Genbank Search Results For Hexokinase

Glycolysis is a process that occurs in the cells of many different organisms and yields energy from the splitting of glucose.  Hexokinase is an enzyme used in the first step of glycolysis.  When glucose enters the cell, hexokinase phosphorylates the glucose.  It does this by removing a phosphate group from ATP and adding it to the sugar.  The addition of the phosphate group does two things that are important in the remaining steps of glycolysis. First it makes glucose more chemically reactive and second, it traps the sugar inside the cell by adding electrical charge to glucose so that it is not permeable to the cell membrane.

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Glycolysis is common among many species so many species possess the enzyme hexokinase but the protein may be different in different species. It is often useful to compare the protein sequence and hence the nucleotide sequence of hexokinase in different species.  The table below compares homo sapiens, bos taurus, Yarrowia lipolytica, arabidopsis thaliana, and mus musculus.
Organism Nucleotide Sequence Amino Acid Sequence
Homo Sapiens mRNA, complete cds yes
Bos taurus mRNA, complete cds yes
Yarrowia lipolytica mRNA yes
Arabidopsis thaliana mRNA, complete cds yes
Mus musculus mRNA, complete cds yes

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