probable isocitrate dehydrogenase (N... 526 e-148
gi|4504575|ref|NP_002159.1| (NM_002168) isocitrate dehydrog... 525 e-148
gi|5007086|gb|AAD37810.1|AF155334_1 (AF155334) NADP-specifi... 525 e-148
gi|1708409|sp|P50215|IDH_SPHYA ISOCITRATE DEHYDROGENASE [NA... 525 e-148
gi|15982950|gb|AAL11503.1|AF367443_1 (AF367443) NADP-depend... 525 e-148
gi|14328062|gb|AAH09244.1|AAH09244 (BC009244) isocitrate de... 525 e-148
gi|462384|sp|P33198|IDHP_PIG ISOCITRATE DEHYDROGENASE [NADP... 525 e-148
gi|3811009|dbj|BAA34113.1| (AB019328) NADP specific isocitr... 524 e-148
gi|1708400|sp|P50217|IDHC_SOLTU ISOCITRATE DEHYDROGENASE [N... 523 e-147
gi|15241443|ref|NP_196963.1| (NM_121463) isocitrate dehydro... 523 e-147
gi|5764653|gb|AAD51361.1|AF176669_1 (AF176669) NADP-isocitr... 522 e-147
gi|3811007|dbj|BAA34112.1| (AB019327) NADP specific isocitr... 522 e-147
gi|2623962|emb|CAA73139.1| (Y12540) isocitrate dehydrogenas... 522 e-147
gi|15965545|ref|NP_385898.1| (NC_003047) PROBABLE ISOCITRAT... 521 e-147
gi|1708402|sp|P50218|IDHC_TOBAC ISOCITRATE DEHYDROGENASE [N... 521 e-147
gi|7431245|pir||T04355 isocitrate dehydrogenase (NADP+) (EC... 521 e-147
gi|7431243|pir||T04356 isocitrate dehydrogenase (NADP+) (EC... 520 e-146
gi|8133104|gb|AAF73472.1|AF268076_1 (AF268076) NADP-depende... 519 e-146
gi|542060|pir||S42892 isocitrate dehydrogenase (NADP+) (EC ... 518 e-146
gi|15221788|ref|NP_175836.1| (NM_104312) NADP-isocitrate de... 518 e-146
gi|322709|pir||S28423 isocitrate dehydrogenase (NADP+) (EC ... 518 e-146
gi|15889170|ref|NP_354851.1| (NC_003062) AGR_C_3429p [Agrob... 517 e-146
gi|15610475|ref|NP_217856.1| (NC_000962) icd1 [Mycobacteriu... 514 e-145
gi|6680343|ref|NP_032348.1| (NM_008322) isocitrate dehydrog... 514 e-145
gi|1589591|prf||2211361A isocitrate dehydrogenase [Mus musc... 514 e-145
gi|17550822|ref|NP_509875.1| (NM_077474) Isocitrate and iso... 513 e-144
gi|15218869|ref|NP_176768.1| (NM_105265) isocitrate dehydro... 513 e-144
gi|5738864|emb|CAA63220.1| (X92486) isocitrate dehydrogenas... 512 e-144
gi|5042455|gb|AAD38292.1|AC007789_18 (AC007789) NADP-depend... 511 e-144
gi|13470357|ref|NP_101923.1| (NC_002678) NADP-dependent iso... 509 e-143
gi|13928690|ref|NP_113698.1| (NM_031510) isocitrate dehydro... 503 e-141
gi|6647567|sp|Q9Z2K9|IDHC_MICME ISOCITRATE DEHYDROGENASE [N... 502 e-141
gi|6647566|sp|Q9Z2K8|IDHC_MICOH ISOCITRATE DEHYDROGENASE [N... 501 e-141
gi|14729950|ref|XP_028869.1| (XM_028869) isocitrate dehydro... 499 e-140
gi|5174471|ref|NP_005887.1| (NM_005896) isocitrate dehydrog... 498 e-140
gi|11374664|pir||T46280 isocitrate dehydrogenase (NADP+) (E... 498 e-140
gi|6754278|ref|NP_034627.1| (NM_010497) isocitrate dehydrog... 497 e-140
gi|19115017|ref|NP_594105.1| (NC_003424) isocitrate dehydro... 496 e-139
gi|17540874|ref|NP_501665.1| (NM_069264) isocitrate dehydro... 496 e-139
gi|4959708|gb|AAD34457.1|AF136009_1 (AF136009) cytosolic NA... 496 e-139
gi|11320848|dbj|BAB18331.1| (AP002865) putative NADP-isocit... 488 e-137
gi|7295107|gb|AAF50433.1| (AE003555) CG7176 gene product [a... 484 e-136
gi|7295108|gb|AAF50434.1| (AE003555) CG7176 gene product [a... 482 e-135
gi|7295109|gb|AAF50435.1| (AE003555) CG7176 gene product [a... 482 e-135
gi|1277203|gb|AAC50455.1| (U52144) isocitrate dehydrogenase... 474 e-133
gi|15643905|ref|NP_228954.1| (NC_000853) isocitrate dehydro... 407 e-112
gi|4218518|emb|CAA76364.1| (Y16751) isocitrate dehydrogenas... 405 e-112
gi|17463070|ref|XP_068996.1| (XM_068996) hypothetical prote... 394 e-108
gi|5881128|gb|AAD55056.1| (AF173666) isocitrate dehydrogena... 319 4e-86
gi|12802049|emb|CAC29022.1| (AJ272113) isocitrate dehydroge... 318 8e-86
gi|1922272|emb|CAA65773.1| (X97063) isocitrate dehydrogenas... 259 3e-68
gi|1628569|gb|AAB17375.1| (U62389) putative cytosolic NADP-... 187 2e-46
gi|5001396|gb|AAD36990.1| (AF041471) NADP-dependent isocitr... 156 4e-37
gi|16305085|gb|AAL16965.1|AF367449_1 (AF367449) NADP-depend... 142 7e-33
gi|12003155|gb|AAG43470.1|AF197566_1 (AF197566) NADP+-speci... 65 2e-09
gi|16124448|ref|NP_419012.1| (NC_002696) 3-isopropylmalate ... 50 4e-05
gi|6322097|ref|NP_012172.1| (NC_001141) homo-isocitrate deh... 48 2e-04
gi|2497256|sp|Q59940|IDH_STRMU ISOCITRATE DEHYDROGENASE [NA... 48 2e-04
gi|15897626|ref|NP_342231.1| (NC_002754) 3-isopropylmalate ... 47 4e-04
gi|15604135|ref|NP_220650.1| (NC_000963) ISOCITRATE DEHYDRO... 46 6e-04
gi|18414179|ref|NP_568113.1| (NM_120407) putative protein [... 46 6e-04
gi|11251553|pir||T48350 3-isopropylmalate dehydrogenase-lik... 46 6e-04
gi|15615619|ref|NP_243923.1| (NC_002570) 3-isopropylmalate ... 45 0.001
gi|126197|sp|P24404|LEU3_AGRT5 3-isopropylmalate dehydrogen... 45 0.002
gi|15890038|ref|NP_355719.1| (NC_003062) AGR_C_5067p [Agrob... 45 0.002
gi|18151365|dbj|BAB83690.1| (AB022437) isocitrate dehydroge... 44 0.002
gi|15967063|ref|NP_387416.1| (NC_003047) PROBABLE 3-ISOPROP... 44 0.002
gi|15232762|ref|NP_187592.1| (NM_111816) putative isocitrat... 44 0.002
gi|1708803|sp|P50180|LEU3_NEILA 3-ISOPROPYLMALATE DEHYDROGE... 44 0.003
gi|15922493|ref|NP_378162.1| (NC_003106) 409aa long hypothe... 44 0.003
gi|16272925|ref|NP_439150.1| (NC_000907) 3-isopropylmalate ... 44 0.004
gi|6539562|dbj|BAA88179.1| (AP000836) ESTs C19133(E10008),A... 44 0.004
gi|16081283|ref|NP_393595.1| (NC_002578) probable isocitrat... 43 0.005
gi|15605790|ref|NP_213167.1| (NC_000918) 3-isopropylmalate ... 43 0.005
gi|15676918|ref|NP_274065.1| (NC_003112) 3-isopropylmalate ... 43 0.007
gi|18977312|ref|NP_578669.1| (NC_003413) 3-isopropylmalate ... 43 0.007
gi|15794359|ref|NP_284181.1| (NC_003116) putative 3-isoprop... 43 0.007
gi|15892276|ref|NP_359990.1| (NC_003103) isocitrate dehydro... 42 0.009
gi|7431333|pir||T03406 probable isocitrate dehydrogenase (N... 42 0.009
gi|7427677|pir||S30897 3-isopropylmalate dehydrogenase (EC ... 42 0.010
Alignments
>gi|6324319|ref|NP_014389.1| (NC_001146) peroxisomal NADP-dependent isocitrate dehydrogenase;
Idp3p [Saccharomyces cerevisiae]
gi|1708405|sp|P53982|IDHH_YEAST PUTATIVE ISOCITRATE DEHYDROGENASE [NADP] (OXALOSUCCINATE
DECARBOXYLASE) (IDH) (NADP+-SPECIFIC ICDH) (IDP)
gi|2117470|pir||S62921 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) IDP3 - yeast
(Saccharomyces cerevisiae)
gi|1301828|emb|CAA95869.1| (Z71285) ORF YNL009w [Saccharomyces cerevisiae]
Length = 420
Score = 821 bits (2121), Expect = 0.0
Identities = 420/420 (100%), Positives = 420/420 (100%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS
Sbjct: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL
Sbjct: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM
Sbjct: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ
Sbjct: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG
Sbjct: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE
Sbjct: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL 420
KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL
Sbjct: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL 420
>gi|6323203|ref|NP_013275.1| (NC_001144) concerts isocitrate and NADP+ to 2-oxoglutarate, CO2,
and NADPH; Idp2p [Saccharomyces cerevisiae]
gi|1708403|sp|P41939|IDHC_YEAST ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC (OXALOSUCCINATE
DECARBOXYLASE) (IDH) (NADP+-SPECIFIC ICDH) (IDP)
gi|1071806|pir||S51419 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) IDP2 precursor,
cytosolic - yeast (Saccharomyces cerevisiae)
gi|577204|gb|AAB67464.1| (U17246) Idp2p: isocitrate dehydrogenase [Saccharomyces cerevisiae]
Length = 412
Score = 647 bits (1670), Expect = 0.0
Identities = 311/404 (76%), Positives = 366/404 (89%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +PIVEMDGDEQTR+IW LI++KL+LPYLDVDLKYYDLS++ RD+TNDQVT DS
Sbjct: 1 MTKIKVANPIVEMDGDEQTRIIWHLIRDKLVLPYLDVDLKYYDLSVEYRDQTNDQVTVDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ ATLKYGVAVKCATITPDEAR++EF+LK+MWKSPNGTIRNILGGTVFREPIIIP+IPRL
Sbjct: 61 ATATLKYGVAVKCATITPDEARVEEFHLKKMWKSPNGTIRNILGGTVFREPIIIPRIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP WEKPIIIGRHAFGDQY+ATD+ + + G+LRL + S G ++DLKV+++P+ GG+AM
Sbjct: 121 VPQWEKPIIIGRHAFGDQYKATDVIVPEEGELRLVYKSKSGTHDVDLKVFDYPEHGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+NT DSI+GFAKASFELA++RKLPL+ TTKNTILK YD +FK +F+ ++ + YKEKF+
Sbjct: 181 MMYNTTDSIEGFAKASFELAIERKLPLYSTTKNTILKKYDGKFKDVFEAMYARSYKEKFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
+L I YEHRLIDDMVAQMLKSKGG+IIAMKNYDGDV+SDIVAQGFGSLGLMTS+LITPDG
Sbjct: 241 SLGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVESDIVAQGFGSLGLMTSVLITPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KTFESEAAHGTVTRHFR+HQ+G+ETSTNSIASIFAWTR IIQRGKLDNT DV+KFG +LE
Sbjct: 301 KTFESEAAHGTVTRHFRQHQQGKETSTNSIASIFAWTRGIIQRGKLDNTPDVVKFGQILE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
AT++TVQ G MTKDLAL+LGK+ RS+YVTTEEFID V RL+
Sbjct: 361 SATVNTVQEDGIMTKDLALILGKSERSAYVTTEEFIDAVESRLK 404
>gi|736722|gb|AAA64516.1| (L26312) isocitrate dehydrogenase [Saccharomyces cerevisiae]
Length = 411
Score = 611 bits (1576), Expect = e-174
Identities = 296/404 (73%), Positives = 352/404 (86%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +PIVEMDGDEQTR+IW ++KL+LPYLDVDLKYYDLS++ RD+TNDQVT DS
Sbjct: 1 MTKIKVANPIVEMDGDEQTRIIWSFNQDKLVLPYLDVDLKYYDLSVEYRDQTNDQVTVDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ ATLKY VAVKCATITPDEAR++EF+LK+MWKSPNGTIRNILGGTVFREPIIIP+IPRL
Sbjct: 61 ATATLKYRVAVKCATITPDEARVEEFHLKKMWKSPNGTIRNILGGTVFREPIIIPRIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP WEKPIIIGRHAFGDQY+ATD+ + + G+LRL + S G ++DLKV+++P+ GG+AM
Sbjct: 121 VPQWEKPIIIGRHAFGDQYKATDVIVPEEGELRLVYKSKSGTHDVDLKVFDYPEHGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N DSI+GFAKASFELA++RKLPL+ TTKNTILK YD +FK +F+ ++ + K +
Sbjct: 181 MMYNNTDSIEGFAKASFELAIERKLPLYSTTKNTILKKYDGKFKDVFEAMYLEVIKRSLE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
+L I YEHRLIDDMVAQMLKSKGG+I+AMKNYDGDV+SDIVAQGFGSLGLMTS+LITPDG
Sbjct: 241 SLGIWYEHRLIDDMVAQMLKSKGGYIMAMKNYDGDVESDIVAQGFGSLGLMTSVLITPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KTFES+ AHGTVTRH + +G ETSTNSIASIFAWTR IIQRGKLDNT DV+KFG +LE
Sbjct: 301 KTFESDRAHGTVTRHLTDYDKGRETSTNSIASIFAWTRGIIQRGKLDNTPDVVKFGQILE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
AT++TVQ G MTKDLAL+LGK+ RS+YVTTEEFID V RL+
