General Sites
Need Background Information? Places to start looking? Definitions for terms?

Association of Biomolecular Research Facilities
http://www.abrf.org/
Contains links to descriptions of methods. Could be helpful for understanding journal articles

Biology Website references for student's and teachers
http://www.hoflink.com/~house/index.html
Billed as 'Over 4,100 sites in thirteen biological areas Hyperlinks checked frequently for accessibility'

Cell Biology Dept—U of Texas medical branch
http://cellbio.utmb.edu/cellbio/lysosome.htm
If enter this site and use "return to menu’ at bottom -- links to many topics covered in their cell bio course

Cell and Molecular Biology Online
http://www.cellbio.com
good general link to many other websources

Dictionary of Cell Biology
http://www.mblab.gla.ac.uk/~julian/Dict.html
Was that ribosome or rhizome? Check the dictionary and see which fits.

InScight Discussion topics
http://www.apnet.com/cgi-bin/netforum/inscight/a/1
Discussion groups on a variety of topics brought to you by Academic Press

UCSD --Scott Emrs lab web site.
http://cmm.ucsd.edu/emr/lab/
Cool picture and some good links including databases and online journals-- no password necessary to browse.

The Scientist-News Journal with free subscription available
http://www.the-scientist.library.upenn.edu/homepage.htm
Can hit on just about every topic depending on the issue

The Biology Project
http://www.biology.arizona.edu/default.html
Cell cycle link from here but good for others too

Yale- Peter Novick’s Lab Homepage
http://info.med.yale.edu/cellbio/Links.html
Links to journals, databases, career links (back up a link and get info on his lab’s work in vesicular traffic)
Scroll down past all of the Yale specific links to the Cell Bio ones.

Pedro's BioMolecular Research Tools
http://www.public.iastate.edu/~pedro/research_tools.html
Has a whole section of links to Guides and Tutorials

PubMed
www.ncbi.nih.gov
This is a good link to find articles about certain areas.The site itself gives abstracts of the articles and provides some links to see the online versions of the articles. Definitely a 5 if you are looking for articles

Biological membranes
http://www.biology.arizona.edu/cell_bio/problem_sets/membranes/index.html
This site provides a variety of detailed information regarding the components of cellular membranes. There are also some links to sites that provide thorough explanations of diagrams and photos as well.
Overall Rating: 5

http://cellbio.utmb.edu/cellbio/membrane.htm#Menu
This site is helpful because it allows you to select different concepts about the cell membrane from a main menu. Each concept then includes a detailed but concise summary and helpful diagrams and pictures. There is also a quiz included to help you review the important ideas about the cell membrane along with an overall summary. Overall Rating: 4

http://www.cbc.umn.edu/~mwd/cell_www/chapter2/membrane.html#PHOSPHOLIPIDS
This site is useful because it is well organized with headings about each of the components of the cell membrane. Each component is explained briefly; therefore, this site would be helpful for a quick, last minute review. Key terms and concepts have links that let you view the definitions.
Overall Rating: 4

http://www.bact.wisc.edu/MicrotextBook/BacterialStructure/MembraneGen.html
We recommend this site because it contains straightforward explanations of concepts accompanying bold, colorful images. However, this site concentrates on lipids and barely mentions the function of the proteins in describing the lipid bilayer. Definitions can be accessed for key terms via links.
Overall rating: 3

http://fhis.gcal.ac.uk/BIO/micro/drjrattray/cab1lec.summ/membranes.home.html
This site is helpful because it is organized well with detailed explanations about the components of the cell membrane. However, this site does not have colorful pictures to help the viewer visualize the concepts.
Overall Rating: 3

http://www.usd.edu/~bgoodman/Membrane.htm#figure
This site provides an attractive, colorful overview of the cell membrane but only fully explains phospholipids and some of the functions of the cell membrane. The information is too general, and the links for other cell membrane sites do not work well.
Overall rating: 2

http://library.thinkquest.org/C004535/cell_membranes.html
This site provides a concise summary for a very basic understanding of the cell membrane along with some good images. Even though lipids and phospholipids are explained well, the site drifts away from detailed explanations about proteins to types of transport. The site has an interesting feature called “discuss this topic” that allows you to post questions about the cell membrane. (Note: You must click “Cellupedia, click here to view this site” which is in the middle of the web page.)
Overall rating: 2

http://esg-www.mit.edu:8001/cgi-bin/biosearch.pl?membranes
This link brings you to all pages within the MIT hypertextbook which contan mention to biological membranes.For the more general link to the hypertextbook webpafe, followhttp://esg-www.mit.edu:8001/esgbio/7001main.html.The site is almost all text, but is interspersed with helpful links which bring you to definitions of unknown words.

