Yeast Knockouts - mTn Approach

Michael Snyder et al. (Yale)

Random insertional mutagenesis into yeast gDNA library.

Key mTn features:

What's Available?

Different Levels of Analysis

1) Macroarrays

Oxidative Phosphorylation
Cell Wall Synthesis
ade2 and red pigment formation
lysis and release alkaline phosphatase

2) Microarrays

3) Proteomics

4) "Phenomics"

5) Clustering of Phenomics

Significant Conclusions for GCAT:



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