Sbjct: 361 SATVNTVQEDGIMTKDLALILGKSERSAYVTTEEFIDAVESRLK 404
>gi|6320137|ref|NP_010217.1| (NC_001136) Mitochondrial form of NADP-specific isocitrate
dehydrogenase; Idp1p [Saccharomyces cerevisiae]
gi|124160|sp|P21954|IDHP_YEAST ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL PRECURSOR
(OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC
ICDH) (IDP)
gi|65943|pir||DCBYIS isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) precursor,
mitochondrial - yeast (Saccharomyces cerevisiae)
gi|171749|gb|AAA34703.1| (M57229) NADPH-specific isocitrate dehydrogenase [Saccharomyces
cerevisiae]
gi|1431074|emb|CAA98631.1| (Z74114) ORF YDL066w [Saccharomyces cerevisiae]
Length = 428
Score = 578 bits (1490), Expect = e-164
Identities = 286/410 (69%), Positives = 342/410 (82%), Gaps = 3/410 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
SKIKV P+VE+DGDE TR+IW IK+KLILPYLDVDLKYYDLS++ RD T+D++T+D++
Sbjct: 18 SKIKVKQPVVELDGDEMTRIIWDKIKKKLILPYLDVDLKYYDLSVESRDATSDKITQDAA 77
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KYGV +KCATITPDEAR+KEFNL +MWKSPNGTIRNILGGTVFREPI+IP+IPRLV
Sbjct: 78 EAIKKYGVGIKCATITPDEARVKEFNLHKMWKSPNGTIRNILGGTVFREPIVIPRIPRLV 137
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDD--GKENIDLKVYEFPKSGGIA 179
P WEKPIIIGRHA GDQY+ATD I G L L + D + LKVY++ K G+A
Sbjct: 138 PRWEKPIIIGRHAHGDQYKATDTLIPGPGSLELVYKPSDPTTAQPQTLKVYDY-KGSGVA 196
Query: 180 MAMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKF 239
MAM+NT++SI+GFA +SF+LA+ +KL LF +TKNTILK YD +FK IF +++ +YK KF
Sbjct: 197 MAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQYKSKF 256
Query: 240 QALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPD 299
+ L I YEHRLIDDMVAQM+KSKGGFI+A+KNYDGDVQSDIVAQGFGSLGLMTSIL+TPD
Sbjct: 257 EQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPD 316
Query: 300 GKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLL 359
GKTFESEAAHGTVTRH+RK+Q+GEETSTNSIASIFAW+R +++RG+LDNT + KF N+L
Sbjct: 317 GKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKRGELDNTPALCKFANIL 376
Query: 360 EKATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLS 409
E ATL+TVQ G MTKDLAL G RS+YVTTEEF+D V KRLQ + S
Sbjct: 377 ESATLNTVQQDGIMTKDLALACGNNERSAYVTTEEFLDAVEKRLQKEIKS 426
>gi|2541874|dbj|BAA22846.1| (AB007994) NADP-linked isocitrate dehydrogenase [Candida
tropicalis]
Length = 411
Score = 571 bits (1471), Expect = e-162
Identities = 283/403 (70%), Positives = 338/403 (83%), Gaps = 1/403 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+ KI V +PIVEMDGDE TR+IW+ IK+KLILPYL+VDLKYYDL I+ RD+T+D+VT D+
Sbjct: 4 IQKITVKNPIVEMDGDEMTRIIWQFIKDKLILPYLNVDLKYYDLGIEYRDKTDDKVTTDA 63
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A L+YGV VKCATITPDEAR+KEFNLK+MW SPNGT+RN++GGTVFREPI+I IPR+
Sbjct: 64 AEAILQYGVGVKCATITPDEARVKEFNLKKMWLSPNGTLRNVIGGTVFREPIVIDNIPRI 123
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP WEKPIIIGRHAFGDQY+ATD+ I AG L+L F DG E + VY+F G+A+
Sbjct: 124 VPSWEKPIIIGRHAFGDQYKATDVVIPAAGDLKLVFKPKDGGEVQEFPVYQF-DGPGVAL 182
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
+M+NT+ SI FA++SF+LA++RKL LF +TKNTILK YD +FK IF+ L+ +YK K
Sbjct: 183 SMYNTDASITDFAESSFQLAIERKLNLFSSTKNTILKKYDGKFKDIFEGLYASKYKTKMD 242
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
L I YEHRLIDDMVAQMLKSKGG+IIAMKNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 243 ELGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDG 302
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
K FESEAAHGTVTRH+R+HQ+G+ETSTNSIASI+AWTR +IQRGKLD+T +V+KF LE
Sbjct: 303 KAFESEAAHGTVTRHYRQHQQGKETSTNSIASIYAWTRGLIQRGKLDDTPEVVKFAEELE 362
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRL 403
KA ++TV MTKDLAL GKT+RSSYVTTEEFID VA RL
Sbjct: 363 KAVIETVSKDNIMTKDLALTQGKTDRSSYVTTEEFIDGVANRL 405
>gi|3023996|sp|O13285|IDHP_CANTR ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL PRECURSOR
(OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC
ICDH) (IDP)
gi|2564042|dbj|BAA22945.1| (AB004556) mitochondrial NADP-linked isocitrate dehydrogenase
[Candida tropicalis]
Length = 430
Score = 564 bits (1453), Expect = e-160
Identities = 272/402 (67%), Positives = 338/402 (83%), Gaps = 1/402 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVE+DGDE TR+IW+ IK++LILPYLDVDLKYYDL I+ RD T+DQ+T D++
Sbjct: 29 KIKVKNPIVELDGDEMTRIIWQKIKDQLILPYLDVDLKYYDLGIESRDATDDQITIDAAN 88
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A +YGV VKCATITPDEAR+KEF+LK+MW SPNGTIRNILGGTVFRE IIIP IPRL+P
Sbjct: 89 AIKEYGVGVKCATITPDEARVKEFHLKKMWLSPNGTIRNILGGTVFRESIIIPCIPRLIP 148
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
WEKPI+IGRHAFGDQY+ATD+ I + G+L L+F+ G E KVY++ G+ +AM
Sbjct: 149 GWEKPIVIGRHAFGDQYKATDLVINEPGRLELRFTPASGGEAQTQKVYDY-TGPGVGLAM 207
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA ASF++AL + LPL+ +TKNTILK YD +FK IF +++++Y +F+
Sbjct: 208 YNTDESITGFAHASFKMALAKGLPLYMSTKNTILKKYDGRFKDIFQQIYEQDYAAEFEKQ 267
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
+ YEHRLIDDMVAQM+KSKGGF++A+KNYDGDVQSDIVAQGFGSLGLMTS L+TPDGK
Sbjct: 268 GLWYEHRLIDDMVAQMIKSKGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSALMTPDGKA 327
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
+E+EAAHGTVTRH+R+HQ+G+ETSTNSIASIFAWTR + QRGKLD T DV+ F + LE+A
Sbjct: 328 YEAEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGLAQRGKLDETPDVVDFASKLEQA 387
Query: 363 TLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
T+DTV+V MTKDLAL +GKT+RS+YVTT EF+D VA RL+
Sbjct: 388 TIDTVEVDRIMTKDLALAMGKTDRSAYVTTTEFLDAVADRLK 429
>gi|15027826|gb|AAK76730.1| (AY040207) mitochondrial NADP-dependent isocitrate dehydrogenase
[Aspergillus nidulans]
Length = 493
Score = 561 bits (1446), Expect = e-159
Identities = 270/404 (66%), Positives = 331/404 (81%), Gaps = 2/404 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+ KIKV +P+VE+DGDE TR+IWK I+EKLILP+LD+DLKYYDL ++ RD+T+D+VT +S
Sbjct: 85 VQKIKVKNPVVELDGDEMTRIIWKEIREKLILPFLDIDLKYYDLGLEYRDQTDDKVTTES 144
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRL
Sbjct: 145 AEAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRL 204
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPIIIGRHAFGDQYRATD I GKL L ++ + G+ +KV++FP GG+
Sbjct: 205 VPGWTKPIIIGRHAFGDQYRATDRVIPGPGKLELVYTPEGGQPEA-IKVFDFP-GGGVTQ 262
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
+NT++SI+GFA ASF+LAL + LPL+ +TKNTILK YD +FK IF +F+ +YK++F
Sbjct: 263 TQYNTDESIRGFAHASFKLALTKGLPLYMSTKNTILKKYDGRFKDIFQEIFESDYKKEFD 322
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQM+KS+GGFI+A+KNYDGDVQSDIVAQGFGSLGLMTS LITPDG
Sbjct: 323 AKGIWYEHRLIDDMVAQMIKSEGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSTLITPDG 382
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
+ FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+KF LE
Sbjct: 383 QAFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVKFAEELE 442
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
+A +D V G MTKDLAL G+ R ++VTT E++ V +RL+
Sbjct: 443 RACIDVVNEEGIMTKDLALSCGRKERDAWVTTREYMAAVERRLR 486
>gi|15027827|gb|AAK76731.1| (AY040207) peroxisomal NADP-dependent isocitrate dehydrogenase
[Aspergillus nidulans]
Length = 413
Score = 555 bits (1431), Expect = e-157
Identities = 270/404 (66%), Positives = 331/404 (81%), Gaps = 2/404 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+ KIKV +P+VE+DGDE TR+IWK I+EKLILP+LD+DLKYYDL ++ RD+T+D+VT +S
Sbjct: 5 VQKIKVKNPVVELDGDEMTRIIWKEIREKLILPFLDIDLKYYDLGLEYRDQTDDKVTTES 64
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRL
Sbjct: 65 AEAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRL 124
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPIIIGRHAFGDQYRATD I GKL L ++ + G+ +KV++FP GG+
Sbjct: 125 VPGWTKPIIIGRHAFGDQYRATDRVIPGPGKLELVYTPEGGQPEA-IKVFDFP-GGGVTQ 182
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
+NT++SI+GFA ASF+LAL + LPL+ +TKNTILK YD +FK IF +F+ +YK++F
Sbjct: 183 TQYNTDESIRGFAHASFKLALTKGLPLYMSTKNTILKKYDGRFKDIFQEIFESDYKKEFD 242
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQM+KS+GGFI+A+KNYDGDVQSDIVAQGFGSLGLMTS LITPDG
Sbjct: 243 AKGIWYEHRLIDDMVAQMIKSEGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSTLITPDG 302
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
+ FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+KF LE
Sbjct: 303 QAFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVKFAEELE 362
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
+A +D V G MTKDLAL G+ R ++VTT E++ V +RL+
Sbjct: 363 RACIDVVNEEGIMTKDLALSCGRKERDAWVTTREYMAAVERRLR 406
>gi|3023999|sp|P79089|IDHP_ASPNG ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL PRECURSOR
(OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC
ICDH) (IDP)
gi|1778636|dbj|BAA19073.1| (AB000261) NADP-dependent isocitrate dehydrogenase precursor
[Aspergillus niger]
gi|1778638|dbj|BAA19074.1| (AB000262) NADP-dependent isocitrate dehydrogenase precursor
[Aspergillus niger]
Length = 498
Score = 551 bits (1419), Expect = e-156
Identities = 265/402 (65%), Positives = 327/402 (80%), Gaps = 2/402 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +P+VE+DGDE TR+IW+ I+EKLILPYLDVDLKYYDL ++ RD+T+DQVT +++
Sbjct: 92 KIKVKNPVVELDGDEMTRIIWQEIREKLILPYLDVDLKYYDLGLEYRDQTDDQVTVEAAE 151
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPIIIP IPRLVP
Sbjct: 152 AIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIIIPAIPRLVP 211
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPIIIGRHAFGDQYRATD I GKL L ++ +G+ +KVY+F + GGIA
Sbjct: 212 GWNKPIIIGRHAFGDQYRATDRVIPGPGKLELVYTPVNGEPET-VKVYDF-QGGGIAQTQ 269
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+GFA ASF++AL + LPL+ +TKNTILK YD +FK IF +++ Y++ F+A
Sbjct: 270 YNTDESIRGFAHASFQMALLKGLPLYMSTKNTILKRYDGRFKDIFQEIYESTYQKDFEAK 329
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
+ YEHRLIDDMVAQM+KS+GGF++A+KNYDGDVQSDIVAQGFGSLGLMTS L+TP G+
Sbjct: 330 NLWYEHRLIDDMVAQMIKSEGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSTLVTPTGEA 389
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+ F LE+A
Sbjct: 390 FESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVTFAEELERA 449
Query: 363 TLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
++ V G MTKDLAL G+ R ++VTT E++ V +RL+
Sbjct: 450 CIEVVNDEGIMTKDLALACGRKEREAWVTTREYMAAVERRLK 491
>gi|3747089|gb|AAC64182.1| (AF095445) NADP-dependent isocitrate dehydrogenase [Glycine max]
Length = 416