http://blanco.biomol.uci.edu/Bilayer_Struc.html
A very good yet highly technical discussion of fluid lipid bilayers.If the high school textbook answer just doesn't do it for you, come here for a much more detailed analysis of structure and function.

http://cellbio.utmb.edu/cellbio/membrane.htm#Menu
This is a site full of discussion on a variety of topics concerning cell membranes, from historical perspective to surface specializations.While navigating the site is not as intuitive as one may like, the vivid, informative graphics and plentiful information make this site a useful resource providing a general overview of biological membranes.

http://www.jdaross.mcmail.com/cell2.htm
A good general overview of cellular membranes composed of phospholipid bilayers. First section addresses the form and components of the membrane, including a good drawing of a phospholipid. Second section addresses the Fluid Mosaic Model and integral membrane proteins, with a diagram included. Also discusses the semi-permeable property of membranes. The information is easy to understand, save for a few grammar mistakes. Also, the author switches between using “bilipid layer” and “lipid bilayer,” which can cause confusion.
Rating: 3

http://sun.menloschool.org/~cweaver/cells/c/cell_membrane/
Another general overview site. Very nice, professional diagrams, most likely scanned from textbooks. Contains a little more information of the communication functions of the membrane, including membrane receptors. Site is well-made and neat, but doesn’t contain heaps of information. Best used for its diagrams.
Rating: 3

http://www.omedon.co.uk/ionchan/
Complete with introduction and tabbed sections, this site offers a great explanation of ion channels, and a limited but detailed description of plasma membranes including chemical diagrams and colored images. Gives a reasonable explanation for the transport of material across the membrane including how toxins manage to “fool” the cell membrane. It also gives a listing of other websites for further information. One downfall is the Potassium Protein illustration does not seem to load well which is a weakness. Overall the site is very informative.
Rating: 4

http://www.bact.wisc.edu/MicroTextbook/BacterialStructure/Membranegen.html
This site gives you a little of everything. It begins with an overall outline of the cell membrane, its components and structure. Great vibrant images animating the parts of the cell membrane are available as well as multiple pages following the first detailing more aspects of the plasma membrane. The site details the different types of membrane proteins and the functions of a cell membrane. This is a very well rounded site with lots of information. If you are looking for a general overview of all aspects of the membrane it is fantastic, if looking for detailed descriptions, it may lack a bit.
Rating: 4

http://cellbio.utmb.edu/cellbio/membran3.htm
This is an above average site with color-coded pictures about vocabulary such as lipid bilayer, transmembrane proteins, microvilli, and unit membrane. These vocab words link to another site that details information abou tthat specific vocab word. Also has links to other sites with informaiton about membranes.
Rating: 5

http://home.earthlink.net/~dayvdanls/cell_membranes.htm
This site contains a large amount of other topics such as the fluid mosaic model, passive and active transport, water potential, dialysis, osmosis, etc. Includes chime images, 3D models, and labeled pictures of membranes, junctions, and diffusion to name a few.
Rating: 5

Protein Synthesis
http://www.tusculum.edu/faculty/home/ivanlare/html/101/15.html#nul
We rate this a 3 out of 5 because it gives a good basic overview of the topic but doesn’t offer a complete explanation. A little juvenile, but it is good for easy reference (mostly an outline).

http://wsrv.clas.virginia.edu/~rjh9u/trtrpict.html
We rate this web site a 4 out of 5 because it provides a visual aid and supplements it with basic notes. Visually presents all of the steps of translation and clearly displays all of the components involved.

http://wsrv.clas.virginia.edu/~rjh9u/gif/protein.mov
We rate this website a 5 out of 5 because it can be retrieved easily from the Davidson Biology 111 website. The animation performs all of the actions involved in protein synthesis. The site is completely visual and clear.

http://www.accessexcellence.org/AB/GG/protein_synthesis.html
We also give this website a 5 out of 5 because it, in a different way, thoroughly demonstrates protein synthesis with images and brief definitions. The website provides a good quick reference for easy vocabulary definitions and understanding.