Score = 535 bits (1379), Expect = e-151
Identities = 265/413 (64%), Positives = 325/413 (78%), Gaps = 5/413 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KI+V +PIVEMDGDE TRVIWKLIK+KLI PYL++D+KY+DL + RD TND+VT +S+
Sbjct: 5 KIRVGNPIVEMDGDEMTRVIWKLIKDKLIFPYLELDIKYFDLGLPHRDATNDRVTIESAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDEAR+KEFNLK+MW+SPNGTIRNIL GTVFREPII IPRLV
Sbjct: 65 ATLKYNVAIKCATITPDEARVKEFNLKQMWRSPNGTIRNILNGTVFREPIICKNIPRLVS 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENI-DLKVYEFPKSGGIAMA 181
W KPI IGRHAFGDQYRATD IK GKL+L F+ G E I +L+VY F +GGIA++
Sbjct: 125 GWTKPICIGRHAFGDQYRATDTVIKGPGKLKLVFAP-SGNEGIKELEVYNFTGAGGIALS 183
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI+ FA+AS A ++K PL+ +TKNTILK YD +FK IF +FD ++ KF+A
Sbjct: 184 MYNTDESIRAFAEASMNFAYQKKWPLYLSTKNTILKKYDGRFKDIFQEVFDTQWNHKFKA 243
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVA LKS GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGK
Sbjct: 244 AGIWYEHRLIDDMVAYALKSDGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGK 303
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAW+R + R KLD ++ F LE
Sbjct: 304 TIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSRGLAHRPKLDGNARLLDFTEKLEA 363
Query: 362 ATLDTVQVGGKMTKDLALMLG--KTNRSSYVTTEEFIDEVAKRLQNMMLSSNE 412
A + TV++ GKMTKDLAL++ K +RS Y+ TEEFID VA+ L+ + S ++
Sbjct: 364 ACIGTVEL-GKMTKDLALLVHGPKVSRSQYLNTEEFIDAVAEELRTRLSSQSK 415
>gi|17987074|ref|NP_539708.1| (NC_003317) ISOCITRATE DEHYDROGENASE (NADP) [Brucella melitensis]
gi|17982732|gb|AAL51972.1| (AE009520) ISOCITRATE DEHYDROGENASE (NADP) [Brucella melitensis]
Length = 404
Score = 535 bits (1378), Expect = e-151
Identities = 260/407 (63%), Positives = 322/407 (78%), Gaps = 5/407 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGDE TR+IW+ IK+KLI PYLD+DLKYYDLS++ RD TNDQVT D+
Sbjct: 1 MAKIKVANPVVELDGDEMTRIIWQFIKDKLIHPYLDIDLKYYDLSVENRDATNDQVTIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A +YGV VKCATITPDEAR++EF LK+MWKSPNGTIRNILGG +FREPII +PRL
Sbjct: 61 ANAIKEYGVGVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGVIFREPIICKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W +PII+GRHAFGDQYRATD K G L ++F +DG + I+ +VY+ P S G+AM
Sbjct: 121 VPGWTQPIIVGRHAFGDQYRATDFKFPGKGTLTIKFVGEDG-QTIEHEVYQAP-SAGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+N ++SI+ FA+ASF L+R P++ +TKNTILK YD +FK IF +FD E+K KF+
Sbjct: 179 AMYNLDESIREFARASFNYGLQRGYPVYLSTKNTILKAYDGRFKDIFQEVFDAEFKSKFE 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
KI YEHRLIDDMVA LK GG++ A KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 239 EKKIWYEHRLIDDMVASALKWSGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+GEETSTNSIASIFAWTR + R KLDN D+ KF LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQHQKGEETSTNSIASIFAWTRGLAHRAKLDNNADLKKFAETLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
K +DTV+ G MTKDLAL++G +++T F+D++ + LQ M
Sbjct: 359 KVCVDTVE-SGFMTKDLALLIGPDQ--PWLSTTGFLDKIDENLQKAM 402
>gi|2497259|sp|Q40345|IDHP_MEDSA ISOCITRATE DEHYDROGENASE [NADP], CHLOROPLAST PRECURSOR
(OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC
ICDH) (IDP)
gi|7488742|pir||T09619 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) precursor - alfalfa
(fragment)
gi|166386|gb|AAA32656.1| (M93672) isocitrate dehydrogenase [Medicago sativa]
Length = 433
Score = 533 bits (1374), Expect = e-151
Identities = 259/404 (64%), Positives = 316/404 (78%), Gaps = 3/404 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TR+IWK IK+KLI P++++D+KY+DL + RD TND+VT +S+
Sbjct: 26 KIKVANPIVEMDGDEMTRIIWKYIKDKLIFPFVELDIKYFDLGLPYRDETNDKVTVESAE 85
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDEAR+KEF LK MW+SPNGTIRNIL GTVFREPII IPRL+P
Sbjct: 86 ATLKYNVAIKCATITPDEARVKEFGLKSMWRSPNGTIRNILNGTVFREPIICKNIPRLIP 145
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD IK GKL+L F + E DL+VY F GG+A+AM
Sbjct: 146 GWTKPICIGRHAFGDQYRATDSVIKGPGKLKLVFVPEGQGETTDLEVYNFTGEGGVALAM 205
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+ FA+AS +AL++K PL+ +TKNTILK YD +FK IF +++ +K K++A
Sbjct: 206 YNTDESIRSFAEASMAVALEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEAGWKSKYEAA 265
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 266 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 325
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRHFR HQ+G ETSTNSIASIFAWTR + R KLD+ ++ F LE A
Sbjct: 326 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNATLLDFTEKLEAA 385
Query: 363 TLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRLQ 404
+ V+ GKMTKDLAL+L K +R Y+ TEEFID VA L+
Sbjct: 386 CIGVVE-SGKMTKDLALILHGSKLSREHYLNTEEFIDAVAAELK 428
>gi|5007084|gb|AAD37809.1|AF155333_1 (AF155333) NADP-specific isocitrate dehydrogenase [Oryza sativa]
Length = 412
Score = 533 bits (1373), Expect = e-150
Identities = 260/411 (63%), Positives = 324/411 (78%), Gaps = 6/411 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TR+ W+ IK+KLI P+LD+D+KYYDL + RD T+D+VT +++
Sbjct: 5 KIKVANPIVEMDGDEMTRIFWQSIKDKLIFPFLDLDIKYYDLGVLHRDATDDKVTVEAAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDEAR+KEFNLK+MWKSPNGTIRNI+ GTVFREPII +PRLVP
Sbjct: 65 ATLKYNVAIKCATITPDEARVKEFNLKQMWKSPNGTIRNIINGTVFREPIICKNVPRLVP 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD +K GKL+L F D E IDL+V+ F +GG+A++M
Sbjct: 125 GWTKPICIGRHAFGDQYRATDAVLKGPGKLKLVFEGKD--EQIDLEVFNFTGAGGVALSM 182
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+ FA+AS A ++K PL+ +TKNTILK YD +FK IF +++ +K KF+A
Sbjct: 183 YNTDESIRAFAEASMTTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEAGWKSKFEAA 242
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 243 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 302
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRHFR HQ+G ETSTNSIASIFAWTR + R KLD+ ++ F LE A
Sbjct: 303 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLDFALKLEAA 362
Query: 363 TLDTVQVGGKMTKDLALML-GKTN--RSSYVTTEEFIDEVAKRLQNMMLSS 410
+ TV+ GKMTKDLAL++ G +N RS Y+ TEEFID VA L++ + ++
Sbjct: 363 CVGTVE-SGKMTKDLALLIHGSSNVTRSHYLNTEEFIDAVAAELRSRLAAN 412
>gi|169989|gb|AAA33978.1| (L12157) NADPH-specific isocitrate dehydrogenase [Glycine max]
Length = 441
Score = 531 bits (1368), Expect = e-150
Identities = 260/403 (64%), Positives = 314/403 (77%), Gaps = 3/403 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TRVIWK IK+KLILP+L++D+KYYDL + RD T+D+VT +S+
Sbjct: 34 KIKVANPIVEMDGDEMTRVIWKSIKDKLILPFLELDIKYYDLGLPYRDETDDKVTIESAE 93
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDEAR+KEF LK MWKSPNGTIRNIL GTVFREPI+ IPRLVP
Sbjct: 94 ATLKYNVAIKCATITPDEARVKEFGLKSMWKSPNGTIRNILNGTVFREPILCKNIPRLVP 153
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W K I IGRHAFGDQYRATD IK AGKL+L F + E + +V+ F GG+++AM
Sbjct: 154 GWTKAICIGRHAFGDQYRATDTVIKGAGKLKLVFVPEGQGEETEFEVFNFTGEGGVSLAM 213
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+ FA+AS AL++K PL+ +TKNTILK YD +FK IF +++ +K KF+A
Sbjct: 214 YNTDESIRSFAEASMATALEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKFEAA 273
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 274 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 333
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRHFR HQ+G ETSTNSIASIFAWTR + R KLD+ ++ F LE A
Sbjct: 334 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNAKLLDFTEKLEAA 393
Query: 363 TLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRL 403
+ V+ GKMTKDLAL+L K +R Y+ TEEFID VA L
Sbjct: 394 CIGVVE-AGKMTKDLALILHGSKLSREHYLNTEEFIDAVAAEL 435
>gi|479386|pir||S33612 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) - soybean
Length = 451
Score = 531 bits (1367), Expect = e-150
Identities = 260/403 (64%), Positives = 314/403 (77%), Gaps = 3/403 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TRVIWK IK+KLILP+L++D+KYYDL + RD T+D+VT +S+
Sbjct: 44 KIKVANPIVEMDGDEMTRVIWKSIKDKLILPFLELDIKYYDLGLPYRDETDDKVTIESAE 103
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDEAR+KEF LK MWKSPNGTIRNIL GTVFREPI+ IPRLVP
Sbjct: 104 ATLKYNVAIKCATITPDEARVKEFGLKSMWKSPNGTIRNILNGTVFREPILCKNIPRLVP 163
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W K I IGRHAFGDQYRATD IK AGKL+L F + E + +V+ F GG+++AM
Sbjct: 164 GWTKAICIGRHAFGDQYRATDTVIKGAGKLKLVFVPEGQGEETEFEVFNFTGEGGVSLAM 223
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+ FA+AS AL++K PL+ +TKNTILK YD +FK IF +++ +K KF+A
Sbjct: 224 YNTDESIRSFAEASMATALEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKFEAA 283
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 284 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 343
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRHFR HQ+G ETSTNSIASIFAWTR + R KLD+ ++ F LE A
Sbjct: 344 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNAKLLDFTEKLEAA 403
Query: 363 TLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRL 403
+ V+ GKMTKDLAL+L K +R Y+ TEEFID VA L
Sbjct: 404 CIGVVE-AGKMTKDLALILHGSKLSREHYLNTEEFIDAVAAEL 445
>gi|16126761|ref|NP_421325.1| (NC_002696) isocitrate dehydrogenase, NADP-dependent [Caulobacter
crescentus]
gi|13424081|gb|AAK24493.1| (AE005920) isocitrate dehydrogenase, NADP-dependent [Caulobacter
crescentus] [Caulobacter vibrioides]
Length = 403
Score = 529 bits (1363), Expect = e-149
Identities = 256/407 (62%), Positives = 322/407 (78%), Gaps = 5/407 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+V+MDGDE TR+IWKLIK+KLI PYLD++L YYDLS++ RD T+DQVT D+
Sbjct: 1 MAKIKVANPVVDMDGDEMTRIIWKLIKDKLIFPYLDLELDYYDLSVENRDATDDQVTIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ AT K+GVAVKCATITPDE R++EF LK+MWKSPNGTIRNILGG +FREPII +PRL
Sbjct: 61 ANATKKHGVAVKCATITPDEQRVEEFKLKKMWKSPNGTIRNILGGVIFREPIICQNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W +PII+GRHAFGDQYRATD K G L ++F +DG + I+ +V++ P + G+AM
Sbjct: 121 VPGWTQPIIVGRHAFGDQYRATDFKFPGKGTLSIKFVGEDG-QTIEHEVFKAPDA-GVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+N ++SI+ FA ASF L R P++ +TKNTILK YD +FK IF ++D EY EKF+
Sbjct: 179 AMYNLDESIRDFAHASFAYGLNRGYPVYLSTKNTILKAYDGRFKDIFQEIYDAEYAEKFK 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVA LK GG++ A KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 239 AAGIHYEHRLIDDMVASALKWSGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+GE TSTNSIASIFAWTR + R KLD+ D+ F LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQHQKGESTSTNSIASIFAWTRGLAHRAKLDDNQDLANFAATLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
K +DTV+ G MTKDLAL++G ++ ++TTE F+D++ + L+ M
Sbjct: 359 KVCIDTVE-SGYMTKDLALLVG--DKQGWLTTEGFLDKIDENLKKAM 402
>gi|417178|sp|Q04467|IDHP_BOVIN ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL PRECURSOR
(OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC
ICDH) (IDP) (ICD-M)
gi|479431|pir||S33859 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) precursor,
mitochondrial - bovine
gi|430|emb|CAA49207.1| (X69432) isocitrate dehydrogenase (NADP+) [Bos taurus]
Length = 452
Score = 528 bits (1360), Expect = e-149
Identities = 254/409 (62%), Positives = 314/409 (76%), Gaps = 6/409 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD + +AG ++ F+ DG + +VY FP +GG+ M M
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFP-AGGVGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +F+K YK +F
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDKH 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 TLDTVQVGGKMTKDLA-LMLGKTN---RSSYVTTEEFIDEVAKRLQNMM 407
++TV+ G MTKDLA + G +N ++ T +F+D + L +
Sbjct: 402 CVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRAL 449
>gi|1708401|sp|Q06197|IDHC_SOYBN ISOCITRATE DEHYDROGENASE [NADP] (OXALOSUCCINATE DECARBOXYLASE)
(IDH) (NADP+-SPECIFIC ICDH) (IDP)
Length = 413
Score = 528 bits (1360), Expect = e-149
Identities = 260/403 (64%), Positives = 314/403 (77%), Gaps = 3/403 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TRVIWK IK+KLILP+L++D+KYYDL + RD T+D+VT +S+
Sbjct: 6 KIKVANPIVEMDGDEMTRVIWKSIKDKLILPFLELDIKYYDLGLPYRDETDDKVTIESAE 65
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDEAR+KEF LK MWKSPNGTIRNIL GTVFREPI+ IPRLVP
Sbjct: 66 ATLKYNVAIKCATITPDEARVKEFGLKSMWKSPNGTIRNILNGTVFREPILCKNIPRLVP 125
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W K I IGRHAFGDQYRATD IK AGKL+L F + E + +V+ F GG+++AM
Sbjct: 126 GWTKAICIGRHAFGDQYRATDTVIKGAGKLKLVFVPEGQGEETEFEVFNFTGEGGVSLAM 185
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+ FA+AS AL++K PL+ +TKNTILK YD +FK IF +++ +K KF+A
Sbjct: 186 YNTDESIRSFAEASMATALEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKFEAA 245
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 246 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 305
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRHFR HQ+G ETSTNSIASIFAWTR + R KLD+ ++ F LE A
Sbjct: 306 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNAKLLDFTEKLEAA 365
Query: 363 TLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRL 403
+ V+ GKMTKDLAL+L K +R Y+ TEEFID VA L
Sbjct: 366 CIGVVE-AGKMTKDLALILHGSKLSREHYLNTEEFIDAVAAEL 407
>gi|1750380|gb|AAB39248.1| (U80912) NADP-isocitrate dehydrogenase [Eucalyptus globulus]
Length = 416
Score = 528 bits (1360), Expect = e-149
Identities = 258/404 (63%), Positives = 315/404 (77%), Gaps = 3/404 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TRV WK IK+KLI P+L++D+KY+DL + RD T+D+VT +S+
Sbjct: 5 KIKVENPIVEMDGDEMTRVFWKSIKDKLIFPFLELDIKYFDLGLPHRDATDDKVTIESAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDEARMKEF LK+MWKSPNGTIRNIL GTVFREPI+ IPRLVP
Sbjct: 65 ATLKYNVAIKCATITPDEARMKEFTLKQMWKSPNGTIRNILNGTVFREPIMCKNIPRLVP 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQY+ATD IK AGKL+L F + E +L+VY F +GG+A++M
Sbjct: 125 GWSKPICIGRHAFGDQYKATDTVIKGAGKLKLVFVPEGTDEKTELEVYNFTGAGGVALSM 184
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+ FA+AS A ++K PL+ +TKNTILK YD +FK IF +++ +K KF+A
Sbjct: 185 YNTDESIRSFAEASMNTAYQKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKSKFEAA 244
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 245 GIWYEHRLIDDMVAYALKSDGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 304
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAW+R + R KLDN ++ F LE A
Sbjct: 305 IEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSRGLAHRAKLDNNAKLLDFAEKLEAA 364
Query: 363 TLDTVQVGGKMTKDLALMLG--KTNRSSYVTTEEFIDEVAKRLQ 404
+ TV+ GKMTKDLAL++ K R Y+ TEEFID VA L+
Sbjct: 365 CIGTVE-SGKMTKDLALLIHGPKFTRDQYLNTEEFIDAVAVELK 407
>gi|12003362|gb|AAG43538.1|AF212319_1 (AF212319) NADP+-specific isocitrate dehydrogenase [Mus musculus]
Length = 452
Score = 527 bits (1358), Expect = e-149
Identities = 255/409 (62%), Positives = 312/409 (75%), Gaps = 6/409 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 43 RIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD + +AG +L F+ DG + +VY FP +GG+ M M
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFP-AGGVGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ ++++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 222 YNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDRN 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 TLDTVQVGGKMTKDLA-LMLGKTN---RSSYVTTEEFIDEVAKRLQNMM 407
+ TV+ G MTKDLA + G +N ++ T +F+D + L +
Sbjct: 402 CVQTVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRAL 449
>gi|7431242|pir||T07402 probable isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) ICDH-1,
cytosol - potato (fragment)
gi|940877|emb|CAA53300.1| (X75638) isocitrate dehydrogenase (NADP+) [Solanum tuberosum]
Length = 438
Score = 526 bits (1354), Expect = e-148
Identities = 253/411 (61%), Positives = 317/411 (76%), Gaps = 4/411 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KI V +PIVEMDGDE TRVIWK IK+KLILP+L++D+KY+ L + RD T+D+VT +S+
Sbjct: 27 KITVQNPIVEMDGDEMTRVIWKSIKDKLILPFLELDIKYFSLGLPHRDATDDKVTVESAE 86
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VA+KCATITPDEAR+KEFNLK MW+SPNGTIRNIL GTVFREPI+ IPRLVP
Sbjct: 87 ATQKYNVAIKCATITPDEARVKEFNLKSMWRSPNGTIRNILNGTVFREPIMCKNIPRLVP 146
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD IK AGKL+L F + E + +VY F +GG+A++M
Sbjct: 147 GWTKPICIGRHAFGDQYRATDTVIKGAGKLKLVFVPEGSDEKTEFEVYNFTGAGGVALSM 206
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++S++ FA+AS +A ++K PL+ +TKNTILK YD +FK IF +++ +K K++
Sbjct: 207 YNTDESVRSFAEASMNMAFQKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKSKYEEA 266
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 267 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 326
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAWTR + R LDN + ++ F LE A
Sbjct: 327 IEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFTEKLEAA 386
Query: 363 TLDTVQVGGKMTKDLALML---GKTNRSSYVTTEEFIDEVAKRLQNMMLSS 410
+ V+ GKMTKDLAL++ K +R Y+ TEEFID VA L+ +L +
Sbjct: 387 CIGAVE-SGKMTKDLALIIIHGSKLSREHYLNTEEFIDAVADELKARLLKA 436
>gi|4504575|ref|NP_002159.1| 
(NM_002168) isocitrate dehydrogenase 2 (NADP+), mitochondrial;
Isocitrate dehydrogenase, mitochondrial [Homo sapiens]
gi|1352423|sp|P48735|IDHP_HUMAN Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP+-specific
ICDH) (IDP) (ICD-M)
gi|1362844|pir||S57499 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) precursor,
mitochondrial - human
gi|872121|emb|CAA49208.1| (X69433) isocitrate dehydrogenase (NADP+) [Homo sapiens]
Length = 452
Score = 525 bits (1352), Expect = e-148
Identities = 253/409 (61%), Positives = 313/409 (75%), Gaps = 6/409 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++D+ LKY+DL + RD+T+DQVT DS+
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD +AG ++ F+ DG + +VY FP +GG+ M M
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F +LEK
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKV 401
Query: 363 TLDTVQVGGKMTKDLA-LMLGKTN---RSSYVTTEEFIDEVAKRLQNMM 407
++TV+ G MTKDLA + G +N ++ T +F+D + L +
Sbjct: 402 CVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTMDFLDTIKSNLDRAL 449
>gi|5007086|gb|AAD37810.1|AF155334_1 (AF155334) NADP-specific isocitrate dehydrogenase [Oryza sativa]
Length = 412
Score = 525 bits (1352), Expect = e-148
Identities = 258/412 (62%), Positives = 324/412 (78%), Gaps = 6/412 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +PIVEMDGDE TRV WK IK+KLI P+L++D+KY+DL + RD+T+D+VT +++
Sbjct: 4 TKIKVANPIVEMDGDEMTRVFWKSIKDKLIFPFLELDIKYFDLGLPYRDQTDDKVTVEAA 63
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
ATLKY VA+KCATITPDEAR+KEF+LK MWKSPNGTIRNIL GTVFREPII IPRLV
Sbjct: 64 EATLKYNVAIKCATITPDEARVKEFSLKSMWKSPNGTIRNILNGTVFREPIICKNIPRLV 123
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHAFGDQYRATD IK GKL+L + D E I+L+V+ F +GG+A +
Sbjct: 124 PGWTKPICIGRHAFGDQYRATDAVIKGPGKLKLVYEGKD--EEIELEVFNFTGAGGVAQS 181
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI+ FA+AS A ++K PL+ +TKNTILK YD +FK IF +++ ++K KF+A
Sbjct: 182 MYNTDESIRSFAEASMATAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEAQWKSKFEA 241
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGK
Sbjct: 242 AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGK 301
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAWTR + R KLD+ ++ F LE
Sbjct: 302 TIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNARLLDFTQKLEA 361
Query: 362 ATLDTVQVGGKMTKDLALML-GKTN--RSSYVTTEEFIDEVAKRLQNMMLSS 410
A + V+ GKMTKDLAL++ G +N RS Y+ TEEFID VA L++ + ++
Sbjct: 362 ACIGAVE-SGKMTKDLALLVHGSSNVTRSHYLNTEEFIDAVADELRSRLAAN 412
>gi|1708409|sp|P50215|IDH_SPHYA ISOCITRATE DEHYDROGENASE [NADP] (OXALOSUCCINATE DECARBOXYLASE)
(IDH) (NADP+-SPECIFIC ICDH) (IDP)
gi|2117471|pir||JC4600 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) - Sphingomonas
yanoikuyae
gi|1052977|gb|AAC43640.1| (U37523) isocitrate dehydrogenase [Sphingobium yanoikuyae]
Length = 406
Score = 525 bits (1351), Expect = e-148
Identities = 250/407 (61%), Positives = 323/407 (78%), Gaps = 5/407 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGDE TR+IW+ I+E+LILPYLDVDLKYYDLS+++RD T+DQ+T D+
Sbjct: 1 MAKIKVKNPVVEIDGDEMTRIIWEWIRERLILPYLDVDLKYYDLSVEKRDETSDQITIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A +YGV VKCATITPDEAR++EF LK+MWKSPNGTIRNILGG VFREPI+I +PRL
Sbjct: 61 ANAIKEYGVGVKCATITPDEARVEEFGLKKMWKSPNGTIRNILGGVVFREPIVIKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W PI++GRHAFGDQY+ATD K+ AG L +++ +G+E ++ +V+EFP S G+AM
Sbjct: 121 VPGWTDPIVVGRHAFGDQYKATDFKVPGAGTLTMKWVGTNGEE-LEYEVFEFP-SAGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N ++SI+ FAKASF L R P++ +TKNTILK YD +FK +F +FD E+ +KF+
Sbjct: 179 GMYNLDESIRDFAKASFNYGLNRGWPVYLSTKNTILKAYDGRFKDLFQEVFDAEFADKFK 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVA LK G F+ A KNYDGDVQSD VAQGFGSLGLMTS+L++PDG