http://tidepool.st.usm.edu/crswr/protsynthmov.html
We give this site a 4 out of 5 because it the most in depth of the sites, but there seems to be too much going on to focus. Information wise, the website engages the reader more, but the animation is not as pleasing to the eye.

http://www.indstate.edu/thcme/mwking/protein-synthesis.html 
This is a very long site with very detailed info about Translation. Nothing really on Transcription though, which is a little disappointing. It also come from what looks like a reputable source( Indiana State)
 
http://tidepool.st.usm.edu/crswr/protsynthmov.html 
This website has is very short but has a helpful animation about the processes of Transcription and translation. Below the animation is a brief description of what goes on. It also has a glossary of words that are highlighted and concept that are not obvious.
 
http://web.jjay.cuny.edu/~acarpi/NSC/12-dna.htm  
This website is not too intense but I like it because it seemed easy to use and get a good overview of what we are looking for.

http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/A/A.html
This is the general index of this site, with almost every technical bio term you could imagine - cool just in general, not just for our topic. Again, provides many links between its pages where appropriate.

http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/T/Transcription.html 
This highly detailed site talks about transcription in DNA and RNA, providing the steps, types of RNA, RNA polymerases, RNA processing (pre-mRNA and mRNA, includes a diagram), split genes, and splicing. This site is very good with links within its own pages (the Biology pages are immense) - most key terms have their own link and are explained in more detail, often with illustrations. There is an idex to each page at the top - very helpful. There are also links to EM images.

http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/T/Translation.html
Part of the previous site, this page details Translation from sequences of nucleotides to RNA codons, the steps of translation (initiation, elongation, and termination: with illustration), polysomes, and quality control (mutations, "errors", decay, and their mechanisms). Both pages also have quick and easy summaries at the bottom of the page.

http://www.eurekascience.com/ICanDoThat/protein_syn.htm
This site has very simple explanations and is in narrative style, aimed at younger readers; therefore it is actually quite entertaining to read and provides a good basic overview of the complicated process of protein synthesis. Obviously its technical information is not as in depth as the other sites, but it is a good beginner site with cool little moving animations.
 
http://www.accessexcellence.org/AB/GG/protein_synthesis.html
Cool diagram of protein synthesis and briefly describes (and shows location of) transcription and translation: lots of info packed into this drawing. Leads to a graphics gallery that could be quite helpful, in a myriad of cellular topics:
http://www.accessexcellence.org/AB/GG/#Anchor-From-14210

http://gened.emc.maricopa.edu/bio/bio181/BIOBK/BioBookPROTSYn.html
This site gives a tremendous amount of information, including a bit of a history lesson and numerous color scans of the process of protein synthesis. It's links at the top provide a good general resource and the those at the bottom provide even more specific information on protein synthesis.

http://www.ncc.gmu.edu/dna/ This site is a great general resource with brilliant animations hidden within the sections of the site.It's information is not very technical, but the step by step explanations of the process of synthesis is very helpful for visualization.

http://web.indstate.edu/thcme/mwking/protein-synthesis.html#interferon -- Protein Synthesis.Although the layout of this website is not particularly captivating -- it consists of a long page of text with a navigation bar at the top functioning as a table of contents and is occasionally infused with colorful graphics -- it contains a wealth of information about the specific mechanisms of transcription and translation as well as regulation mechanisms.Each individual step in the process -- from characterization of tRNAs and amino acid activation to elongation and termination are described at length.Finally at the end of the website, the different mechanisms of translation regulation are described.The website explains regulation of translation by Heme, interferons, iron and antibiotics.Overall, this website would be a good one to read for a person interested in the regulation cascades of translation and in learning the specific translation mechanisms.

http://tidepool.st.usm.edu/crswr/initiation.html -- Initiation of Protein Synthesis
This link points to an animation by a professor at the University of Southern Mississippi illustrating the process of protein synthesis initiation.This animation is actually a really good one, showing clearly the specific steps and processes involved in translation.