Sbjct: 239 AAGIVYEHRLIDDMVASALKWSGKFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLSPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+G+ TSTN IASIFAWT+ + RGK D+T DV+KF LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQHQQGKATSTNPIASIFAWTQGLSFRGKFDDTPDVVKFAETLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
+ + TV+ GG MTKDLAL++G +++TTE+F + + L+ M
Sbjct: 359 QVCIKTVE-GGAMTKDLALLIGPDQ--AWMTTEQFFEAIRVNLEAEM 402
>gi|15982950|gb|AAL11503.1|AF367443_1 (AF367443) NADP-dependent isocitrate dehydrogenase [Prunus persica]
Length = 414
Score = 525 bits (1351), Expect = e-148
Identities = 255/404 (63%), Positives = 317/404 (78%), Gaps = 3/404 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TRV WK IK+KLILP+L++D+KY+DL + RD T+D+VT +S+
Sbjct: 5 KIKVANPIVEMDGDEMTRVFWKSIKDKLILPFLELDIKYFDLGLPHRDATDDKVTVESAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDE R+KEFNLK MW+SPNGTIRNIL GTVFREPI+ IPRL+P
Sbjct: 65 ATLKYNVAIKCATITPDEGRVKEFNLKSMWRSPNGTIRNILNGTVFREPILCKNIPRLIP 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD IK GKL+L F D E +L+VY F GG+A+AM
Sbjct: 125 GWTKPICIGRHAFGDQYRATDAVIKGPGKLKLVFVPDGKDEKTELEVYNFTGEGGVALAM 184
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+ FA+AS A ++K PL+ +TKNTILK YD +FK IF +++ ++K +++A
Sbjct: 185 YNTDESIRAFAEASMTTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEAKWKSQYEAA 244
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 245 GIWYEHRLIDDMVAYALKSDGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 304
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAWTR + R KLD+ ++ F LE+A
Sbjct: 305 IEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNAKLLDFTQKLEEA 364
Query: 363 TLDTVQVGGKMTKDLALMLG--KTNRSSYVTTEEFIDEVAKRLQ 404
+ TV+ GKMTKDLAL++ K R+ Y+ TEEFI+ VA+ L+
Sbjct: 365 CIGTVE-SGKMTKDLALIIHGPKLARNHYLNTEEFIEAVAEELR 407
>gi|14328062|gb|AAH09244.1|AAH09244 (BC009244) isocitrate dehydrogenase 2 (NADP+), mitochondrial [Homo
sapiens]
Length = 452
Score = 525 bits (1351), Expect = e-148
Identities = 253/409 (61%), Positives = 313/409 (75%), Gaps = 6/409 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++D+ LKY+DL + RD+T+DQVT DS+
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD +AG ++ F+ DG + +VY FP +GG+ M M
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F +LEK
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKV 401
Query: 363 TLDTVQVGGKMTKDLA-LMLGKTN---RSSYVTTEEFIDEVAKRLQNMM 407
++TV+ G MTKDLA + G +N ++ T +F+D + L +
Sbjct: 402 CVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRAL 449
>gi|462384|sp|P33198|IDHP_PIG ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL PRECURSOR
(OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC
ICDH) (IDP) (ICD-M)
gi|284570|pir||A43294 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42), mitochondrial - pig
gi|294223|gb|AAA31089.1| (M86719) NADPH-specific isocitrate dehydrogenase [Sus scrofa]
Length = 421
Score = 525 bits (1351), Expect = e-148
Identities = 254/409 (62%), Positives = 312/409 (76%), Gaps = 6/409 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 12 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 71
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 72 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 131
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD + +AG ++ F+ DG +VY FP +GG+ M M
Sbjct: 132 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKIVFTPKDGSSAKQWEVYNFP-AGGVGMGM 190
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +F+K YK F
Sbjct: 191 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKY 250
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 251 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 310
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 311 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 370
Query: 363 TLDTVQVGGKMTKDLA-LMLGKTN---RSSYVTTEEFIDEVAKRLQNMM 407
++TV+ G MTKDLA + G +N ++ T +F+D + L +
Sbjct: 371 CVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRAL 418
>gi|3811009|dbj|BAA34113.1| (AB019328) NADP specific isocitrate dehydrogenase [Daucus carota]
Length = 416
Score = 524 bits (1350), Expect = e-148
Identities = 253/409 (61%), Positives = 320/409 (77%), Gaps = 3/409 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M KIKV++PIVEMDGDE TRV WK IKEKLI P+LD+D+KY+DL + RD T+D+VT +S
Sbjct: 3 MQKIKVLNPIVEMDGDEMTRVFWKSIKEKLIFPFLDLDIKYFDLGLPNRDATDDRVTIES 62
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ ATLKY VA+KCATITPDE R+KEFNLK+MWKSPNGTIRNIL GTVFREPII IPRL
Sbjct: 63 AEATLKYNVAIKCATITPDETRLKEFNLKQMWKSPNGTIRNILNGTVFREPIICKNIPRL 122
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPI IGRHAFGDQYRATD+ ++ GKL++ F D E +L+V+ F +GG+A+
Sbjct: 123 VQGWNKPICIGRHAFGDQYRATDLVVQGPGKLKMVFVPDGQSEKTELEVFNFTGAGGVAL 182
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
+M+NT++SI FA+AS A +++ PL+ +TKNTILK YD +FK IF +++KE+K KF+
Sbjct: 183 SMYNTDESIHAFAEASMNTAYQKRWPLYLSTKNTILKKYDGRFKDIFQEVYEKEWKSKFE 242
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
++ I YEHRLIDDMVA LKS GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDG
Sbjct: 243 SVGIWYEHRLIDDMVAYALKSDGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDG 302
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAW+R + R KLD+ ++ F LE
Sbjct: 303 KTIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSRGLAHRAKLDDNALLLDFTEKLE 362
Query: 361 KATLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRLQNMM 407
A + TV+ GKMTKDLA++L + ++ Y+ TE FID VA L++ +
Sbjct: 363 AACIGTVE-RGKMTKDLAILLYGSRVTKAHYLNTEGFIDAVAAELRSRL 410
>gi|1708400|sp|P50217|IDHC_SOLTU ISOCITRATE DEHYDROGENASE [NADP] (OXALOSUCCINATE DECARBOXYLASE)
(IDH) (NADP+-SPECIFIC ICDH) (IDP)
gi|629723|pir||S47013 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) - potato
gi|1096518|prf||2111437A isocitrate dehydrogenase [Solanum tuberosum]
Length = 416
Score = 523 bits (1346), Expect = e-147
Identities = 253/411 (61%), Positives = 317/411 (76%), Gaps = 4/411 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KI V +PIVEMDGDE TRVIWK IK+KLILP+L++D+KY+ L + RD T+D+VT +S+
Sbjct: 5 KITVQNPIVEMDGDEMTRVIWKSIKDKLILPFLELDIKYFSLGLPHRDATDDKVTVESAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VA+KCATITPDEAR+KEFNLK MW+SPNGTIRNIL GTVFREPI+ IPRLVP
Sbjct: 65 ATQKYNVAIKCATITPDEARVKEFNLKSMWRSPNGTIRNILNGTVFREPIMCKNIPRLVP 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD IK AGKL+L F + E + +VY F +GG+A++M
Sbjct: 125 GWTKPICIGRHAFGDQYRATDTVIKGAGKLKLVFVPEGSDEKTEFEVYNFTGAGGVALSM 184
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++S++ FA+AS +A ++K PL+ +TKNTILK YD +FK IF +++ +K K++
Sbjct: 185 YNTDESVRSFAEASMNMAFQKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKSKYEEA 244
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 245 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 304
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAWTR + R LDN + ++ F LE A
Sbjct: 305 IEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFTEKLEAA 364
Query: 363 TLDTVQVGGKMTKDLALML---GKTNRSSYVTTEEFIDEVAKRLQNMMLSS 410
+ V+ GKMTKDLAL++ K +R Y+ TEEFID VA L+ +L +
Sbjct: 365 CIGAVE-SGKMTKDLALIIIHGSKLSREHYLNTEEFIDAVADELKARLLKA 414
>gi|15241443|ref|NP_196963.1| (NM_121463) isocitrate dehydrogenase - like protein [Arabidopsis
thaliana]
gi|11251314|pir||T48632 isocitrate dehydrogenase-like protein - Arabidopsis thaliana
gi|7573308|emb|CAB87626.1| (AL163792) isocitrate dehydrogenase-like protein [Arabidopsis
thaliana]
Length = 465
Score = 523 bits (1346), Expect = e-147
Identities = 255/404 (63%), Positives = 321/404 (79%), Gaps = 6/404 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+I+V +PIVEMDGDE TRVIW +IKEKLILPYLD+D+KY+DL I RD T+D+VT +S+
Sbjct: 57 RIQVQNPIVEMDGDEMTRVIWSMIKEKLILPYLDLDIKYFDLGILNRDATDDKVTVESAE 116
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A LKY VA+KCATITPDE R+KEF LK MW+SPNGTIRNIL GTVFREPI+ IPRLVP
Sbjct: 117 AALKYNVAIKCATITPDEGRVKEFGLKSMWRSPNGTIRNILDGTVFREPIMCSNIPRLVP 176
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
WEKPI IGRHAFGDQYRATD IK GKL++ F +DG ++L VY+F K G+A+AM
Sbjct: 177 GWEKPICIGRHAFGDQYRATDTVIKGPGKLKMVF--EDGNAPVELDVYDF-KGPGVALAM 233
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+N ++SI+ FA++S +AL +K PL+ +TKNTILK YD +FK IF +++ +K+KF+
Sbjct: 234 YNVDESIRAFAESSMAMALTKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKQKFEEH 293
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA +KS+GG++ A KNYDGDVQSD++AQGFGSLGLMTS+L++ DGKT
Sbjct: 294 SIWYEHRLIDDMVAYAVKSEGGYVWACKNYDGDVQSDLLAQGFGSLGLMTSVLLSADGKT 353
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
ESEAAHGTVTRHFR HQ+G+ETSTNSIASIFAWTR + R KLD + ++ F LE +
Sbjct: 354 LESEAAHGTVTRHFRLHQKGQETSTNSIASIFAWTRGLEHRAKLDKNEKLMDFVKKLESS 413
Query: 363 TLDTVQVGGKMTKDLALMLG--KTNRSSYVTTEEFIDEVAKRLQ 404
++TV+ GKMTKDLAL++ K +R ++ TEEFID VA +L+
Sbjct: 414 CVNTVET-GKMTKDLALLIHGPKVSRDLFLNTEEFIDAVASKLK 456
>gi|5764653|gb|AAD51361.1|AF176669_1 (AF176669) NADP-isocitrate dehydrogenase [Citrus limon]
Length = 414
Score = 522 bits (1345), Expect = e-147
Identities = 254/404 (62%), Positives = 315/404 (77%), Gaps = 3/404 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TRV WK IK+KLI P+L++D+KY+DL + RD T+D+VT +S+
Sbjct: 5 KIKVANPIVEMDGDEMTRVFWKSIKDKLIFPFLELDIKYFDLGLPNRDATDDKVTVESAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDEAR+KEF LK+MWKSPNGTIRNIL GTVFREPII +PRL+P
Sbjct: 65 ATLKYNVAIKCATITPDEARVKEFVLKQMWKSPNGTIRNILNGTVFREPIICKNVPRLIP 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD I+ GKL+L F + E +L+VY F GG+A++M
Sbjct: 125 GWTKPICIGRHAFGDQYRATDTVIQGPGKLKLVFVPEGKDEKTELEVYNFTGEGGVALSM 184
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+ FA+AS A ++K PL+ +TKNTILKNYD +FK IF +++ +K KF+A
Sbjct: 185 YNTDESIRSFAEASMNTAYQKKWPLYLSTKNTILKNYDGKFKDIFQEVYEANWKSKFEAA 244
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS+GG++ A K+YDG+VQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 245 GIWYEHRLIDDMVAYALKSEGGYVWACKDYDGNVQSDFLAQGFGSLGLMTSVLVCPDGKT 304
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAW+R + R KLDN ++ F LE A
Sbjct: 305 IEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSRGLAHRAKLDNNARLLDFTEKLEAA 364
Query: 363 TLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRLQ 404
+ TV+ GKMTKDLAL++ K R Y+ TEEFID VA L+
Sbjct: 365 CVGTVE-SGKMTKDLALIIHGSKMTREHYLNTEEFIDAVADDLR 407
>gi|3811007|dbj|BAA34112.1| (AB019327) NADP specific isocitrate dehydrogenase [Daucus carota]
Length = 412
Score = 522 bits (1344), Expect = e-147