http://ntri.tamuk.edu/cell/regulation.html -- Regulation of Protein Synthesis
A website maintained by the Natural Toxins Research Center at Texas A&M University - Kingsville.This site contains an advanced genetic explanation of protein synthesis regulation -- and is infused with helpful tables, graphics and figures that make the topic interesting and the site easy to read.The site gives an advanced explanation of transcriptional regulation in eukaryotes -- and explains current protocols for studying this process, as well as an explanation and characterization of the genes involved.The site explains regulation using steroid hormone receptors, homeotic gene receptors, and cooperative regulation of the serum albumin gene.Overall the site contains a well organized and interesting set of information regarding regulation of protein synthesis -- and would be a good resource for a geneticist looking for more advanced information or graphics regarding the subject.The only problem with the site is that it contains no navigation bar nor an extensive list of outside links to more information.

http://www.uga.edu/cellbio/FacultyPages/Keith.htmDr. Bernd, this site was not part of my project but I found it and was intrigued by it because it gives some information on a lab at the University of Georgia that is busy studying cytoskeletal growth.This is a topic that no one in our lab section was researching and I wasn't sure if anyone had found any information for you regarding this topic.Anyway, it's just the homepage for a researcher interested in this topic and has some pdf links to papers that are representative of his work.

Protein targeting
http://www.csus.edu/indiv/b/ballardr/Lecture%206%20-%20Protein%20Localization.doc
This is an online lecture for another college that provides a very good detailed outline of the material, and summary questions for the students to make use of. It also seems to make the class interactive with the discussion questions as well. Score: 5

http://www.wikipedia.com/wiki/Protein_targeting
Good overall explanation of key terms of topic. It also provides links to terms and definitions that users might find useful. Gives the general concept of the topic and presents it in an easy way. Score 5

http://www.udallas.edu/biology/Ganter/molbio/proteinprocessing.html
This site provides a good outline for the topics. To learn the topic and be able to recite the details of the small phrases provided most likely means you understand the material well. Score: 3

http://www.upci.upmc.edu/internet/news/reuters/reuters.cfm?article=650
This site incorporates the topics like protein localization and shows how this topic is applied in the real world. Current research processes are based upon developments and techniques of this topic. Score: 3

http://www2.musc.edu/Pharm/sig_seq_review.pdf This looks like an article from a science journal with specifics of the topic for other researches to learn and use. It is very difficult to understand and more for the use of advanced scientists. It is complete in structure, diagrams, acknowledgements and citations. Score: 4

http://anx12.bio.uci.edu/~hudel/bs99a/lecture27/lecture8_2.html This website provides a basic outline of protein targeting, delineating between post-translational and co-translational targeting.It also includes simple, easy to read diagrams of the process, and outlines how targeting works with cellular components.The site also gives information about the secretory pathway, providing a detailed disagram of the process.While it does not have full explanations to the process, it provides useful outlines and diagrams to complement the study of protein targeting.We would rate this website as a 4.0.

http://www.islandone.org/Foresight/Conferences/MNT05/Papers/Wendel/ This link offers a case specific application of protein targeting.It investigates an alternative to standard chemical signals in the hope a more useful messenger system could be utilized.The website assumes that the reader already possesses a general understanding of protein targeting.The information is specific and uses concepts of protien targeting to explain the study.Since the author already assumes his/her audience maintains an understanding of protein targeting, no diagrams or illustrations are provided within the article.This is an example where one may go to build an understading of protein targeting after they have already built the foundation.We give this website a 2 for its overall rating.

http://www.mun.ca/biochem/courses/3107/Lectures/Topics/Folding_etc.html This website presents protein synthesis in an organized outline form, with protein targeting as a sub-category of the outline.The few charts and graphs provided by this website are helpful, but not impressive.While this website focuses on the general topic of protein synthesis, it's material and vocabulary is fairly specific.It breaks down protein synthesis into four categories: folding, modification, targeting and degredation.We rate this website a 3.

http://web.indstate.edu/thcme/mwking/protein-modifications.html This website focuses on post-translational modifications specifically.Although it does not talk directly about protein targeting, it does address the important process of altering proteins that would be necessary for any targeting.The page includes information about glycoproteins, acylation, methylation, sulfation, Vitamin C-dependent modifications, and selenoproteins.While the information on the page is more detailed, the content is readable at the undergraduate level.We would rate this page a 4.5 to 5.0.

Other Links
http://www.biomed2.man.ac.uk/stirling/protein_targeting_to_the_endopla.htm
http://www.oup-usa.org/isbn/0199637415.html
http://fstgal12.tu-graz.ac.at:7777/pls/al12/ypl.detailinfo
http://bioresearch.ac.uk/browse/mesh/detail/C0887827L1772874.html
http://yakko.bme.virginia.edu/biom304/notes%5Cathero_sorting.htm

Intracellular trafficking (vesicular traffic)

http://rex.nci.nih.gov/RESEARCH/basic/lm/trafficking.htm This is a research site by a team that studies the molecular mechanisms that control intracellular trafficking of a particular protein.The site includes fairly good illustrations of vesicular trafficking, as well as the cell cycle. Rating: 2

http://bioinfo.weizmann.ac.il/_ls/zvulun_elazar/zvulun_elazar.html This site is a research abstract from a group whose main goal was to "identify novel factors directly participating in vesicular protein trafficking."The site includes a good image of a vesicular transport scheme on the exocytic pathway.The site is relatively specific, but the diagrams are clearly drawn and labeled and could be useful for visualizing the pathway. Rating: 3

http://dir.nichd.nih.gov/cbmb/pb1labob.html This site is an excellent collection of movies entitled "ER to Golgi Traffic Visualized in Living Cells."The series of movies tracks a viral glycoprotein moving through a secretory pathway to the cell surface.Although the subject is fairly specific, the images are excellent and show the movement of the protein very clearly. Rating: 5

Cellular Scaffolding
http://www.uga.edu/cellbio/FacultyPages/Keith.htm
Dr. Bernd, this site was not part of my project but I found it and was intrigued by it because it gives some information on a lab at the University of Georgia that is busy studying cytoskeletal growth.This is a topic that no one in our lab section was researching and I wasn't sure if anyone had found any information for you regarding this topic.Anyway, it's just the homepage for a researcher interested in this topic and has some pdf links to papers that are representative of his work.

http://nessie.bch.ed.ac.uk/PAUL/ACTIN/
This site is an applet that allows you to create your own actin structure.  The instructions for the applet are straight forward and clear.  Rating 3.75.
 
http://www.ks.uiuc.edu/Research/cell_motility/actin/
This sites has  quicktime movies that show the primary and secondary structures of the cell scaffolding.  The Site is easy to browse and asthsticely pleasing.  Rating 4.00.
 
http://genome-www.stanford.edu/group/botlab/people/amberg/actin_images.html#BudSite
This is by far our most favorite site.  There are movies to download that cover the entire life time of yeast cells which show empahsis on the cell scaffolding.  Rating 5.00.
 
http://www.cytoskeleton.com/abactlg.htm
This is a basic overview of actin and the cytoskeleton.  This is a good site for a general information on cell scaffolding.  Ratine 3.85.
 
http://www.itg.uiuc.edu/technology/atlas/structures/actin/
This is a one page site that shows stained pictures of the actin and microtubles in a cell.  Rating 3.00.

Molecular motors

http://physiology.med.uvm.edu/warshaw/
In the techniques section, there is animation next to a microscopic video image of the technique. The candid photos of the researches gave it a personal touch.
Rating: 3.5

http://motility.york.ac.uk/
This site is very in depth with lots of links to other good sites. It also has good images, animations, and even recordings of a myosin molecule.
Rating: 5

http://www.cse.ucsc.edu/~hongwang/ATP_synthase.html
This site has a good animation. Also, an in-depth image with labels of the parts of an F1 molecular motor of ATP synthase. The description in this site is average and the site has fewer links than others.
Rating: 3

http://mc11.mcri.ac.uk/ebiochem.html
The site has lengthy, detailed descriptions of the mechanisms of the motor and the biochemistry of the motors. However, there are no images on this site.
Rating: 4

http://www.mih.unibas.ch/Booklet/Booklet96/Chapter2/Chapter2.html
This site shows a good research project. The images are well described, and it ends with a good bibliography so you can find more information on molecular motors.
Rating: 3.5

http://www.rpi.edu/locker/25/001225/public_html/nanowebprojects/jason/
This site has informative descriptions and animations of the muscle movement. The site covers linear and rotational motor molecules. Many links to other related topics and background information are included.
Rating: 5

http://motility.york.ac.uk/ Rating: 4.5
This is the web page of the Dept. of Molecular Motors at the University of York., which has links to a list labs working on molecular motors. The site also contains many clear and exciting animations in color.