Identities = 253/404 (62%), Positives = 315/404 (77%), Gaps = 3/404 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TRV WK IK+KLI P++++D+KY+DL + RD T+D+VT +S+
Sbjct: 5 KIKVANPIVEMDGDEMTRVFWKSIKDKLIFPFVELDIKYFDLGLPHRDATDDKVTVESAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDEAR+KEF LK+MWKSPNGTIRNIL GTVFREPII IP+L+P
Sbjct: 65 ATLKYNVAIKCATITPDEARVKEFGLKQMWKSPNGTIRNILNGTVFREPIICKNIPKLIP 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD I+ GKL+L F + +E +L+VY F +GG+A++M
Sbjct: 125 GWTKPICIGRHAFGDQYRATDAVIQGPGKLKLVFVPEGKEEKTELEVYNFTGAGGVALSM 184
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+ FA+AS A ++K PL+ +TKNTILK YD +FK IF +++ +K K+ A
Sbjct: 185 YNTDESIRSFAEASMATAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYDAA 244
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 245 GIWYEHRLIDDMVAYALKSDGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 304
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAW+R + R KLD+ ++ F LE A
Sbjct: 305 IEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSRGLAHRAKLDDNAALLSFAEKLEAA 364
Query: 363 TLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRLQ 404
+ TV+ GKMTKDLAL+L K +R Y+ TEEFID VA L+
Sbjct: 365 CVGTVE-SGKMTKDLALILHGSKLSREHYLNTEEFIDAVASDLK 407
>gi|2623962|emb|CAA73139.1| (Y12540) isocitrate dehydrogenase (NADP+) [Apium graveolens]
Length = 412
Score = 522 bits (1344), Expect = e-147
Identities = 252/404 (62%), Positives = 316/404 (77%), Gaps = 3/404 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TRV WK IK+KLI P++++D+KY+DL + RD T+D+VT +S+
Sbjct: 5 KIKVANPIVEMDGDEMTRVFWKSIKDKLIFPFVELDIKYFDLGLPHRDATDDKVTVESAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDEAR++EF LK+MWKSPNGTIRNIL GTVFREPII IP+L+P
Sbjct: 65 ATLKYNVAIKCATITPDEARVEEFGLKQMWKSPNGTIRNILNGTVFREPIICKNIPKLIP 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD IK GKL+L F + +E +L+VY F +GG+A++M
Sbjct: 125 GWTKPICIGRHAFGDQYRATDAVIKGPGKLKLVFVPEGKEEKTELEVYNFTGAGGVALSM 184
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+ FA+AS A ++K PL+ +TKNTILK YD +FK IF +++ +K K++A
Sbjct: 185 YNTDESIRSFAEASMTTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYEAA 244
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 245 GIWYEHRLIDDMVAYALKSDGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 304
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAW+R + R KLD+ ++ F LE A
Sbjct: 305 IEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSRGLAHRAKLDDNAALLSFAEKLEAA 364
Query: 363 TLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRLQ 404
+ TV+ G+MTKDLAL+L K +R Y+ TEEFID VA L+
Sbjct: 365 CVGTVE-AGRMTKDLALILHGSKLSREHYLNTEEFIDAVADDLK 407
>gi|15965545|ref|NP_385898.1| (NC_003047) PROBABLE ISOCITRATE DEHYDROGENASE [NADP] PROTEIN
[Sinorhizobium meliloti]
gi|15074726|emb|CAC46371.1| (AL591788) PROBABLE ISOCITRATE DEHYDROGENASE [NADP] PROTEIN
[Sinorhizobium meliloti]
Length = 404
Score = 521 bits (1343), Expect = e-147
Identities = 251/407 (61%), Positives = 320/407 (77%), Gaps = 5/407 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGDE TR+IW+ IK+KLI PYLD+DL+YYDL ++ RD T+DQVT D+
Sbjct: 1 MAKIKVANPVVELDGDEMTRIIWQFIKDKLIHPYLDLDLEYYDLGVENRDATDDQVTIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A K+GV VKCATITPDE R++EF LK+MWKSPNGTIRNILGG +FREPII +PRL
Sbjct: 61 ANAIKKHGVGVKCATITPDEGRVEEFKLKKMWKSPNGTIRNILGGVIFREPIICKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPII+GRHAFGDQYRATD K GKL ++F +DG + I+ VY+ P G+A+
Sbjct: 121 VPGWTKPIIVGRHAFGDQYRATDFKFPGKGKLSIKFVGEDG-QTIEHDVYDAP-GAGVAL 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+N ++SI FA+ASF L+RK+P++ +TKNTILK YD +FK IF +FD+E+ +F+
Sbjct: 179 AMYNLDESITEFARASFNYGLQRKVPVYLSTKNTILKAYDGRFKDIFQKVFDEEFAAQFK 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A K+ YEHRLIDDMVA LK GG++ A KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 239 AEKLWYEHRLIDDMVASALKWSGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+GEETSTNSIASIFAWTR + R KLD ++ KF LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQHQKGEETSTNSIASIFAWTRGLAHRAKLDGNAELAKFSETLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
+ +DTV+ G MTKDLAL++G +++T F+D++ + L+ M
Sbjct: 359 RVCVDTVE-SGFMTKDLALLIGPDQ--PWLSTTGFLDKIDENLRKAM 402
>gi|1708402|sp|P50218|IDHC_TOBAC ISOCITRATE DEHYDROGENASE [NADP] (OXALOSUCCINATE DECARBOXYLASE)
(IDH) (NADP+-SPECIFIC ICDH) (IDP)
gi|2129951|pir||S65065 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42), cytosolic - common
tobacco
gi|1617198|emb|CAA54912.1| (X77944) isocitrate dehydrogenase (NADP+) [Nicotiana tabacum]
Length = 415
Score = 521 bits (1342), Expect = e-147
Identities = 252/410 (61%), Positives = 317/410 (76%), Gaps = 3/410 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TRVIWK IK+KLI P+L++D+KY+DL + RD T+D+VT +S+
Sbjct: 5 KIKVENPIVEMDGDEMTRVIWKSIKDKLICPFLELDIKYFDLGLPHRDATDDKVTVESAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VA+KCATITPDEAR+KEFNLK MW+SPNGTIRNIL GTVFREPI+ IPRLVP
Sbjct: 65 ATQKYNVAIKCATITPDEARVKEFNLKSMWRSPNGTIRNILNGTVFREPIMCKNIPRLVP 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD I+ AGKL+L F + E + +VY F +GG+A++M
Sbjct: 125 GWTKPICIGRHAFGDQYRATDTVIQGAGKLKLVFVPEGTDEKTEFEVYNFTGAGGVALSM 184
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++S++ FA+AS +A ++K PL+ +TKNTILK YD +FK IF +++ +K K++
Sbjct: 185 YNTDESVRSFAEASMNMAYQKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKSKYEEA 244
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDM A LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 245 GIWYEHRLIDDMAAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 304
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAWTR + R LDN + ++ F LE A
Sbjct: 305 IEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFTEKLEAA 364
Query: 363 TLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRLQNMMLSS 410
+ V+ GKMTKDLAL++ K +R Y+ TEEFID VA L+ +L +
Sbjct: 365 CIGAVE-SGKMTKDLALIIHGSKLSRDHYLNTEEFIDAVADELKARLLKA 413
>gi|7431245|pir||T04355 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) precursor,
mitochondrial - common tobacco
gi|3021512|emb|CAA65503.1| (X96728) isocitrate dehydrogenase (NADP+) [Nicotiana tabacum]
Length = 482
Score = 521 bits (1341), Expect = e-147
Identities = 249/408 (61%), Positives = 319/408 (78%), Gaps = 4/408 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
SKI+V +PIVEMDGDE TRVIW +IKEKLI PYL++D KYYDL I RD T+DQVT +S+
Sbjct: 71 SKIRVENPIVEMDGDEMTRVIWTMIKEKLIYPYLELDTKYYDLGILNRDATDDQVTVESA 130
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
ATLKY VAVKCATITPDE R+KEF LK MW+SPN TIRNIL GTVFREPI+ +PR+V
Sbjct: 131 EATLKYNVAVKCATITPDETRVKEFGLKSMWRSPNATIRNILNGTVFREPILCKNVPRIV 190
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+KPI IGRHAFGDQYRATD I GKL++ F ++G+ +L VY+F K G+A+A
Sbjct: 191 PGWKKPICIGRHAFGDQYRATDAVINGPGKLKMVFEPENGEAPTELDVYDF-KGPGVALA 249
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+N + SI+ FA++S +A +K PL+ +TKNTILK YD +FK IF+ ++++++K++F+
Sbjct: 250 MYNVDQSIRAFAESSMSMAFSKKWPLYLSTKNTILKKYDGRFKDIFEEVYEEKWKQQFEE 309
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVA LKS GG++ A KNYDGDVQSD++AQGFGSLGLMTS+L++ DGK
Sbjct: 310 HSIWYEHRLIDDMVAYALKSGGGYVWACKNYDGDVQSDLLAQGFGSLGLMTSVLLSSDGK 369
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRHFR HQ+G+ETSTNS+ASIFAW R + R +LD + +F + LE
Sbjct: 370 TLEAEAAHGTVTRHFRLHQKGQETSTNSVASIFAWARGLGHRAQLDGNQKLSEFVHALEA 429
Query: 362 ATLDTVQVGGKMTKDLALMLG--KTNRSSYVTTEEFIDEVAKRLQNMM 407
A + T++ GKMTKDLA+++ K +R Y+ TEEFID VA++LQ +
Sbjct: 430 ACVGTIE-SGKMTKDLAILVHGPKVSREHYLNTEEFIDPVAQKLQEKL 476
>gi|7431243|pir||T04356 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) precursor,
mitochondrial - common tobacco
gi|3021513|emb|CAA65504.1| (X96728) isocitrate dehydrogenase (NADP+) [Nicotiana tabacum]
Length = 470
Score = 520 bits (1339), Expect = e-146
Identities = 249/408 (61%), Positives = 319/408 (78%), Gaps = 4/408 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
SKI+V +PIVEMDGDE TRVIW +IKEKLI PYL++D KYYDL I RD T+DQVT +S+
Sbjct: 59 SKIRVENPIVEMDGDEMTRVIWTMIKEKLIYPYLELDTKYYDLGILNRDATDDQVTVESA 118
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
ATLKY VAVKCATITPDE R+KEF LK MW+SPN TIRNIL GTVFREPI+ +PR+V
Sbjct: 119 EATLKYNVAVKCATITPDETRVKEFGLKSMWRSPNATIRNILNGTVFREPILCKNVPRIV 178
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+KPI IGRHAFGDQYRATD I GKL++ F ++G+ +L VY+F K G+A+A
Sbjct: 179 PGWKKPICIGRHAFGDQYRATDAVINGPGKLKMVFEPENGEAPTELDVYDF-KGPGVALA 237
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+N + SI+ FA++S +A +K PL+ +TKNTILK YD +FK IF+ ++++++K++F+
Sbjct: 238 MYNVDQSIRAFAESSMSMAFSKKWPLYLSTKNTILKKYDGRFKDIFEEVYEEKWKQQFEE 297
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVA LKS GG++ A KNYDGDVQSD++AQGFGSLGLMTS+L++ DGK
Sbjct: 298 HSIWYEHRLIDDMVAYALKSGGGYVWACKNYDGDVQSDLLAQGFGSLGLMTSVLLSSDGK 357
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRHFR HQ+G+ETSTNS+ASIFAW R + R +LD + +F + LE
Sbjct: 358 TLEAEAAHGTVTRHFRLHQKGQETSTNSVASIFAWARGLGHRAQLDGNQKLSEFVHALEA 417
Query: 362 ATLDTVQVGGKMTKDLALMLG--KTNRSSYVTTEEFIDEVAKRLQNMM 407
A + T++ GKMTKDLA+++ K +R Y+ TEEFID VA++LQ +
Sbjct: 418 ACVGTIE-SGKMTKDLAILVHGPKVSREHYLNTEEFIDPVAQKLQEKL 464
>gi|8133104|gb|AAF73472.1|AF268076_1 (AF268076) NADP-dependent isocitrate dehydrogenase [Sinorhizobium
meliloti]
Length = 404
Score = 519 bits (1336), Expect = e-146
Identities = 249/407 (61%), Positives = 321/407 (78%), Gaps = 5/407 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGD+ TR+IW+ IK+KLI PYLD+DL+YYDL ++ RD T+DQVT D+
Sbjct: 1 MAKIKVANPVVELDGDQMTRIIWQFIKDKLIHPYLDLDLEYYDLGVENRDATDDQVTIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A K+GV VKCATITPDE R++EF LK+MWKSPNGTIRNILGG +FREPII +PRL
Sbjct: 61 ANAIKKHGVGVKCATITPDEGRVEEFKLKKMWKSPNGTIRNILGGVIFREPIICKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPII+GRHAFGDQYRATD K GKL ++F +DG + I+ VY+ P G+A+
Sbjct: 121 VPGWTKPIIVGRHAFGDQYRATDFKFPGKGKLSIKFVGEDG-QTIEHDVYDAP-GAGVAL 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+N ++SI FA+ASF L+RK+P++ +TKNTILK YD +FK IF +F++E+ ++F+
Sbjct: 179 AMYNLDESITEFARASFNYGLQRKVPVYLSTKNTILKAYDGRFKDIFQKVFEEEFADQFK 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A K+ YEHRLIDDMVA LK GG++ A KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 239 AEKLWYEHRLIDDMVASALKWSGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+GEETSTNSIASIFAWTR + R KLD ++ KF LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQHQKGEETSTNSIASIFAWTRGLAHRAKLDGNTELAKFSETLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