http://www.nhlbi.nih.gov/labs/molecularcardiology/motility.htm Rating: 3
This is the National Heart, Lung and Blood Institute’s website for their Cellular and Molecular Motility Section. This link contains instructions and illustrations of how to conduct a motility assay using actin and myosin. It also contains a detailed, color, three-dimensional illustration of the surface proteins and filaments and their interaction during the motility assay.

http://scop.mrc-lmb.cam.ac.uk/scop/data/scop.b.html Rating: 4
This is from the Structural Classification of Proteins website. This is a hierarchy of protein families containing three-dimensional Chime images of each protein, not specifically motor proteins.

http://mc11.mcri.ac.uk/khome/index.html Rating: 3
This is the kinesin homepage which contains links a movie page featuring animations of many proteins as well as detailed descriptions and explanations the functions and behaviors of different proteins.

http://www.sci.sdsu.edu/movies/actin_myosin.html Rating: 5
A three-dimensional, high resolution animation of an actin myosin crossbridge by the San Diego State University of the Sciences. We found this link at the following website which contains a list of helpful links on Myosin, Motility, Muscle and Cytoskeletal Groups a.k.a the Myosin People. (http://www.mrc-lmb.cam.ac.uk/myosin/muscleww.html)

Site #2: A University of Vermont research group devoted to the study of molecular motors as they apply specifically to the actin-myosin muscular complex.
http://physioweb.med.uvm.edu/Physioweb.php3?menu=Research
This site is a portion of the University of Vermont’s website that is devoted to the research efforts of a group of professors. Each lab’s link contains an abstract of that lab’s particular research goals and ideas. These interests lie overwhelmingly with the study of myosin and how it relates to actin and ATP on a molecular basis.The site also focuses on permutations of myosin type and structure and how that relates to overall muscle function.The site contains a little highly technical information about each research topic, but there is enough background provided. Literature citations are included as well as animations of various techniques for investigating myosin contraction.We ranked this site as our second favorite.

Site #3: A cell diagram showing molecular motors.
http://faculty.plattsburgh.edu/donald.slish/Motors.html
This site, a portion of Professor Donald Slish’s website at Plattsburg State University, contains a diagram of a mitotic cell, which contains links to close-up animated views of molecular motors contained thoughout the mitotic cell. Though not providing much in the way of technical or even background information, the site provides an easily explicable view of “why molecular motors are important.” The site made the list simply because of its good use of applying molecular motors to the cell cycle and by virtue of its cool animation. We rate it a 3.

Intracellular signaling

WWW Virtual Library of Cell Biology
www.vlib.org/Science/Cell_Biology/signal_transduction.shtml
This website gives a host of other links to web pages for specific types of signal transduction.Some examples include "The Learning Pathway: Cyclic AMP Second Messenger System" and "Regulators of Signal Transduction Pathways." Probably a 5 because it provides some great links.

Lecture Notes at MIT
http://web.mit.edu/7.06/www/2001-Lectures/Lecture6/index.htm
These are notes from a lecture at MIT entitled "Signaling: From the Cell Surface To the Nucleus."The notes are in slide format and include some great graphics.Excellent.This is a 5.The notes are really helpful and are specific to the topic of intracellular signaling, but there are other notes on this same site that would be helpful for other topics.

Cell Signaling Networks Database
http://geo.nihs.go.jp/csndb
This is a good database of a number of signaling pathways that one can actually enter a query to find.This ranks as a3 because once I started using it, it turned out not to have the specifics that I was looking for.Not quite user-friendly.

The Yeast Pheromone Signal Transduction Pathway
www.bri.nrc.ca/thomasweb/sigpath.htm
This is a great graphic of this particular pathway.Clicking on any molecule in the picture also provides a brief description of that molecule and its role in the pathway.5!And pertains to our lab.

http://www.ascb.org/news/vol24no4
(After accessing this directory, click on the April-01 pdf file link.)
This article is about Jennifer Lippincott-Schwartz, specifically about her decision to become a cell biologist and to research intracellular trafficking.Rating: 4

http://www.mpi-dortmund.mpg.de/departments/dep2/kipp/rechts1.php3
This site is another research abstract from a group of German biologists that are studying intracellular trafficking in epithelial cells.The article is quite detailed, but includes good descriptions of how trafficking operates and is regulated. Rating: 3

Extracellular communication

Cell Biology.com: Cellular Communication- 5
http://www.cell-biology.com/cellcom.html
This general overview of intercellular communication discusses the various forms of communication (endocrine, paracrine, etc.) and the types of receptors and receptor mechanisms used to transmit these extracellular signals into a change in function for a cell. Within the text of the page are links to useful pages on related topics.

Cell Signaling Pathway Slides- 4
http://www.sial.com/Area_of_Interest/Life_Science/Cell_Signaling/Pathway_Slides_and_Charts.html
This website contains links to pages with diagrams and text relevant to many processes in cell biology (apoptosis, cell cycle, gene expression regulation, etc.) that are controlled by both intercellular and intracellular signaling. The slide “Cytokines, Growth Factors, and Hormones” contains information more specifically relevant to intercellular communication.

Journal of Neuroscience:
Control and Plasticity of Intercellular Calcium Waves in Astrocytes: A Modeling Approach- 2
http://www.jneurosci.org/cgi/content/full/22/12/4850
From the Journal of Neuroscience online, this article gives a technical discussion of a specific form of intercellular signaling. Despite its specificity, the article also discusses general methods of intercellular signaling like transmission across gap junctions and through extracellular space. It discusses the complexity of the control networks required for effective communication between cells.

“Intercellular Communication”- 1
http://www2.mrc-lmb.cam.ac.uk/pandfpages/pfic.html
The beginning paragraph of this site is a good general definition of intercellular communication. The site also provides specific examples of intercellular and intracellular communication and other chemosensory examples from organisms like Drosophila. The information is very general.

“Cell to Cell Signaling”- 4
http://www.shsu.edu/~bio_bls/signal.htm
This site contains an in-depth outline covering the mechanisms involved and chemicals used in intercellular communication. The site contains clear definitions of the major types of intercellular signaling and detailed information about specific signaling molecules.

“Introduction to Hormones and other Signaling Molecules and their Receptors”- 5
http://web.mit.edu/7.06/www/2001-Lectures/Lecture5/sld001.htm
This site contains a slide show in which slides 1 through 6 deal with intercellular signaling. There are good diagrams of the types of intercellular signaling such as signaling by membrane attached proteins, as well as autocrine, paracrine, and endocrine signaling.

http://lifesci.rutgers.edu/~fong/15.htm
This website gives a general overview of the mechanisms and molecules involved in extracellular communication, with specific emphasis on signal transduction pathways.It has a lot of information with keywords and phrases highlighted for emphasis.

http://www.shsu.edu/~bio_bls/signal.htm
This link provides another overview of cell-to-cell communication mechanisms.The page covers types of signalers, receptors, and pathways involved in the many varieties of cellular communication.

http://www.vacadsci.org/PUB/chap41.pdf
This website outlines the chemical signals used in intracellular communication.It deals mostly with the glands that produce the signals and the signals themselves.Although is does not focus on the details of the pathways, it gives a thorough description of the general processes that are occurring during extracellular communication.

http://www.whatislife.com/reader2/chapter_summary.htm <http://www.nysaes.cornell.edu/fst/faculty/acree/pheronet/pherom.html
This site offers general summary of cell membrane transport and signaling.Gives links to the principles and applications of the components of the cell membrane.

http://www.sci.sdsu.edu/classes/bio366/TFrey/CellSignal1/sld002.htm
This site gives a pictorial representation of three general types of extracellular signaling.It aids in the visualization of the processes.

Protein Degradation

http://www.neuro.wustl.edu/neuromuscular/mother/degrade.htm 
A convenient outline with links to extra sites about key words, this site includes detailed explanatory pictures and examples of proteins.  It also outlines the steps in the degradation process.  It's easy to read; we rate it an excellent: 5.
 
http://vlib.org/Science/Cell_Biology/proteins.shtml
This site is primarily an extensive list of both general and topic-specific links to other sites.  The links contain a broad range of information, with introductory and detailed explanations of protein degradation.  There are also some links to discussion groups.  We give this site a very good: 4.
 
http://www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb2/part1/protease.htm
This site is a general overview with color coded key words, definitions, and a few helpful pictures, though mostly writing.  It contains details on ubiquitin and various proteases and can also be viewed as slide show.  It would be good for basic research; we give it a very good: 4.
 
http://www.mol.biol.ethz.ch/praktikum/lecture2.pdf 
This site is a very detailed powerpoint presentation with lots of detailed pictures and extensive information on ubiquitin and proteasomes.  We give it an excellent: .5
 
http://www.aecom.yu.edu/cuervo/aging_and_protein_degradation.htm 
This site draws a connection between aging and protein degradation.  It's a general overview page with links to more detailed sites about aging, protein degradation, lysosomes, and mediated autophagy.  We rate it a good: 3.
 
http://depts.washington.edu/sfields/yplm/data/DegWallRnaprocMat.pdf
This is that picture of the network of interacting yeast proteins.