+ +DTV+ G MTKDLAL++G +++T F+D++ + L+ M
Sbjct: 359 RVCVDTVE-SGFMTKDLALLIGPDQ--PWLSTTGFLDKIDENLRKAM 402
>gi|542060|pir||S42892 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) - common tobacco
Length = 415
Score = 518 bits (1335), Expect = e-146
Identities = 251/410 (61%), Positives = 316/410 (76%), Gaps = 3/410 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TRVIWK IK+KLI P+L++D+KY+DL + RD T+D+VT +S+
Sbjct: 5 KIKVENPIVEMDGDEMTRVIWKSIKDKLICPFLELDIKYFDLGLPHRDATDDKVTVESAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
T KY VA+KCATITPDEAR+KEFNLK MW+SPNGTIRNIL GTVFREPI+ IPRLVP
Sbjct: 65 RTQKYNVAIKCATITPDEARVKEFNLKSMWRSPNGTIRNILNGTVFREPIMCKNIPRLVP 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD I+ AGKL+L F + E + +VY F +GG+A++M
Sbjct: 125 GWTKPICIGRHAFGDQYRATDTVIQGAGKLKLVFVPEGTDEKTEFEVYNFTGAGGVALSM 184
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++S++ FA+AS +A ++K PL+ +TKNTILK YD +FK IF +++ +K K++
Sbjct: 185 YNTDESVRSFAEASMNMAYQKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKSKYEEA 244
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDM A LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 245 GIWYEHRLIDDMAAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 304
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAWTR + R LDN + ++ F LE A
Sbjct: 305 IEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFTEKLEAA 364
Query: 363 TLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRLQNMMLSS 410
+ V+ GKMTKDLAL++ K +R Y+ TEEFID VA L+ +L +
Sbjct: 365 CIGAVE-SGKMTKDLALIIHGSKLSRDHYLNTEEFIDAVADELKARLLKA 413
>gi|15221788|ref|NP_175836.1| (NM_104312) NADP-isocitrate dehydrogenase, putative [Arabidopsis
thaliana]
gi|4585978|gb|AAD25614.1|AC005287_16 (AC005287) NADP specific isocitrate dehydrogenase [Arabidopsis
thaliana]
gi|12744346|gb|AAK06592.1|AF316501_1 (AF316501) NADP-specific isocitrate dehydrogenase [Arabidopsis
thaliana]
Length = 416
Score = 518 bits (1333), Expect = e-146
Identities = 246/411 (59%), Positives = 319/411 (76%), Gaps = 4/411 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV++P+VEMDGDE TRVIWK IK+KLI P+L++D+KY+DL + RD T+D+VT +++
Sbjct: 5 KIKVINPVVEMDGDEMTRVIWKFIKDKLIFPFLELDIKYFDLGLPNRDFTDDKVTIETAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDEAR++EF LK+MW+SPNGTIRNIL GTVFREPII IPRLVP
Sbjct: 65 ATLKYNVAIKCATITPDEARVREFGLKKMWRSPNGTIRNILNGTVFREPIICRNIPRLVP 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD+ + + GKL+L F + + +V+ F GG+A+AM
Sbjct: 125 GWTKPICIGRHAFGDQYRATDLIVNEPGKLKLVFEPSGSSQKTEFEVFNF-TGGGVALAM 183
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+ FA++S A ++K PL+ +TKNTILK YD +FK IF +++ ++ K++A
Sbjct: 184 YNTDESIRAFAESSMYTAYQKKWPLYLSTKNTILKIYDGRFKDIFQEVYEANWRSKYEAA 243
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA +KS+GG++ A KNYDGDVQSD +AQG+GSLG+MTS+L+ PDGKT
Sbjct: 244 GIWYEHRLIDDMVAYAMKSEGGYVWACKNYDGDVQSDFLAQGYGSLGMMTSVLVCPDGKT 303
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAW+R + R KLD+ ++ + LE A
Sbjct: 304 IEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSRGLAHRAKLDSNAALLSYTEKLEAA 363
Query: 363 TLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ TV+ GKMTKDLAL++ K R YV TEEFID VA L+ +L +N
Sbjct: 364 CMGTVE-SGKMTKDLALLIHGAKVRRDQYVNTEEFIDAVAWELKRRLLGNN 413
>gi|322709|pir||S28423 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) - alfalfa
Length = 412
Score = 518 bits (1333), Expect = e-146
Identities = 254/404 (62%), Positives = 309/404 (75%), Gaps = 3/404 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TR+IWK IK+KLI P++++D+KY+DL + RD TND+VT +S+
Sbjct: 5 KIKVANPIVEMDGDEMTRIIWKYIKDKLIFPFVELDIKYFDLGLPYRDETNDKVTVESAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDEAR+KEF LK MW+SPNGTIRNIL GTVFREPII IPRL+P
Sbjct: 65 ATLKYNVAIKCATITPDEARVKEFGLKSMWRSPNGTIRNILNGTVFREPIICKNIPRLIP 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD IK GKL+L F + E DL+VY F GG+A+AM
Sbjct: 125 GWTKPICIGRHAFGDQYRATDSVIKGPGKLKLVFVPEGQGETTDLEVYNFTGEGGVALAM 184
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+ FA+AS +AL++K PL+ +TKNTILK YD +FK IF +++ +K K++A
Sbjct: 185 YNTDESIRSFAEASMAVALEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEAGWKSKYEAA 244
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 245 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 304
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGT+TRHFR HQ+G ETSTNSIASIFAWTR + F LE A
Sbjct: 305 IEAEAAHGTLTRHFRVHQKGGETSTNSIASIFAWTRGVAHSENWMTMLHSWIFTEKLEAA 364
Query: 363 TLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRLQ 404
+ V+ GKMTKDLAL+L K +R Y+ TEEFID VA L+
Sbjct: 365 CIGVVE-SGKMTKDLALILHGSKLSREHYLNTEEFIDAVAAELK 407
>gi|15889170|ref|NP_354851.1| (NC_003062) AGR_C_3429p [Agrobacterium tumefaciens] [Agrobacterium
tumefaciens str. C58 (Cereon)]
gi|17935760|ref|NP_532550.1| (NC_003304) isocitrate dehydrogenase [NADP] [Agrobacterium
tumefaciens str. C58 (U. Washington)]
gi|15156986|gb|AAK87636.1| (AE008106) AGR_C_3429p [Agrobacterium tumefaciens str. C58
(Cereon)]
gi|17740317|gb|AAL42866.1| (AE009141) isocitrate dehydrogenase [NADP] [Agrobacterium
tumefaciens str. C58 (U. Washington)]
Length = 455
Score = 517 bits (1332), Expect = e-146
Identities = 245/407 (60%), Positives = 320/407 (78%), Gaps = 5/407 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+V++DGDE TR+IW+LIK+KLILPYLD+D++YYDLS++ RD TNDQVT D+
Sbjct: 52 MAKIKVANPVVDLDGDEMTRIIWQLIKDKLILPYLDLDIEYYDLSVENRDATNDQVTVDA 111
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
++A K+GV +KCATITPDE R++EF LK+MWKSPNGTIRNILGG +FREPII +PRL
Sbjct: 112 AHAIKKHGVGIKCATITPDEQRVEEFGLKQMWKSPNGTIRNILGGVIFREPIICKNVPRL 171
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPI++GRHAFGDQY+ATD K GKL ++F +DG I+ V++ P S G+A+
Sbjct: 172 VPGWTKPIVVGRHAFGDQYKATDFKFPGKGKLTIKFVGEDGTV-IEKDVFDAP-SAGVAL 229
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+N ++SI+ FA+AS L RK P++ +TKNTILK YD +FK IF+ ++ E+K KF
Sbjct: 230 AMYNLDESIREFARASMMYGLMRKWPVYLSTKNTILKAYDGRFKDIFEEVYQTEFKAKFD 289
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
+ ITYEHRLIDDMVA LK GG++ A KNYDGDVQSD VAQGFGSLGLMTS+L++PDG
Sbjct: 290 EVGITYEHRLIDDMVASALKWSGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLSPDG 349
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
+T E+EAAHGTVTRH+R+HQ+G+ETSTNSIASIFAWTR + R KLD+ ++ KF LE
Sbjct: 350 RTVEAEAAHGTVTRHYRQHQKGQETSTNSIASIFAWTRGLAHRAKLDDNAELAKFATTLE 409
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
+DTV+ G MTKDLAL++G +++T F+D++ + L+ M
Sbjct: 410 TVCVDTVE-SGFMTKDLALLIGPDQ--PWLSTTAFLDKIDENLKTAM 453
>gi|15610475|ref|NP_217856.1| (NC_000962) icd1 [Mycobacterium tuberculosis H37Rv]
gi|15842935|ref|NP_337972.1| (NC_002755) isocitrate dehydrogenase, NADP-dependent [Mycobacterium
tuberculosis CDC1551]
gi|6225523|sp|O53389|IDH_MYCTU Isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase)
(IDH) (NADP+-specific ICDH) (IDP)
gi|7431246|pir||B70846 probable icd1 protein - Mycobacterium tuberculosis (strain H37RV)
gi|2894249|emb|CAA17111.1| (AL021841) icd1 [Mycobacterium tuberculosis H37Rv]
gi|13883270|gb|AAK47786.1| (AE007151) isocitrate dehydrogenase, NADP-dependent [Mycobacterium
tuberculosis CDC1551]
Length = 409
Score = 514 bits (1324), Expect = e-145
Identities = 244/402 (60%), Positives = 311/402 (76%), Gaps = 3/402 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV P+VE+DGDE TRVIWKLIK+ LILPYLD+ L YYDL I+ RD T+DQVT D++Y
Sbjct: 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A K+GV VKCATITPDEAR++EFNLK+MW SPNGTIRNILGGT+FREPI+I +PRLVP
Sbjct: 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI+IGRHAFGDQYRAT+ K+ + G + L F+ DG I ++ P+ GG+ + M
Sbjct: 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+N +SI+ FA+ASF L K P++ +TKNTILK YD FK F+ ++++E+K +F+A
Sbjct: 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
+TYEHRLIDDMVA LK +GG++ A KNYDGDVQSD VAQG+GSLGLMTS+L+T DGKT
Sbjct: 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R++Q G+ TSTN IASIFAWTR + RGKLD T +VI F + LE
Sbjct: 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365
Query: 363 TLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
+ TV+ GKMTKDLA+++G ++ +EEF+D +A L+
Sbjct: 366 VIATVE-SGKMTKDLAILIGP--EQDWLNSEEFLDAIADNLE 404
>gi|6680343|ref|NP_032348.1| (NM_008322) isocitrate dehydrogenase 2 (NADP+), mitochondrial [Mus
musculus]
gi|1708406|sp|P54071|IDHP_MOUSE ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL PRECURSOR
(OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC
ICDH) (IDP) (ICD-M)
gi|1236984|gb|AAC52473.1| (U51167) isocitrate dehydrogenase [Mus musculus]
Length = 523
Score = 514 bits (1323), Expect = e-145
Identities = 247/409 (60%), Positives = 305/409 (74%), Gaps = 7/409 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 115 RIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 174
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A KY +AVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREP I IPRLVP
Sbjct: 175 AAQKYSMAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPSICKNIPRLVP 234
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD + +AG +L F+ +G + +VY FP GG+ M M
Sbjct: 235 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKNGSSAKEWEVYNFP-GGGVGMGM 293
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ ++++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 294 YNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDRN 353
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+A FGSLGLMTS+L+ PDGKT
Sbjct: 354 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILASRFGSLGLMTSVLVCPDGKT 413
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TST IASIFAWTR + RGKLD D+I+F EK
Sbjct: 414 IEAEAAHGTVTRHYREHQKGRPTSTKGIASIFAWTRGLEHRGKLDGNQDLIRFAQTREKV 473
Query: 363 TLDTVQVGGKMTKDLA-LMLGKTN---RSSYVTTEEFIDEVAKRLQNMM 407
+ TV+ G MTKDLA + G +N ++ T +F+D + L +
Sbjct: 474 CVQTVE--GAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRAL 520
>gi|1589591|prf||2211361A isocitrate dehydrogenase [Mus musculus]
Length = 523
Score = 514 bits (1323), Expect = e-145