Cell Cycle
http://www.biology.arizona.edu/cell_bio/tutorials/cell_cycle/main.html
This site was a concise and easy to navigate tutorial. It is presented in outline format and clearly describes each cell stage. There are vocabulary links to further explain each event in the cell cycle, as well as having pictures and diagrams.
 
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/CellCycle.html
This site was presented in outline format with no paragraphs. In text links offer more in depth information without hindering a general overview of the cell cycle. It is easy to find specific details through links.

http://www.cellsalive.com/cell_cycle.htm
This site was easy to read and had good visuals with animation. It did not contain as much information as the first site, because the information was even more concise. The site was colorful and offered links to do searches for more detailed information.
 
http://www.ndsu.nodak.edu/instruct/mcclean/plsc431/cellcycle/cellcycl1.htm
An alternative diagram to the cell cycle is presented here. Detailed specifics on proteins are offered, and the site is designed to explain the cell cycle in terms of cancer. There are some useful definitions and links to other detailed topics, such as cancer.

http://www.geocities.com/CollegePark/Lab/1580/cycle.html
 Here you will find good basic information. The site is harder to read due to its busy background. It is presented in a type of outline, with paragraphs as well. It took longer to read than the other sites.

http://www.people.virginia.edu/~rjh9u/cdk.html
"Cell Cycle Control Points and Cancer" depicts and describes the cell cycle phases as well as the function and mechanism of cell cycle checkpoints; it also describes how mutant genes, when capable of removing or effecting a checkpoint or transcription inhibitor, can lead to tumor development.  Diagrams of the cell cycle and the effect that mutations have on it are provided, as well as links to cell cycle control in the yeast Schizosaccharomyces pombe.

Apoptosis
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/A/Apoptosis.html
This website is a detailed outline explaining what apoptosis is – how cells die (injury or suicide – programmed cell death), why cells goes through apoptosis, the mechanisms of apoptosis. It has two great diagrams (of how apoptosis occurs with an external signal and how apoptosis occurs with a target recognition system) and gives examples of diseases in which apoptosis occurs.
Grade – 5

http://www.cellsalive.com/apop.htm
While containing an amusing animation, this website is not very helpful. It mentions the role of apoptosis in the immune system pertaining to neutrophils.
Grade – 1

http://sdb.bio.purdue.edu/fly/vdevlhom/pdeath.htm
This site contains a great definition of apoptosis and introduces the term PCD – programmed cell death. It also contains a list of genes responsible for apoptosis in Drosophila and their homologues in mammals.
Grade – 4

http://www.geocities.com/CollegePark/Lab/1580/apoptosis.html
This site contains a very good introduction to apoptosis. It gives an example of where apoptosis did not occur in polydactyly – making it interesting to students. Later down the page it includes a small diagram of a cell-signaling pathway of apoptosis.

http://www.geocities.com/j_robens/apoptosis.html
This site gives information with a developmental biology perspective and gives a detailed explanation of apoptosis. Some of the points of interest on this website include thorough information regarding the role of the specific genes that are involved in apoptosis, the cell cycle, the difference between necrosis and apoptosis and many others.This site has clear diagrams and gives examples of good model systems.Rating-4.

http://www.naturesj.com/cdd/
This web site is the home page for the Cell Death and Differentiation Journal.It is a highly technical site focused on searching the journal for articles on specific topics relating to programmed cell death and apoptosis.Rating-4.

http://www.celldeath.de/mainfram.htm
Contains glossary, protocols, list of labs working in the field of apoptosis, a forum, and good links to other apoptosis websites including the link below.

http://www.medicine.uiowa.edu/pathology/path%5Ffolder/faculty/knudson/knudson.html
This link is to the homepage of a University of Iowa M.D., Ph.D.’s page and it includes links to his lectures on apoptosis which are very easy to follow and have good graphics including sample data from his research.This link would be helpful as a general resource for those interested in learning more about apoptosis.It’s not too technical, but some understanding of biology would be useful. Rating-4.