Identities = 247/409 (60%), Positives = 305/409 (74%), Gaps = 7/409 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 115 RIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 174
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A KY +AVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREP I IPRLVP
Sbjct: 175 AAQKYSMAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPSICKNIPRLVP 234
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD + +AG +L F+ +G + +VY FP GG+ M M
Sbjct: 235 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKNGSSAKEWEVYNFP-GGGVGMGM 293
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ ++++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 294 YNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDRN 353
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+A FGSLGLMTS+L+ PDGKT
Sbjct: 354 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILASRFGSLGLMTSVLVCPDGKT 413
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TST IASIFAWTR + RGKLD D+I+F EK
Sbjct: 414 IEAEAAHGTVTRHYREHQKGRPTSTKGIASIFAWTRGLEHRGKLDGNQDLIRFAQTREKV 473
Query: 363 TLDTVQVGGKMTKDLA-LMLGKTN---RSSYVTTEEFIDEVAKRLQNMM 407
+ TV+ G MTKDLA + G +N ++ T +F+D + L +
Sbjct: 474 CVQTVE--GAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRAL 520
>gi|17550822|ref|NP_509875.1| (NM_077474) Isocitrate and isopropylmalate dehydrogenases
[Caenorhabditis elegans]
gi|7497045|pir||T19733 hypothetical protein C34F6.8 - Caenorhabditis elegans
gi|3874799|emb|CAB03943.1| (Z81479) predicted using Genefinder~contains similarity to Pfam
domain: PF00180 (Isocitrate and isopropylmalate
dehydrogenases), Score=349.6, E-value=3.7e-104, N=1~cDNA
EST yk229e6.3 comes from this gene~cDNA EST yk258f7.3
comes from this gene~cDNA EST>
Length = 435
Score = 513 bits (1321), Expect = e-144
Identities = 247/409 (60%), Positives = 319/409 (77%), Gaps = 6/409 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +P+V++DGDE TR+IWK IK KLILPYLD+D+KYYDL ++ RD TNDQVT D+++
Sbjct: 26 KIKVDNPVVDLDGDEMTRIIWKEIKNKLILPYLDLDIKYYDLGLEYRDETNDQVTIDAAH 85
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A L++ V +KCATITPDEAR+KEFNLK+MW SPNGTIRNILGGTVFREPI+ IPRLVP
Sbjct: 86 AILEHSVGIKCATITPDEARIKEFNLKKMWLSPNGTIRNILGGTVFREPILCKNIPRLVP 145
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W +PI IGRHAFGDQY+ TD+ I L+L + DG +++ VY+F KSGG+ +AM
Sbjct: 146 GWTQPITIGRHAFGDQYKCTDLVIPSGSTLQLLVNKPDGSKDVH-NVYDFKKSGGVGLAM 204
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SIKGFA + F+ AL ++ PL+ +TKNTILK YD +FK IF ++++K+Y+ F+
Sbjct: 205 YNTDESIKGFAHSCFQYALMKQWPLYLSTKNTILKKYDGRFKDIFQDIYEKKYEADFKNN 264
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDD VAQ LKS GGF+ A KNYDGDVQSDIVAQG+GSLGLM+S+L+ PDGKT
Sbjct: 265 KIWYEHRLIDDQVAQALKSSGGFVWACKNYDGDVQSDIVAQGYGSLGLMSSVLMCPDGKT 324
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RG LDN + + F LEKA
Sbjct: 325 IEAEAAHGTVTRHYREHQKGNSTSTNPIASIFAWTRGLHHRGVLDNNEALKTFSLTLEKA 384
Query: 363 TLDTVQVGGKMTKDLALML----GKTNRSSYVTTEEFIDEVAKRLQNMM 407
+DTV+ GKMTKDL++ + T + +Y+ TE+F+ + ++ +M
Sbjct: 385 CIDTVE-EGKMTKDLSICIHGTKKGTEKGAYLITEDFLSAIDTKMAELM 432
>gi|15218869|ref|NP_176768.1| (NM_105265) isocitrate dehydrogenase, putative [Arabidopsis
thaliana]
gi|6227018|gb|AAF06054.1|AC009513_10 (AC009513) Strong similarity to gb|AF155333 NADP-specific
isocitrate dehydrogenase from Oryza sativa. ESTs
gb|R30474, gb|H36712, gb|T22563, gb|N97293, gb|T43729,
gb|Z17440, gb|Z34193, gb|Z46528, gb|T14072, gb|T42413,
gb|AA389759, gb|N38098, gb|T43337,>
gi|15010660|gb|AAK73989.1| (AY045631) At1g65930/F12P19_10 [Arabidopsis thaliana]
gi|16930443|gb|AAL31907.1|AF419575_1 (AF419575) At1g65930/F12P19_10 [Arabidopsis thaliana]
Length = 410
Score = 513 bits (1320), Expect = e-144
Identities = 253/407 (62%), Positives = 312/407 (76%), Gaps = 5/407 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TRVIWK IK+KLI P++++D+KY+DL + RD T+D+VT +S+
Sbjct: 5 KIKVANPIVEMDGDEMTRVIWKSIKDKLITPFVELDIKYFDLGLPHRDATDDKVTIESAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VA+KCATITPDE R+ EF LK+MW+SPNGTIRNIL GTVFREPII +P+LVP
Sbjct: 65 ATKKYNVAIKCATITPDEGRVTEFGLKQMWRSPNGTIRNILNGTVFREPIICKNVPKLVP 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD IK GKL + F DGK + +V+ F GG+AMAM
Sbjct: 125 GWTKPICIGRHAFGDQYRATDAVIKGPGKLTMTFEGKDGK--TETEVFTFTGEGGVAMAM 182
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+ FA AS A ++K PL+ +TKNTILK YD +FK IF +++ +K K+ A
Sbjct: 183 YNTDESIRAFADASMNTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEASWKSKYDAA 242
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGKT
Sbjct: 243 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKT 302
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRHFR HQ+G ETSTNSIASIFAWTR + R KLD+ ++ F LE A
Sbjct: 303 IEAEAAHGTVTRHFRVHQKGGETSTNSIASIFAWTRGLAHRAKLDDNAKLLDFTEKLEAA 362
Query: 363 TLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRLQNMM 407
+ TV+ GKMTKDLAL++ K +R +Y+ TEEFID VA L+ +
Sbjct: 363 CVGTVE-SGKMTKDLALIIHGSKLSRDTYLNTEEFIDAVAAELKERL 408
>gi|5738864|emb|CAA63220.1| (X92486) isocitrate dehydrogenase (NAD+) [Solanum tuberosum]
Length = 470
Score = 512 bits (1319), Expect = e-144
Identities = 251/410 (61%), Positives = 320/410 (77%), Gaps = 3/410 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
SKI+V +PIVEMDGDE TRVIWK+IK+KLI PYL++D KYYDL I RD T+DQVT +S+
Sbjct: 60 SKIRVQNPIVEMDGDEMTRVIWKMIKDKLIYPYLELDTKYYDLGILNRDATDDQVTVESA 119
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
ATLKY VAVKCATITPDE R+KEF LK MWKSPNGTIRNIL GTVFREPI+ IPR+V
Sbjct: 120 EATLKYNVAVKCATITPDETRVKEFGLKSMWKSPNGTIRNILNGTVFREPILCTNIPRIV 179
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+KPI IGRHAFGDQYRATD I GKL++ F ++G+ ++L VY+F K GIA+A
Sbjct: 180 PGWKKPICIGRHAFGDQYRATDRIINGPGKLKMVFVPENGESPMELDVYDF-KGPGIALA 238
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+N + SI+ FA++S +A +K PL+ +TKNTILK YD +FK IF ++++++K++F+
Sbjct: 239 MYNVDQSIRAFAESSMSMAFSKKWPLYLSTKNTILKKYDGRFKDIFQEVYEEKWKQQFEE 298
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD++AQGFGSLGLMTSIL++ DGK
Sbjct: 299 HSIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLLAQGFGSLGLMTSILLSSDGK 358
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVT HFR HQ+G+ETSTNS+ASIFAWT+ + R +LD +++F + LE
Sbjct: 359 TLEAEAAHGTVTIHFRLHQKGQETSTNSVASIFAWTKGLGHRAQLDGNQKLLEFVHTLEA 418
Query: 362 ATLDTVQVGGKMTKDLALMLG-KTNRSSYVTTEEFIDEVAKRLQNMMLSS 410
+ + T++ GKMT L G K +R Y+ TEEFID VA++LQ + +S
Sbjct: 419 SCIGTIE-SGKMTNLAILAHGSKVSREFYLNTEEFIDAVAQKLQEKLHAS 467
>gi|5042455|gb|AAD38292.1|AC007789_18 (AC007789) NADP-dependent isocitrate dehydrogenase [Oryza sativa]
Length = 414
Score = 511 bits (1317), Expect = e-144
Identities = 253/407 (62%), Positives = 312/407 (76%), Gaps = 5/407 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KI V +P+VEMDGDE TRVIWK IK+KLI P+LD+D+KYYDL + RD T D+VT +S+
Sbjct: 5 KIVVANPVVEMDGDEMTRVIWKWIKDKLIFPFLDLDIKYYDLGLPNRDATGDKVTIESAE 64
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLKY VA+KCATITPDE R+KEFNL MWKSPNGTIRNIL GTVFREPII IPRLVP
Sbjct: 65 ATLKYNVAIKCATITPDEGRVKEFNLSAMWKSPNGTIRNILNGTVFREPIICKNIPRLVP 124
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHAFGDQYRATD IK GKL+L F D +E I+L V+ F +GG+A++M
Sbjct: 125 GWIKPICIGRHAFGDQYRATDTVIKGPGKLKLVF--DGREEQIELDVFNFTGAGGVALSM 182
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI FA+AS +A +++ PL+ +TKNTILK YD +FK IF ++ +++ KF
Sbjct: 183 YNTDESIWAFAEASMNMAYQKRWPLYLSTKNTILKKYDGRFKDIFQENYETKWRAKFDDA 242
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD++AQGFGSLGLMTS+L+ PDG+T
Sbjct: 243 GIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDLIAQGFGSLGLMTSVLVCPDGRT 302
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAWT + R KLD+ ++ F LE A
Sbjct: 303 IEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTTGLGHRAKLDDNKRLLDFVQKLEAA 362
Query: 363 TLDTVQVGGKMTKDLALMLGKTN--RSSYVTTEEFIDEVAKRLQNMM 407
+ TV+ GKMTKDLAL++ N R Y+ T EFID VA+ L+ +
Sbjct: 363 CVGTVE-SGKMTKDLALLVHGPNVSRDKYLNTVEFIDAVAEDLRTRL 408
>gi|13470357|ref|NP_101923.1| (NC_002678) NADP-dependent isocitrate dehydrogenase [Mesorhizobium
loti]
gi|14021096|dbj|BAB47709.1| (AP002994) NADP-dependent isocitrate dehydrogenase [Mesorhizobium
loti]
Length = 403
Score = 509 bits (1311), Expect = e-143
Identities = 248/407 (60%), Positives = 316/407 (76%), Gaps = 5/407 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGDE TR+IW+ IK+KLI PYLD+ L+YYDL I+ RD TNDQVT DS
Sbjct: 1 MAKIKVANPVVELDGDEMTRIIWQFIKDKLIHPYLDLKLEYYDLGIEHRDATNDQVTIDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDE R++EF LK+MWKSPNGTIRNILGGT+FREPII+ +PRL
Sbjct: 61 ANAIKKYGVGVKCATITPDEQRVEEFKLKKMWKSPNGTIRNILGGTIFREPIIMKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPII+GRHAFGDQYRATD + GKL ++F +DGK I+ V++ P G+AM
Sbjct: 121 VPGWTKPIIVGRHAFGDQYRATDFRFPGKGKLTIKFVGEDGKV-IEHDVFDAP-GAGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+N ++SI+ FA+AS L R P++ +TKNTILK YD +FK IF +++ E++ F+
Sbjct: 179 AMYNLDESIREFARASLNYGLLRNYPVYLSTKNTILKAYDGRFKDIFQEVYEAEFEADFK 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
+ K+ YEHRLIDDMVA LK GG++ A KNYDGDVQSD VAQGFGSLGLMTS+L+TPDG
Sbjct: 239 SKKLWYEHRLIDDMVASSLKWSGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+GEETSTNSIASIFAWTR + R KLD+ ++ +F LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQHQKGEETSTNSIASIFAWTRGLAHRAKLDDNAELKRFAETLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
K + TV+ G MTKDL+L++G +++T F+D++ + LQ M
Sbjct: 359 KVCIQTVE-SGFMTKDLSLLIGPDQ--PWLSTTGFLDKIDENLQKAM 402
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF
Posted date: Mar 6, 2002 1:29 AM
Number of letters in database: 279,182,324
Number of sequences in database: 891,607
Lambda K H
0.319 0.136 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 225,020,022
Number of Sequences: 891607
Number of extensions: 9465184
Number of successful extensions: 22644
Number of sequences better than 10.0: 328
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 250
Number of HSP's that attempted gapping in prelim test: 22416
Number of HSP's gapped (non-prelim): 347
length of query: 420
length of database: 279,182,324
effective HSP length: 123
effective length of query: 297
effective length of database: 169,514,663
effective search space: 50345854911
effective search space used: 50345854911
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 72 (32.3 bits)